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All Journal The Indonesian Biomedical Journal JOURNAL OF COMMUNITY MEDICINE AND PUBLIC HEALTH RESEARCH
Hasna, Iffa Halimah
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Biochemistry, Genetics & Molecular Biology Health Professions Medicine & Pharmacology Public Health

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NATIONAL HEALTH INSURANCE BASED TELEMEDICINE APPLICATION FOR HYPERTENSION MANAGEMENT IN PRIMARY LEVEL OF HEALTH FACILITIES Saputra, Pandit Bagus Tri; Izzati, Nabila; Rosita, Primadita Esther; Trilistyoati, Desy; Isyroqiyyah, Nur Moya; Hasna, Iffa Halimah; Putri, Niamita Eka Puspita; italoka, Ervina Dyah; Putra, Muhammad Rifqi Arya; Rahman, Andi Lestari; Djuari, Lilik
Journal of Community Medicine and Public Health Research Vol. 2 No. 1 (2021): Journal of Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (465.852 KB) | DOI: 10.20473/jcmphr.v2i1.25304

Abstract

Hypertension nowadays still becomes one of the severe problems in Indonesia, with a prevalence of 34% in 2018. The complication of hypertension causes the most deaths and disabilities in Indonesia and cost 75% of The Social Security Organizing Agency (BPJS) budget or IDR 15 trillion in 2019. This problem was probably caused by patients' lack of knowledge and limited personnel at the primary health centre (PHC). Telemedicine is a health care provider without any direct contact, which has various methods. Today, telemedicine in Indonesia is growing rapidly along with technology and legal regulation in its implementation, increasing users by 700% in the first year of 2020. Despite the rise of those numbers, telemedicine in PHC is still limited. Recently, the Ministry of Health and various organizations have issued telemedicine regulations at primary level health facilities in collaboration with The Social Security Organizing Agency. This review aims to discuss the current implementation and the potential future of telemedicine-based hypertension management in collaboration with the Social Security Organizing Agency in PHC.
Lactiplantibacillus plantarum IS-10506 Supplementation Improves Clinical Outcome and Immunology Markers in Psoriasis Vulgaris Patients: A Randomized Controlled Trial Umborowati, Menul Ayu; Hasna, Iffa Halimah; Endaryanto, Anang; Surono, Ingrid Suryanti; Prakoeswa, Cita Rosita Sigit
The Indonesian Biomedical Journal Vol 16, No 4 (2024)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v16i4.3155

Abstract

BACKGROUND: Probiotics may modify the gut microbiome and have been proven to improve psoriasis vulgaris. Lactiplantibacillus plantarum IS-10506 is a probiotic strain of Indonesian origin. It offers a safe and effective probiotic for psoriasis patients in Indonesia. This study was conducted to evaluate the effect of L. plantarum IS-10506 on clinical and immunology markers in psoriasis vulgaris.METHODS: This randomized, placebo-controlled, and double-blind trial compared L. plantarum IS-10506 (2×1010 CFU/day) and placebo in 49 patients mild-moderate psoriasis vulgaris, which were divided into intervention (n=24) and control groups (n=25). The interventions were given twice daily for 12 weeks. Both groups received topical corticosteroid and emollient as standard treatment. Psoriasis area and severity index (PASI), dermatology life quality index (DLQI), interleukin (IL)-10, IL-17, and forkhead box protein (Foxp3) were then assessed.RESULTS: Mean PASI score for the the subjects in probiotic group was significantly reduced compared to placebo at week-6 (p=0.024), and was sustained until week-12 (p=0.049). At week-12, DLQI scores in the probiotic group were lower than placebo (7.57±5.77 vs. 7.79±5.48). IL-17 level was significantly decreased (p=0.013), while the IL-10 and Foxp3 were significantly increased (p≤0.001 and p=0.048, respectively) in probiotic group. Six months after the completion of study, subjects in probiotic group had a lower probability of flares (52.2%) compared to placebo (79.2%). Two subjects receiving probiotics and one receiving placebo noticed changes in defecation frequency, while another subject in the placebo group complained of mild nausea.CONCLUSION: L. plantarum IS-10506 might effectively improve clinical outcomes and immune biomarkers in psoriasis vulgaris patients, potentially acting as an adjuvant therapy.KEYWORDS: psoriasis, probiotic, clinical severity, immune marker, human and health
Co-Authors Anang Endaryanto Cita Rosita Sigit Prakoeswa INGRID SURYANTI SURONO Isyroqiyyah, Nur Moya italoka, Ervina Dyah Izzati, Nabila Lilik Djuari Menul Ayu Umborowati, Menul Ayu Putra, Muhammad Rifqi Arya Putri, Niamita Eka Puspita Rahman, Andi Lestari Rosita, Primadita Esther Saputra, Pandit Bagus Tri Trilistyoati, Desy