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All Journal Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Yarsi Dental Journal
Rani Handayani
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Dentistry Engineering

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Model Shrinking Core Pada Isolasi Kitosan Dari Limbah Ebi Rani Handayani; Ahmad Fadli; Amun Amri
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 5 (2018): Edisi 2 Juli s/d Desember 2018
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains

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Abstract

Chitosan is derived from chitin compound used in the biomedical field. Chitosan can be synthesized from ebi waste using chemical methods through the deproteination, demineralization and the deacetylation processes. The aims of this study are to determine the effect of NaOH concentration on the degree of deacetylation chitosan synthesis and to determine the model that can describe the kinetics reaction via Shrinking Core Model (SCM) approach. The procedure of research was started by ebi waste size reduction. Ebi powder was reacted with NaOH 3.5% (deproteination), ratio 1:10 (w/v) for 2 hours stirring by 150 rpm. The deproteination product was reacted with HCl 1 N (demineralization), ratio 1:15 (w/v) for 1 hour stirring by 150 rpm. Then the product was reacted using NaOH 40%, 50%, and 60% (deacetylation), ratio 1:20 (w/v) at a temperature of 120oC with stirring by 150 rpm for 2 hours. Samples were taken every 10 minutes rise as much as 10 mL, washed until pH neutral and it dried. Deacetylation degree of chitosan was analyzed using acid-base titration method. The results showed that the higher the concentration, the higher the degree of deacetylation of the chitosan will be namely 72.63% to 79.32% at a temperature of 120oC. The best reaction kinetics model to describe the occur in the synthesize of chitosan was a model 2, that was a layer (chitosan) to control with the equation as:Model 2 is the best kinetic’s model with shrinking reacted core model on synthesize of citosan and ebi waste.Keywords: deacetylation, reaction kinetics, chitosan, waste ebi, shrinkingcore model.
Temuan Klinis Oral pada Pasien HIVAIDS di Poli Penyakit Mulut RSUD Kota Tangerang Mersil, Sarah; Miyuri Areta; Rani Handayani
YARSI Dental Journal Vol. 2 No. 2 (2025): YARSI DENTAL JOURNAL
Publisher : Lembaga Penelitian Universitas YARSI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33476/ydj.v2i2.246

Abstract

Background: Human Immunodeficiency Virus (HIV) is a type of virus that attacks white blood cells and causes a decrease in the human immune system. The route of HIV transmission can be through sexual intercourse, shared syringe use, transmission through the placenta from HIV-positive mothers to children, and transfusion of blood infected with the virus. According to WHO data, about 39 million people are infected with HIV by the end of 2022. Oral manifestations are the initial symptoms in 30-80% of HIV-infected people and can be used to detect HIV/AIDS early. Objective: This study aims to identify oral clinical finding in HIV/AIDS patients at oral disease clinic of RSUD Kota Tangerang. Methods: This research was descriptive analysis using cross- sectional study design from 97 electronic medical records of HIV/AIDS patients at the Oral Medicine Clinic of RSUD Kota Tangerang. The data collected included the diagnosis of oral cavity findings. Results: The results showed that the three highest percentages related to oral manifestations found were chronic gingivitis (26.7%), then oral candidiasis (21.1%), coated tongue (16.2%), cheilitis (9.7%) and apthous like ulcer (6.5%). Conclusion: In HIV/AIDS patients at the Oral Medicine Clinic, there are many oral manifestations that vary.
Co-Authors Ahmad Fadli Amun Amri Mersil, Sarah Miyuri Areta