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Prenatal, Perinatal, and Other Risk Factors of Attention-Deficit Hyperactivity Disorder in Soerojo Hospital Sutanto, Doddy BL; Sevriana, Ery Surya; Pangestuti, Rayi Citra Ayu; Hanifa, Yumna Nur Millati; Bangun, Susi Rutmalem
Journal of Maternal and Child Health Vol. 8 No. 3 (2023)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2023.08.03.08

Abstract

Background: Long-term negative effects on academic ability and social activities can persist into adulthood in children with neurodevelopmental disorders characterized by inattention, hype­r­activity, and impulsivity (Attention Deficit Hyperactivity Disorder/ ADHD). Genetic, neurotrans­mitter, neurological, environmental, psychosocial, brain trauma, and addictive factors are some of the predisposing factors for ADHD. But theoretically, maternal risk factors  often contribute to neuropsychiatric disorders, because of their potential influence on child brain development. This study aimed to assess the proportion of maternal risk factors consisting of prenatal, perinatal, and other factors of ADHD in Soerojo Hospital. Subjects and Method: A descriptive-analytic study with a retrospective approach was conducted on April-June 2022 at Soerojo Hospital. A total of 90 subjects pediatric patients diagnosed with ADHD selected by purposive sampling. The data were collected using questionnaires. The data were described in frequency (n) and percent (%). Results: The proportion of prenatal risk factors are mother’s age at pregnancy (19%), maternal disease history (8%), hormonal contraception pre-pregnancy (24%), maternal psychopathology (34%), maternal excess weight (49%); the proportion of perinatal risk factors are premature birth (12%), operative abdominal and vaginal delivery (49%), low birth weight (13%), neonatal emer­gencies (34%); while other factors are hereditary factors (13%), exposure to cigarettes (47%), and marital conditions (23%). Conclusion: The most common maternal risk factors were maternal excess weight, operative abdominal and vaginal delivery, exposure to cigarettes, maternal psychopathology, and neonatal emergencies. Keywords: ADHD, maternal risk factor, prenatal, perinatal. Correspondence: Doddy Sutanto, Department of Obstetric and Gynecology, Soerojo Hospital, Magelang, Indonesia, Jl. Ahmad Yani No. 169, Magelang 56115, Central Java. Email: doddysutanto.soerojo­hospital@­gmail.­com.
PENGETAHUAN DAN IMPLEMENTASI CAREGIVER DALAM PENGASUHAN ANAK ADHD: STUDI KUALITATIF Indah, Ana Puspita; Arrozaqi, Muhammad Rofi; Nirmalajati, Budhi; Isidora, Ismiyati; Triatmojo, Wahyu; Sevriana, Ery Surya; Pangestuti, Rayi Citra Ayu
Jurnal Ilmu Kesehatan Masyarakat Vol 19 No 4 (2023)
Publisher : Fakultas Kesehatan Masyarakat, Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/ikesma.v19i4.43799

Abstract

Gangguan perkembangan saraf yang ditandai dengan kurangnya perhatian, hiperaktif, dan impulsif pada anak, yang disebut Attention Deficit Hyperactivity Disorder (ADHD), menyebabkan anak ADHD menghadapi kesulitan dalam segala aspek kehidupan. Namun, hal ini dianggap sebagai beban bagi anggota keluarga atau orang-orang di sekitarnya. Meskipun demikian, peran keluarga atau caregiver sangat berpengaruh dalam memperbaiki kondisi anak ADHD. Penelitian ini bertujuan untuk menggali pengetahuan caregiver dalam merawat anak ADHD. Penelitian kualitatif dengan wawancara mendalam dilakukan di RSJ Prof. Dr. Soerojo Magelang pada bulan Juni hingga November 2022. Partisipan penelitian dipilih secara purposive sampling dan diperoleh 8 informan yang merupakan caregiver anak ADHD. Pada penelitian ini didapatkan empat tema utama mengenai pengetahuan caregiver dalam mengasuh anak ADHD, meliputi: sumber pengetahuan, definisi dan gejala ADHD, peran caregiver dalam merawat anak ADHD, dan penanganan ADHD. Semua informan tidak memiliki pengetahuan pasti tentang definisi ADHD tetapi mampu mengidentifikasi beberapa gejala dan penyebab ADHD. Informan juga memiliki pengetahuan tentang perannya dan menerapkannya dalam pengasuhan anak ADHD, meskipun mereka seringkali menghadapi beberapa kendala.
Effect of LAI Antipsychotics on Relapse Frequency and Adverse Drug Events of Schizophrenia Patients Sabar Parluhutan Siregar; Giyanto; Surya Sevriana, Ery; Pangestuti, Rayi Citra Ayu; Dewi, Wahyu Ratna
Jurnal Psikiatri Surabaya Vol. 14 No. 1 (2025): May
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v14i1.62938

Abstract

Introduction: Non-adherence to oral antipsychotic medication is common in schizophrenia patients, and it is very likely to lead to recurrence. Whereas the frequency of recurrence in schizophrenia is associated with poorer long-term outcomes and disease progression. The use of long-acting injectable (LAI) antipsychotics has become a favorable approach in the management of schizophrenia, especially to reduce relapse rates and minimize treatment-related side effects. The aim of this study was to evaluate the effect of using LAI antipsychotics, specifically fluphenazine decanoate, on the relapse rate of schizophrenia patients as well as to assess the potential associated side effects. Methods: This study was a quantitative analytical study design with a retrospective cohort approach involving 1102 schizophrenia patients in RSJ Prof. Dr. Soerojo Magelang who received LAI therapy (fluphenazine decanoate) in various administration frequencies and time intervals. Data on relapse frequency and adverse drug events were obtained from medical records and adverse drug events yellow forms. The bivariate test used was a Wilcoxon signed rank test. Results: The results showed that 77.86% of respondents received LAI with an administration interval ≥ 180 days, and 92% received LAI with low administration frequency (1–5 times). There was a significant decrease between the frequency of relapse in schizophrenia patients and the incidence of drug side effects before and after the administration of antipsychotic LAI. Conclusions: In this study, it was found that the use of antipsychotic LAI (fluphenazine decanoate) can significantly reduce the frequency of relapse and the incidence of adverse drug events in schizophrenia patients.
The Effect of Adverse Drug Reactions (ADRs) of Anti-psychotics on the Quality of Life of Outpatients with Schizophrenia at Soerojo Hospital, Magelang, Indonesia Hutama, Tifan Adji; Karuniawati, Hidayah; Pangestuti, Rayi Citra Ayu
Borobudur Pharmacy Review Vol. 6 No. 1 (2026): January- June
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/evxwjt61

Abstract

Mental disorders are serious conditions of the brain that manifest as abnormalities that affect a person's behavior and character. Schizophrenia is one type of mental disorder that is widely experienced by the community. The primary therapy for schizophrenia is anti-psychotics with routine and long-term medication, which leads to Adverse Drug Reactions (ADRs). ADRs that appear have the potential to affect the quality of life of schizophrenia patients. The purpose of this study was to determine the effect of ADRs on the quality of life of schizophrenia patients at Soerojo Hospital Magelang. The study used a cross-sectional design. The population in this study was patients diagnosed with schizophrenia with consecutive sampling. The instruments used were the Naranjo and WHOQOL-BREF questionnaires to assess the quality of life of schizophrenia patients. Data analysis was conducted univariately using frequency distributions and bivariately using the nonparametric Mann-Whitney test. During the study, 109 patients met the inclusion and exclusion criteria. The majority of patients were male (59.63%), aged 41-60 years (55.96%), had been on treatment for 4-10 years (75.23%), had a high school education (39.45%), were taking a combination of clozapine and risperidone (29.36%), ADRs (71.55%), and had a moderate quality of life (55.05%). The most common ADRs experienced by patients using first-generation anti-psychotics were tremor, nausea, dizziness, and excessive salivation, each occurring at 9.09%. Meanwhile, the most common ADR for second-generation anti-psychotics was drowsiness (34.03%). ADRs were not significantly related to the quality of life of schizophrenia patients (p = 0.941