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All Journal Universa Medicina Medical and Health Science Journal Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Indonesian Journal of Cancer Biomedika
Kusharsamita, Hillary
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

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Chronic limb ischemia manifestation in COVID-19 infection: awareness and treatment in primary care Laksono, Sidhi; Siregar, Reynaldo Halomoan; Kusharsamita, Hillary
Universa Medicina Vol. 40 No. 2 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.166-175

Abstract

Chronic limb ischemia (CLI) is a type of peripheral arterial disease (PAD) that is still underdiagnosed and undertreated despite the increasing incidence, thus becoming a global health burden. And CLI reflects the local manifestations of a lethal systemic disease — atherosclerosis. If left untreated, chronic limb ischemia can result in major limb loss. In this pandemic era, limb ischemia has become one of several clinical manifestations that occur in patients with COVID-19 infection. Systemic inflammation in COVID-19 infection, direct viral infection, hypercoagulable state, and hyperinflammatory response are responsible for damage to the arterial system, causing endothelial dysfunction. Diagnosing PAD has become a challenge especially in the early stage and in the asymptomatic phase. The untreated condition could lead to the development of CLI. The primary physicians in the primary health facilities hold an important role in the early diagnosis and management of patients with CLI symptoms or with risk factors of CLI, especially in patients who have experienced COVID-19 infection. Due to the limitation of diagnostic testing modalities at primary health facilities, the physician can assess the ankle-brachial index (ABI) to determine the presence of CLI. Management of the disease is different for every patient and is customized based on the other comorbidities. Risk factors should be controlled in order to achieve a better outcome. A good management strategy will improve the quality of life of the patient. This review will discuss the occurrence of CLI in COVID-19 infection.
Supraventricular Tachycardia Induced by Cisplatin in a Patient with Breast Cancer: A Case Report Laksono, Sidhi; Kusharsamita, Hillary
Indonesian Journal of Cancer Vol 18, No 2 (2024): June
Publisher : http://dharmais.co.id/

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33371/ijoc.v18i2.1066

Abstract

Introduction: Cisplatin is one of the most extensively used chemotherapeutic agents for treating many malignancies. Cisplatin chemotherapy, on the other hand, is linked to cardiotoxicity, which may vary from silent arrhythmias to heart failure to sudden cardiac death. In this article, we describe a case of supraventricular tachycardia induced by cisplatin in a breast cancer patient. Case Presentation: Our patient had no history of heart disease and had SVT during cisplatin administration. This condition resolved when the infusion was stopped and amiodarone was administered intravenously. The electrolyte levels were within the usual range. No abnormalities were detected on her echocardiography imaging. Primary cardiotoxicity from cisplatin was subsequently determined to be this patient's root cause of SVT. The patient also had an excellent response to the subsequent cycles of treatment. Conclusions: It is important to note that cisplatin therapy is associated with cardiac toxicity. Arrhythmias such as SVT have been associated with chemotherapy drugs. Hence the ECG has to be closely monitored during cisplatin administration. In addition, An ECG and echocardiogram should be done regularly to rule out the possibility of a secondary form of chemotherapy-induced arrhythmia. 
Navigating the Uncommon: Case Report of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Successfully Managed with Implantable Cardioverter Defibrillator (ICD) Purwowiyoto, Sidhi Laksono; Hermawan; Kusharsamita, Hillary
Jurnal Ilmu Kesehatan dan Kesehatan Vol 8 No 02 (2024): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v8i02.5666

Abstract

With a high risk of sudden cardiac mortality, arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare inherited cardiomyopathy characterized by right ventricular dysfunction and ventricular arrhythmias (VA). In this case study, a 35-year-old presented with palpitations and revealed epsilon waves on the right precordial electrocardiogram (ECG) leads which led to the suspicion of ARVC. A 24-hour Holter monitoring revealed frequent ventricular extrasystoles (>500 per 24 hours), a CMRI revealed RV dyskinesia and transmural LGE in the apical RV, and an electrophysiologic study detected spontaneous polymorphic ventricular tachycardia (VT) despite the presence of induction ventricle fibrillation (VF). These results validated the diagnosis of ARVC and indicated that an implantable cardioverter defibrillator was necessary treatment. The ability to identify potential ARVC’s ECG abnormalities, the timing to pursue further studies, and determining necessary treatment execution are critical. The evaluation of cardiac, electrophysiological, and clinical imaging parameters is essential for the risk stratification, diagnosis, and management of patients with ARVC.
Kasus Langka Pseudoaneurisma Arteri Radial Pasca Angiografi Koroner Laksono, Sidhi; Kusharsamita, Hillary
Majalah Kedokteran Indonesia Vol 74 No 6 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.6-2024-1531

Abstract

Introduction: Radial artery pseudoaneurysm is a rare but potentially severe complication that may occur after coronary angiography. Although uncommon, promptly identifying and addressing the issue is crucial to avoid further complications. Case Report: Here, we describe the case of a 65-year-old female patient who developed a radial artery pseudoaneurysm after undergoing coronary angiography to evaluate her chest discomfort. The diagnosis of a pseudoaneurysm was confirmed by Doppler ultrasonography, which identified a swirling flow pattern. Persistent pain symptoms and ineffective conservative treatment necessitated surgery.Case Discussion: This case highlights the importance of vigilance in identifying rare complications such as radial artery pseudoaneurysm following coronary angiography. Conclusion: Prompt diagnosis and appropriate management strategies, including surgical intervention, when necessary, are crucial for optimal patient outcomes.
COMPLICATIONS SURVEY OF PERCUTANEOUS CORONARY INTERVENTION: A CROSS-SECTIONAL STUDY Laksono, Sidhi; Kusharsamita, Hillary
Biomedika Vol 17, No 1 (2025): Biomedika August 2025
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v17i2.3327

Abstract

The purpose of this research is to examine the perspectives of interventional cardiologists, and the annual incidence of each PCI complications. This study is based on a cross-sectional analysis conducted using the Google Forms. The technique for determining the research subject used in this study was non-random sampling with purposive sampling technique. The anonymity and confidentiality of the information collected is highly prioritized. Annual PCI incidence rates are as follows: 100 (13%) 100–199 (13%), 200–299 (35%) 300 and above (38%). With a mean score of 5.56 on a scale from 0 to 10, participants are very concerned about the possibility of PCI complications. Coronary perforation is the most concerning complication of PCI (83%). Annually, coronary artery dissection occurred between once and five times (73%), coronary perforation occurred between once and five times (50%), and hemodynamic collapse was occurred at one to five times (60.9%). Further, 78.3% of participants never used covered stents, while 32% of participants used balloon tamponade at least one to five times each year. Participating interventional cardiologists in our research have concerns about possible PCI complications. Perforations, dissections, hemodynamic collapse, no-reflow, and entrapment equipment are complications that operators must be ready to identify and control.
Co-Authors HERMAWAN Laksono, Sidhi Purwowiyoto, Sidhi Laksono Siregar, Reynaldo Halomoan