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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin The Indonesian Biomedical Journal Indonesian Journal of Case Reports
Menul Ayu Umborowati, Menul Ayu
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Eosinophil and Eosinophil Cationic Protein Level Raising in Dermatitis Due to Food Patients Umborowati, Menul Ayu; Sawitri, Sawitri; Hoetomo, Marsoedi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 27, No 2 (2015): BIKKK AGUSTUS 2015
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (115.225 KB) | DOI: 10.20473/bikkk.V27.2.2015.90-96

Abstract

Background: Food allergy prevalence worldwide has been increase. Skin is secondary most often target organ in food allergy reaction. Food allergy affects 35% atopic dermatitis (AD) patients. Diagnosis of food allergy  is still challenge because signs are not specific. Previous researches showed eosinophil and eosinophil cationic protein (ECP) role in food allergy reaction on gastrointestinal tract, but none on dermatitis due to food. Purpose: To evaluate eosinophil and serum ECP in dermatitis due to food. Method: This is a descriptive observational cross sectional study, with dermatitis due to food patients in Dermatovenereology Outpatient Clinic Dr. Soetomo General Hospital Surabaya as subjects. Subjects has been collected trough consecutive sampling during 3 months, then data were analysized descriptively Results: Serum ECP level of dermatitis due to food patients were above normal range in all subjects, with mean level 108.5 µg/L, lowest level 33.011 µg/L and higher level 284.849 µg/L. Mean eosinophil of dermatitis due to food patients just arise above normal limit (0.413µg/L). AD patients were 48.4% among all subjects. Mean serum ECP level of AD patients was higher (121.703 µg/L) than non-AD (96.123 µg/L). Conclusions: Eosinophil and ECP seems have role in dermatitis due to food pathogenesis. Serum ECP examination can be benefits to monitor dermatitis due to food severity.Key words: dermatitis due to food, eosinophil, serum eosinophil cationic protein.
StudiRetrospektif:Diagnosis dan Terapi Pasien Melasma Umborowati, Menul Ayu; Rahmadewi, Rahmadewi
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol 26, No 1 (2014): BIKKK APRIL 2014
Publisher : Faculty Of Medicine Airlangga University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (388.071 KB) | DOI: 10.20473/bikkk.V26.1.2014.1-8

Abstract

Latar belakang:Melasmaadalah penyakit yang banyak dijumpai terutama dinegara beriklim tropis seperti Indonesia. Masalah yang dihadapi adalah responsterhadap terapiyang beragam, sehingga diagnosis dan terapi yang tepat untuk penyakit ini masih perlu terus dikembangkan.Tujuan: Mengevaluasi penegakan diagnosis dan pemberian terapi melasma guna meningkatkan pelayanan terhadap pasien di masa yang akan datang. Metode:Penelitian retrospektif pasienmelasma di Divisi Kosmetik Medik Unit Rawat Jalan (URJ) Kulit dan Kelamin RSUD Dr.Soetomo Surabaya selama periode 1 Januari 2009 sampai dengan 30Desember 2011. Data diperoleh dari rekam medis.Hasil:Pasienmelasma sebanyak 14,1% dari seluruh pasienbaru Divisi Kosmetik Medik, pasienperempuan sebanyak 99,2% dengan faktor pencetus utama adalah sinar matahari. Diagnosis ditegakkan dari pemeriksaan fisik dan lampu Wood, terapi topikal yang banyak diberikan adalah tabir surya, formula Kligman, dan Alpha Hydroxy Acid(AHA).Simpulan:Metode penegakan diagnosis dan pilihan agen pemutih sebagai terapi melasma di Divisi Kosmetik Medik URJ Kulit dan Kelamin RSUD Dr.Soetomo Surabaya masih perlu dievaluasi sesuai dengan bukti dan temuanterbaru.Kata kunci:melasma, studi retrospektif, diagnosis, terapi.
The Confusion between Pustular Psoriasis and Acute Generalized Exanthematous Pustulosis as a Cause of Exfoliative Dermatitis: A Case Report Sari, Desiana Widityaning; Damayanti, Damayanti; Anggraeni, Sylvia; Umborowati, Menul Ayu; Cita Rosita Sigit Prakoeswa; Ervianti, Evy
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.224-231

Abstract

Background: Pustular psoriasis and Acute Generalized Exanthematous Pustulosis (AGEP) are grouped under pustular diseases, in which their clinical manifestations are similar. Those diseases can lead to exfoliative dermatitis. Purpose:To evaluate a specific histopathological examination in differentiating Pustular Psoriasis and AGEP. Case: A 55-year-old woman presented with sudden redness and diffused scaly skin with multiple pustules and also fever. She had taken Cefadroxil 2 days before the scales and pustules appeared. Leukocytosis and histopathological examination results from biopsy supported the diagnosis of AGEP. The patient was then hospitalized and received steroid therapy. Within the first week of tapering off, the scales disappeared but the pustules increased. After such clinical findings, the histopathological examination results were revisited and reassessed. Thus, we considered changing the diagnosis to Pustular Psoriasis, and the therapy was switched to Methotrexate. The patient had a better outcome, and the pustules slowly disappeared entirely. Discussion: It is often difficult to differentiate between the pustules in pustular psoriasis and AGEP unless by thorough history-taking and physical examinations. AGEP is characterized by a widespread of pustules with an acute febrile onset; while pustular psoriasis is an acute variant of psoriasis where pustules are spread over erythematous skin and accompanied by high fever and leukocytosis. Conclusion: Histopathological examination is the gold standard for the establishment of pustular psoriasis diagnosis. The histopathological characteristics of pustular psoriasis and AGEP are difficult to differentiate. Therefore, we need detailed history-taking and physical examination to establish the diagnosis.
Efficacy and Side Effects of Fractional Carbon Dioxide Laser for Acne Scars, Keloids, and Striae Albae in the Dermatovenereology Clinic of Tertiary Hospital: A Retrospective Study Pramitha, Riezky Januar; Zulkarnain, Iskandar; Ervianti, Evy; Rahmadewi, Rahmadewi; Hidayati, Afif Nurul; Budiono, Budiono; Indramaya, Diah Mira; Setyaningrum, Trisniartami; Citrashanty, Irmadita; Sari, Maylita; Umborowati, Menul Ayu; Kusumaputra, Bagus Haryo; Listiawan, Muhammad Yulianto
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 1 (2021): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.1.2021.19-27

Abstract

Background: Fractional Carbon Dioxide (CO2) LASER has better efficacy compared to conventional LASER in treating scar tissue such as acne scars, keloids, and striae albae. However, a population with darker skin has a higher risk of side effects, especially in post-inflammatory hyperpigmentation. Purpose: To evaluate the efficacy and side effects of fractional CO2 LASER in new patients with acne scars, keloids, and striae albae in the Dermatovenereology outpatient clinic. Methods: Retrospective analysis was done on 42 medical records of patients who met the inclusion criterion, which was those who have undergone fractional CO2 LASER treatments. The efficacy and side effects of the therapy were identified and analyzed using the Statistical Package for Social Sciences (SPSS) version 17 program. Result: A total of 42.9% of patients underwent fractional CO2 LASER treatments for acne scars, while 31% and 26.1% of patients received treatments for keloids and striae albae, respectively. There was a statistically significant decrease in the degree of acne scar (2.72 ± 0.83), keloid height (2.2 ± 0.405), and striae width (0.39 ± 0.02). The statistically significant side effects were hyperpigmentation (59.5%), crustae (26.2%), erythema ≥ for 4 days (19%), and new acne (19%). Conclusion: Fractional CO2 LASER was effective for treating scar tissue (acne scars, keloids, and striae albae) with a higher incidence of side effects in population with darker skin and post-inflammatory hyperpigmentation.
Contact Dermatitis Knowledge Level in Batik Workers of Desa Batik, Tanjung Bumi, Bangkalan, Madura Prakoeswa, Cita Rosita Sigit; Rahmadewi, Rahmadewi; Setyaningrum, Trisniartami; Damayanti, Damayanti; Anggraeni, Sylvia; Mappamasing, Hasnikmah; Umborowati, Menul Ayu
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 2 (2021): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.2.2021.93-95

Abstract

Background: Batik has been declared as a humanitarian heritage for oral and non-cultural culture. The increasing demand for batik may have a negative impact as the industry utilizes chemical agents. Hazardous chemical exposure to the skin in the batik industry may result in a high risk of occupational contact dermatitis. This study was conducted to find out the social determinants of health. Purpose: This study aims to assess the level of knowledge of the batik workers before and after health education about occupational contact dermatitis. Methods: This was an observational interview study, and the data were collected using questionnaires. This study involved 30 batik workers.  We assessed the level of knowledge before and after the health education about occupational contact dermatitis. Result: There were 4 (13.3%) male participants and 26 (86.7%) female participants. The mean score of the pre-test was 66.98±10.10, and the post-test was 77.77±13.53 (p<0.05). Conclusion: The result showed a significant difference between batik workers' knowledge before and after health education about contact dermatitis.
The Profile of Psoriasis Vulgaris Patients: A Descriptive Study Hidayati, Afif Nurul; Hendaria, Made Putri; Listiawan, M. Yulianto; Utomo, Budi; Damayanti, Damayanti; Prakoeswa, Cita Rosita Sigit; Anggraeni, Sylvia; Umborowati, Menul Ayu; Citrashanty, Irmadita; Ervianti, Evy
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.173-181

Abstract

Background: Psoriasis is a skin disease that occurs due to proliferation and differentiation disturbances of the epidermis. This chronic condition often reduces the human quality of life. There have been studies investigating psoriatic patient profiles and treatments, but few are conducted in Surabaya. Hence, those studies cannot fully represent the population demographic in Surabaya. Purpose: To investigate the prevalence of psoriasis vulgaris and the sociodemographic profile of the patients in Dr Soetomo General Academic Hospital. Methods: This was a Retrospective study psoriasis vulgaris patients in January 2016–December 2018. The data were collected by retrieving Electronic Medical Records (EMR) as secondary data. Result: The psoriasis vulgaris prevalence of outpatients was 0.46% and 4.59% in inpatients. Most study subjects were adults aged 18 and above (98.1%), most of the patients were obese (46.3%), the most common provoking factor was focal tooth infection (33.8%) and stress (28.8%), and none reported family history of psoriasis. Conclusion: Some results are similar to other studies conducted in Surabaya, which were the obesity and Type 2 Diabetes Mellitus (DM) being strong a factor to psoriasis development. However, the result on psoriasis family history was not in line with other studies.
Prevention of Contact Dermatitis Due to Hand Hygiene in The Era of COVID-19 Damayanti, Damayanti; Anggraeni, Sylvia; Prakoeswa, Cita Rosita Sigit; Umborowati, Menul Ayu
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 33 No. 3 (2021): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V33.3.2021.162-167

Abstract

Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus is known to cause COVID-19 (Coronavirus Disease 2019), and it is rapidly spreading throughout the world that it is declared as a global pandemic. Hand hygiene is widely promoted as it is recommended to reduce the risk of COVID-19 transmission. Contact dermatitis is one of the risks of hand hygiene campaign during the COVID-19. Purpose: This study aimed to assess the parents' level of knowledge before and after health education about contact dermatitis due to hand hygiene. Methods: This was a cross-sectional study, and the data was collected via questionnaires. This study involved 53 respondents. Result: There was a significant increase in respondents' knowledge level after being educated (Wilcoxon test, p=0.000), as evidenced in the mean score of pre-test and post-test evaluation. Conclusion: To lower the incidence, education on contact dermatitis prevention due to hand hygiene during the COVID-19 pandemic is required.
Henoch-Schonlein Purpura in Adult with Gastrointestinal and Renal Involvement Devi, Aprilin Krista; Umborowati, Menul Ayu; Anggraeni, Sylvia; Damayanti, Damayanti; Cita Rosita Sigit Prakoeswa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 1 (2023): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.1.2023.74-80

Abstract

Background: The pathogenesis of Henoch-Schonlein Purpura (HSP), a multisystem organ-involved small vessel vasculitis, is unknown. HSP is more common in youngsters than in adults. HSP is associated with a history of malignancies, medications, vaccinations, and upper respiratory tract infections. Painful purpura, arthritis, stomach discomfort, and renal involvement are symptoms that may be seen in HSP patients. Adult patients had a much higher rate of renal involvement than children. Purpose: To report a case of HSP in an adult with gastrointestinal and renal involvement. Case: A 45-year-old man complained of an arm, leg, and waist rash for two weeks before admission to the hospital. He also has stomach pains, nausea, and vomiting to deal with. His symptoms have just appeared now for the first time. During a renal function test, blood urea nitrogen (BUN) and creatine serum levels rose. On a urinalysis, proteinuria and microscopic hematuria were found. Leucocytoclastic vasculitis was discovered during the histopathology investigation. HSP diagnosis was based on the ACR and ICC criteria. The patient was given 3x2 tablets of 0.5 mg dexamethasone, 3x2 tablets of cetirizine, 2x10 mg lisinopril, 2x50 mg ranitidine injection, and 2 grams ceftriaxone. Discussion: The clinical symptoms of HSP are used to make the diagnosis. In the vast majority of instances, the treatment is only supportive therapy. Corticosteroid usually are usually used for HSP with multisystem organ involvement to reduce pain severity and faster resolution of renal manifestation. Conclusion: Follow up on renal function is needed to monitor the worsening of renal disease.
Occupational Contact Dermatitis Risk Factors on Healthcare Workers Isolation Ward During the COVID-19 Pandemic Yuindartanto, Andre; Sawitri; Astindari; Damayanti; Anggraen, Sylvia; Umborowati, Menul Ayu; Zulkarnain, Iskandar; Listiawan, M. Yulianto; Hidayati, Afif Nurul; Cita Rosita Sigit Prakoeswa
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 35 No. 1 (2023): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V35.1.2023.27-39

Abstract

Background: After a history of exposure to the suspected material and a thorough physical examination, the diagnosis of occupational contact dermatitis (OCD) is commonly suspected. During the initial consultation, essential information involving the above is frequently neglected. Purpose: To evaluate the clinical manifestations of OCD cases in health workers and analyze the factors that influence OCD cases in health workers at the isolation ward of Dr. Soetomo Surabaya Hospital during the COVID-19 pandemic. Methods: The sample selection was done through purposive sampling. Accessible population that met the inclusion criteria and did not have exclusion criteria were included as research samples. The target population was healthcare workers in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The accessible population was healthcare workers who performed hand hygiene activities and used Personal Protective Equipment (PPE) in the Special Isolation Ward of Dr. Soetomo Hospital Surabaya. The research subjects were healthcare workers who worked in the Special Isolation Ward. Result: The research results showed a strong and significant correlation between atopic history and the occurrence of contact dermatitis due to poor skin barrier function and decreased tolerance. The study also found that there was no significant correlation between atopic history and the severity level of OCD. There was a significant difference in transepidermal water loss (TEWL) values in the lesion and non-lesion areas, both on the palmar and dorsal aspects of the hand. Moisturizer is an important component in managing hand dermatitis as it can repair and maintain the skin's protective barrier. Conclusion:
Description of Hanifin-Rajka Criteria and Skin Hydration in Adult Patients with Mild-Moderate Atopic Dermatitis at Tertiary Hospital Umborowati, Menul Ayu; Jastika, Faradistiani Rakhmawati; Hendaria, Made Putri; Anggraeni, Sylvia; Damayanti; Sari, Maylita; Prakoeswa, Cita Rosita Sigit
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 1 (2024): APRIL
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.1.2024.20-25

Abstract

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disorder that typically manifests in childhood and has a diverse etiology. In the United States, the prevalence of AD among adults was 4.9%, while in Japan it was 2.1%. The majority of people with AD have dry skin. Hanifin-Rajka criteria were the first to be established and are frequently used as diagnostic standards in research. Purpose: The purpose of this study is to determine the Hanifin-Rajka criteria and skin hydration in adult patients with mild-moderate atopic dermatitis at Dr. Soetomo General Academic Hospital, Surabaya March-May 2022.  Methods: This cross-sectional descriptive study included adult patients with mild to moderate AD according to Hanifin-Rajka aged 18-64 years who visited the Dermatology and Venereology Outpatient Dr. Soetomo General Academic Hospital Surabaya between March and May 2022. Skin hydration was measured using a corneometer on the volar side of the left forearm in the skin area.  Result: Based on the major criteria, all participants had pruritus, typical morphology and distribution, and chronic or chronically recurrent dermatitis. As for the minor criteria, more varied results were obtained, one of which was xerosis, which was experienced by all participants. The skin hydration shows that the mean value for skin hydration was 39.8 ± 12.1. The lowest skin hydration was 21.4 and the highest was 87.4, both found in subjects with mild AD. Conclusion: ..
Co-Authors Afif Nurul Hidayati, Afif Nurul Anang Endaryanto Anggraen, Sylvia Anggraeni, Sylvia Astindari Bagus Haryo Kusumaputra, Bagus Haryo Budi Utomo Budiono Budiono Cita Rosita Sigit Prakoeswa Damayanti Damayanti Damayanti Devi, Aprilin Krista Diah Mira Indramaya Earlia, Nanda Evy Ervianti Hasna, Iffa Halimah INGRID SURYANTI SURONO Irmadita Citrashanty, Irmadita Jastika, Faradistiani Rakhmawati Liana, Mahda Rizki M. Yulianto Listiawan Made Putri Hendaria Mappamasing, Hasnikmah Marsoedi Hoetomo Maylita Sari, Maylita Mikyal Bulqiah, Mikyal Pradistha, Aldilla Pramitha, Riezky Januar Rahmadewi Rahmadewi Sari, Desiana Widityaning Sawitri Sawitri Sawitri Tasrif, Aqil Yuniawan Tengku Riza Zarzani N Trisniartami Setyaningrum Yuindartanto, Andre