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All Journal Medula Jurnal Ilmu Kedokteran dan Kesehatan
Retno Ariza
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Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Journal : Medula

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Kolaborasi Tuberculosis (TBC) dan Human Immunodeficiency Virus (HIV) Yona Arisena Magdalena Silitonga; Intanri Kurniati; Retno Ariza; Mukhlis Imanto; Jhond Fatriyadi S
Medula Vol 9 No 2 (2019): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v9i2.269

Abstract

Tuberculosis (TBC) is becoming one of the highest causes of death in the world. Tuberculosis is caused by Mycobacterium tuberculosis that is transmitted via droplet originating from tuberculosis patients. It is estimated that one-third of people in the world have been infected by tuberculosis, but only 10-20% of people will show the symptoms. Symptoms that can arise in tuberculosis are such as bleeding cough, weight loss, night sweats, chest pain, shortness of breath and weakness. Meanwhile, human immunodeficiency virus (HIV) is a retrovirus-famili because of its ability to convert the RNA genome into DNA. HIV transmission occurs due to the entry of this virus into the body through body fluids of people who are already infected by HIV. Both of these infectious diseases alike because both of them can cause a decrease in immune system activities in the body of the sufferer. Collaboration of both diseases is common and is a deadly combination because it interacts with each other in all aspects of the disease, ranging from pathogenesis, epidemiology, clinical manifestations, treatment and prevention. Tuberculosis is also a leading cause of death in HIV-positive patients. In 2016 in Indonesia, there are found 360,565 cases of TBC, with 14% of them are also known to suffer from HIV-positive. The results of the study suggest that there is a mutual relationship between the two diseases in causing a clinical symptoms through decreased activity of the body's immune system.
Hubungan Ketepatan Teknik Penggunaan Inhaler Dengan Hasil Uji Spirometri Pada Pasien Asma Di Klinik Harum Melati Dan RSU Wisma Rini Kabupaten Pringsewu Retno Ariza; Fransisca Sinaga; Jordy Oktobiannobel; Siti Fatima Az Zahra
Medula Vol 12 No 2 (2022): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v12i2.343

Abstract

Asthma is a heterogeneous disease with chronic airway inflammation that still be a concern in the world. GINA 2021 explain that if asthma patients are not continuously controlled, it is necessary to review common problems that frequently found, one of which is the wrong inhaler technique. The incorrect of inhaler techniques will have an effect on drug delivery to the lungs which affects the success of therapy and improvement of lung function. To determine the relationship between the accuracy of inhalers technique with the results of the spirometry test in asthmatic patients.This study used a quantitative research with an analytical survey method and a cross-sectional study approach. The study was conducted by observation to see the correlation between the accuracy of the inhaler technique and the results of the spirometry test with parameters FEV1. Sampling was carried out at the Harum Melati Clinic and Wisma Rini Hospital, Pringsewu. There were 173 asthma patients that using inhaler, but only 103 samples met the inclusion criteria, namely patients aged >5 years who used inhalers and taken spirometry examinations. In this study, the inhaler accuracy test was carried out using a checklist 2 times where the first was carried out before education of inhalers technique and the second was carried out after education. Spearmen correlation test showed that there was no relationship between inhaler technique and FEV1 before education (p-Value 0.941; p>0.05), but there is a significant relationship between the technique of using the inhaler with the results of FEV1 after education (p-Value 0.049; p < 0.05).
Co-Authors Fransisca Sinaga Hidayat Hidayat Ian Ibnu Faizal Intanri Kurniati Jhons Fatriyadi Suwandi Jordy Oktobiannobel Mala Kurniati Mukhlis Imanto Siti Fatima Az Zahra Yona Arisena Magdalena Silitonga