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All Journal Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Bhakti Sabha Nusantara Journal of Health Research and Technology
Astiah, Andi Asda
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Dentistry Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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PERBANDINGAN EFEKTIVITAS ANTARA JUS WORTEL DAN AIR KELAPA HIJAU TERHADAP TINGKAT DISMENOREA PADA MAHASISWA ASRAMA PUTRI UNIVERSITAS BATAM Hajiansyah, Abdelzikri; Astiah, Andi Asda; Isramilda, Isramilda
Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam Vol 14 No 1 (2024): Zona Kedokteran: Program Studi Pendidikan Dokter Universitas Batam
Publisher : Universitas Batam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37776/zked.v14i1.1377

Abstract

Background: Dysmenorrhea, or menstrual pain, is a common complaint experienced by women during menstruation. Factors such as dietary patterns and consumption of specific beverages can play a role in reducing the severity of dysmenorrhea. One such beverage with the potential to alleviate menstrual pain is carrot juice and green coconut water, both rich in nutrients and anti-inflammatory compounds. Hence, it is crucial to investigate the comparison between carrot juice and green coconut water regarding the severity of dysmenorrhea. Methods: This study utilized a Quasi-Experimental research design with a Non-equivalent approach. The research was conducted at the Female Dormitory of Batam University from November 2023. The sampling technique used was Simple Random Sampling, with a total sample size of 42 or 14 sample in each group. Results: Based on the One-Way ANOVA test, the obtained result indicates that the significance value of the ANOVA test (Sig.) is 0.000 (< 0.05). Therefore, it can be concluded that there is a significant difference between the effects of carrot juice and green coconut water on the reduction of dysmenorrhea levels. Conclusion: Based on the research findings, it can be concluded that the intervention of green coconut water is more effective in reducing menstrual pain compared to the intervention of carrot juice among female dormitory students University of Batam in 2023.
Improving Maternal Health Literacy Through Educational Intervention On Pregnancy Danger Signs: A Pre-Post Study In Batam, Indonesia: Peningkatan Literasi Kesehatan Ibu Hamil Melalui Intervensi Edukasi Tentang Tanda Bahaya Kehamilan: Studi Pre-Post Di Batam, Indonesia Prihadianto, Dino Gagah; Astiah, Andi Asda; Romiana, Dwi
Bhakti Sabha Nusantara Vol. 4 No. 1 (2025): Bhakti Sabha Nusantara
Publisher : Sahabat Publikasi Kuu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58439/bsn.v4i1.396

Abstract

Background: Maternal Mortality Rate (MMR) and Infant Mortality Rate (IMR) in Indonesia remain high and pose significant challenges in achieving the Sustainable Development Goals (SDGs) 2030. One of the contributing factors is the low awareness among pregnant women regarding the danger signs of pregnancy. This community service activity aimed to improve maternal health literacy through structured education on pregnancy danger signs at Tridi Clinic, Batam. Methods: The intervention involved 60 pregnant women and employed pre-test and post-test assessments, lectures, group discussions, demonstrations, and the distribution of educational materials. Data were analyzed using descriptive statistics and the percentage increase in knowledge. Results: A significant improvement was observed in participants’ knowledge, with scores increasing from 52.3% in the pre-test to 83.7% in the post-test. The educational methods used proved effective, supported by participants’ motivation, health facility support, and the competence of the facilitator team. Conclusion: Structured education on pregnancy danger signs effectively enhances pregnant women's knowledge. Similar programs should be replicated regularly to support efforts in reducing maternal and infant mortality in Indonesia.
Oxidative Stress And Redox-Based Interventions In Chronic Diseases: A Systematic Review astiah, andi asda
Journal of health research and technology Vol. 3 No. 2 (2025): Journal of health research and techonology
Publisher : Sahabat Publikasi Kuu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58439/jhrt.v3i2.399

Abstract

Background:Oxidative stress, characterized by an imbalance between reactive oxygen species (ROS) production and antioxidant defense systems, has emerged as a critical factor in the pathogenesis of various chronic diseases. Understanding its mechanisms and therapeutic implications is essential for developing effective interventions. Objective:This review aims to evaluate the role of oxidative stress in chronic diseases and to analyze the efficacy of pharmacological interventions with antioxidant or pro-oxidant properties across cardiovascular, metabolic, neurodegenerative, and oncological disorders. Methods:A systematic search was conducted across PubMed, Scopus, and Web of Science for articles published between January 2000 and December 2024. Inclusion criteria encompassed original studies (RCTs, observational, and preclinical) examining oxidative stress biomarkers and therapeutic outcomes. Quality assessment employed validated tools including the Cochrane Risk of Bias Tool, Newcastle-Ottawa Scale, and AMSTAR-2. A narrative synthesis approach was used due to heterogeneity in study designs. Results:Malondialdehyde (MDA) and 8-hydroxy-2'-deoxyguanosine (8-OHdG) were the most consistently elevated markers across diseases such as type 2 diabetes mellitus, cardiovascular disease, Parkinson’s disease, COPD, psoriasis, and chronic kidney disease. Antioxidant enzymes—superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH)—were frequently reduced, indicating compromised redox defense. MDA and SOD levels were responsive to lifestyle or pharmacological interventions, highlighting their potential for therapeutic monitoring. Heterogeneity in biomarker assessment methods limited cross-study comparisons. Conclusion:Oxidative stress biomarkers demonstrate consistent alterations across chronic diseases, suggesting their utility in disease monitoring and risk stratification. MDA, 8-OHdG, SOD, and CAT are among the most clinically informative markers. Standardized measurement protocols are essential to improve their translational value in redox-based diagnostics and therapeutic evaluation
Co-Authors Hajiansyah, Abdelzikri Isramilda, Isramilda Prihadianto, Dino Gagah Romiana, Dwi