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APLIKASI KLINIS EKOKARDIOGRAFI DUA DIMENSI SPECKLE TRACKING PADA PASIEN GAGAL JANTUNG Purwowiyoto, Sidhi Laksono
Jurnal Kedokteran YARSI Vol 25, No 1 (2017): JANUARI - APRIL 2017
Publisher : Lembaga Penelitian Universitas YARSI

Gagal jantung masih menjadi penyebab utama meningkatnya angka morbiditas dan mortalitas di seluruh dunia. Penilaian fungsi kardiak yang akurat masih menjadi kendala dalam mempertimbangkan prognosis dan terapi pasien gagal jantung. Ekokardiografi merupakan modalitas pencitraan yang dapat membantu menilai kemampuan kardiak pada pasien gagal jantung. Terdapat beberapa aplikasi yang dapat dipergunakan dalam menilai fungsi kardiak selain dari fraksi ejeksi kardiak, salah satunya penilaian speckle tracking. Dimana pemeriksaan ini merupakan non-Doppler, tidak tergantung sudut pengambilan dan kuantifikasi secara objektif dari deformasi miokardium dan proses dinamik ventrikel kiri sistolik serta diastolik. Artikel ini akan membahas mengenai aplikasi klinis speckle tracking pada pasien gagal jantung. Kata kunci: speckle tracking, strain, gagal jantung

Stem Cell Therapy for Ischemic Heart Disease: Clinical Use PURWOWIYOTO, Sidhi Laksono
Sanus Medical Journal Vol. 1 No. 1 (2020)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.5402

Ischemic heart disease is still becoming a cause of morbidity and mortality in the world. Regenerative cellular or stem cell therapy is a new and emerging as an alternative option for this disease. There are several stem cell types that used in ischemic heart disease, most used stem cell for this treatment are bone marrow-derived stem cell and mesenchymal stem cell. The mechanism of action for stem cell therapy is depends on transdifferentiation and paracrine effect. It effects the release of cytokines, chemokines and growth factors that inhibits apoptosis and fibrosis, enhance contractility and activate regenerative mechanism. Factors associated with the efficacy of stem cell therapy are delivery route to target myocardium, number of stem cell infusion, injection timing, physical condition of patient and stem cell microenvironment.

Chronic Limb Ischemia: Awareness and Treatment in Primary Care Purwowiyoto, Sidhi Laksono; Halomoan, Reynaldo
Sanus Medical Journal Vol. 5 No. 1 (2023)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i1.6347

Chronic limb ischemia (CLI) is a type of peripheral arterial disease (PAD) that is still underdiagnosed and undertreated despite the increasing incidence, thus becoming a global health burden. The prevalence of PAD is quite high, approximately around 200 million globally in the adult population and increased drastically in older age population. It might be difficult to diagnose at an early stage because around 20-50% patients may be asymptomatic. More than 70% of primary physicians also did not notice that the diagnosis was already established during screening of the PAD patients. All these problems could increase the incidence of PAD in the following year. The untreated conditions will develop into a more severe form of PAD known as chronic limb-threatening ischemia (or critical limb ischemia), and patients are at a higher risk of having limb loss, and also increased morbidity and mortality. The primary physicians in the primary health facilities hold an important role in the early diagnosis and management of patients with CLI symptoms or with risk factors of CLI. Due to the limitation of diagnostic testing modality at primary health facilities, the physician can assess the ankle-brachial index (ABI) to determine the presence of CLI. Management of the disease is different for every patient and is customized based on the other comorbidities. Risk factors should be controlled in order to achieve a better outcome. A good management strategy will improve the condition. This review aims to describe how to give an early diagnosis and management for CLI patients in primary health care.

Telekardiologi dan Aplikasinya: Pendekatan Rumah Sakit selama Pandemi Purwowiyoto, Sidhi Laksono; Achadi, Anhari; Wibowo, Adik
Sanus Medical Journal Vol. 2 No. 1 (2021)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v1i1.6519

Covid19 has changed how we serve patients in all areas of health, and cardiology is no exception. Telemedicine is an option that hospitals can do during this pandemic. Telecardiology is part of telemedicine. By transmitting clinical data and electrocardiograms, telecardiology allows access to cardiology consultation services (telecardiology) without the need to travel to the practice area for both patients and cardiologists. These services can be in the form of teleconsultation, teleelectrocardiography, telerehabilitation, or teleechocardiography. Telecardiology can be applied in prehospital (teleconsultation, teleelectrocardiography,) if there is a referral for a heart attack patient or consult for chronic heart disease through online mediaÍ¾ at the hospital in the form of discussions with peripheral hospitals and referral hospitals (teleechocardiography with other small hospitals)Í¾ and posthospital treatment can be performed for cardiac telerehabilitation in patients with heart failure or teleconsultation of posttreatment patients.

PULMONARY EMBOLISM WITH ANTIPHOSPHOLIPID SYNDROME: A CASE REPORT Purwowiyoto, Sidhi Laksono; M, Ferel; R, Yeria; Halomoan, Reynaldo; Kurniawan
Sanus Medical Journal Vol. 2 No. 2 (2021)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v2i2.7256

Antiphospolypid síndrome (APS) is a systemic autoimmune condition that is related to vascular thrombosis. Patients with APS are at risk for developing pulmonary embolism (PE) events. In this case, we present a 68 years old female with complaints of sudden onset of persistent shortness of breath for two days. No past medical history was identified. Physical and diagnostic examination revealed the presence of PE and antiphospolipid antibodies. Diagnosis of PE and APS were made. Patients then received initial anticoagulant using enoxaparin subcutaneously. Initial anticoagulants in patients with APS and PE should be administered. However, it is important to choose the right anticoagulant. DOAC is contraindicated due to the increased risk of thromboembolic events.

Strategi Pemasaran pada Sistem Layanan Kesehatan Purwowiyoto, Sidhi Laksono; Ananda Vilda, Cattleya; Indri Priyobodo, Dionisius; Raisa Cicilia, Ivana
Sanus Medical Journal Vol. 4 No. 2 (2022)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v4i2.8062

Health marketing is interdisciplinary because it uses certain concepts, methods, and techniques for classical and social marketing. The specialty of health marketing is that there are services and markets but no money equivalent. Healthcare marketing differs mainly by the nature of the demand for health services. The beneficiary may not be the target of a marketing campaign, and the physician decides what, where, when, and how much to provide for a particular service. To understand the impact of marketing strategies on healthcare quality, it is essential to understand today's medical consumers who prefer to seek medical information online. They also have many health services, healthcare providers, and reviews from patients who contact providers.

Korelasi Lama Menjalani Hemodialisis Dengan Kualitas Hidup Pada Penderita Nefropati Diabetik Di RS Dinda Tangerang Dalam Periode 3 Tahun Nugraha, Dhiki; Hasan, Fahad; Gunawandjati, Dedy; Purwowiyoto, Sidhi Laksono; Stujana, Endin Nokik; Hidayat, Ahmad
Sanus Medical Journal Vol. 5 No. 1 (2023)
Publisher : Universitas Muhammadiyah Prof. Dr. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/sanus.v5i1.9601

Pendahuluan: Salah satu komplikasi mikrovaskular dari diabetes yaitu nefropati diabetik. Penderita nefropati diabetik yang menjalani hemodialisis membutuhkan waktu yang lama dan membutuhkan kepatuhan dalam mengobati komorbid yang mendasarinya. Hal ini akan memberikan stresor baik fisiologis maupun psikologis penderita yang akan mempengaruhi kualitas hidup. Tujuan penelitian ini menentukan korelasi antara lamanya menjalani terapi hemodialisis pada penderita nefropatik diabetik dengan kualitas hidup di RS Dinda Tangerang. Metode: metode penelitian menggunakan analisis parametrik dengan metode pendekatan non parametrik. sampel penelitian ini menggunakan consecutive sampling yang melibatkan 40 penderita nefropati diabetik. data di analisis menggunakan korelasi spearman. Teknik pengumpulan data menggunakan kuesioner KDQOL SF 1.3. Hasil: berdasarkan hasil penelitian didapatkan 23 penderita 57.5% yang menjalani hemodialisis 1- 3 tahun dan 6 di antara nya penderita yang memiliki kualitas hidup kurang sebanyak 2 orang, dan yang memiliki kualitas hidup cukup sebanyak 2 orang serta sebanyak 15 orang lainya memiliki kualitas hidup baik. Simpulan: kesimpulan penelitian ini terdapat korelasi yang bermakna p=0,043 antara lama menjalani hemodialisis dengan kualitas hidup dengan nilai (r): 0.309 yang mana mengarah ke arah positif sehingga ketika penderita telah lama melakukan terapi hemodialisis maka semakin baik kualitas hidup dari penderita.

Navigating the Uncommon: Case Report of Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Successfully Managed with Implantable Cardioverter Defibrillator (ICD) Purwowiyoto, Sidhi Laksono; Hermawan; Kusharsamita, Hillary
Jurnal Ilmu Kesehatan dan Kesehatan Vol 8 No 02 (2024): AUGUST
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/mhsj.v8i02.5666

With a high risk of sudden cardiac mortality, arrhythmogenic right ventricular cardiomyopathy (ARVC) is a rare inherited cardiomyopathy characterized by right ventricular dysfunction and ventricular arrhythmias (VA). In this case study, a 35-year-old presented with palpitations and revealed epsilon waves on the right precordial electrocardiogram (ECG) leads which led to the suspicion of ARVC. A 24-hour Holter monitoring revealed frequent ventricular extrasystoles (>500 per 24 hours), a CMRI revealed RV dyskinesia and transmural LGE in the apical RV, and an electrophysiologic study detected spontaneous polymorphic ventricular tachycardia (VT) despite the presence of induction ventricle fibrillation (VF). These results validated the diagnosis of ARVC and indicated that an implantable cardioverter defibrillator was necessary treatment. The ability to identify potential ARVC’s ECG abnormalities, the timing to pursue further studies, and determining necessary treatment execution are critical. The evaluation of cardiac, electrophysiological, and clinical imaging parameters is essential for the risk stratification, diagnosis, and management of patients with ARVC.

Edukasi Kader Puskesmas dalam Deteksi Dini Penyakit Jantung Koroner Purwowiyoto, Sidhi Laksono; Stujanna, Endin Nokik; Nurusshofa, Zahra; Permatasari, Tiara; Hayati, Siti Lawuny
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.232

Penyakit Jantung Koroner (PJK) merupakan salah satu spektrum penyakit jantung yang paling umum di dunia, dengan tingkat morbiditas dan mortalitas yang tinggi. Pada tahun 2020, PJK diperkirakan menjadi penyebab utama kematian global, menyumbang 36% dari seluruh kematian, angka ini dua kali lipat dibandingkan kematian akibat kanker. Di Indonesia, PJK (yang termasuk dalam kategori penyakit sistem sirkulasi) tercatat sebagai penyebab utama kematian, dengan angka 26,4%, atau empat kali lebih tinggi dibandingkan kematian akibat kanker yang hanya sebesar 6%. Dengan demikian, sekitar satu dari empat kematian di Indonesia disebabkan oleh PJKKader puskesmas berfungsi sebagai perpanjangan puskesmas dalam menjangkau dan melayani masyarakat di area kerjanya. Berdasarkan permasalahan ini, kegiatan pengabdian masyarakat bertujuan memberikan edukasi kepada kader puskesmas tentang deteksi dini, pencegahan PJK, dan faktor risikonya. Dengan demikian, kader diharapkan dapat mengedukasi masyarakat dan mendorong mereka untuk melakukan deteksi dini serta pencegahan PJK guna mengurangi angka kematian akibat penyakit ini. Setelah pelaksanaan edukasi, terjadi peningkatan pengetahuan kader tentang PJK, yang terlihat dari kenaikan nilai pretest ke post-test sebesar 19,3%.

Edukasi Kader Puskesmas dalam Deteksi Dini Penyakit Jantung Koroner Purwowiyoto, Sidhi Laksono; Stujanna, Endin Nokik; Nurusshofa, Zahra; Permatasari, Tiara; Hayati, Siti Lawuny
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 1 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i01.232

Penyakit Jantung Koroner (PJK) merupakan salah satu spektrum penyakit jantung yang paling umum di dunia, dengan tingkat morbiditas dan mortalitas yang tinggi. Pada tahun 2020, PJK diperkirakan menjadi penyebab utama kematian global, menyumbang 36% dari seluruh kematian, angka ini dua kali lipat dibandingkan kematian akibat kanker. Di Indonesia, PJK (yang termasuk dalam kategori penyakit sistem sirkulasi) tercatat sebagai penyebab utama kematian, dengan angka 26,4%, atau empat kali lebih tinggi dibandingkan kematian akibat kanker yang hanya sebesar 6%. Dengan demikian, sekitar satu dari empat kematian di Indonesia disebabkan oleh PJKKader puskesmas berfungsi sebagai perpanjangan puskesmas dalam menjangkau dan melayani masyarakat di area kerjanya. Berdasarkan permasalahan ini, kegiatan pengabdian masyarakat bertujuan memberikan edukasi kepada kader puskesmas tentang deteksi dini, pencegahan PJK, dan faktor risikonya. Dengan demikian, kader diharapkan dapat mengedukasi masyarakat dan mendorong mereka untuk melakukan deteksi dini serta pencegahan PJK guna mengurangi angka kematian akibat penyakit ini. Setelah pelaksanaan edukasi, terjadi peningkatan pengetahuan kader tentang PJK, yang terlihat dari kenaikan nilai pretest ke post-test sebesar 19,3%.

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