The Nuclear Medicine Building is a strategic healthcare facility that utilizes open radiation sources for diagnosis and treatment. Due to its high structural complexity and radiological risks, this study aims to analyze the construction management implementation of the Nuclear Medicine Building project at Dr. Soedarso Regional General Hospital, Pontianak. The research utilizes primary data from field observations and secondary data from project documents, analyzed through four critical aspects: cost, time, quality, and human resources. The study produces an Implementation Budget Plan (RAP) totaling IDR 7,904,689,106.53. Time management planning establishes a project duration of 15 weeks or 108 calendar days, utilizing Network Planning and Bar Charts to monitor the critical path. Quality management is implemented through a quality control table to ensure technical specification compliance, while human resource planning identifies a peak labor requirement of 100 workers per day during the 7th week. Analytically, the integration of cost and time in this project validates the "Iron Triangle" theory, where precision in substructure work (foundations) serves as the primary determinant of schedule success due to the specialized loading requirements of nuclear facilities. These findings suggest that for specialized medical infrastructure, radiation safety standards demand more stringent productivity coefficients compared to general building projects. The academic implication of this research indicates that the application of national AHSP regulations (PUPR No. 8 of 2023) requires adjustment for site-specific risk variables in high-hazard buildings to prevent deviations between technical planning and field reality. These results contribute to the project management literature on the necessity of integrated frameworks in enhancing the resilience of regional medical referral infrastructure.