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All Journal Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) Idea Pengabdian Masyarakat Sinteza
Okzelia, Sari Defi
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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Formulation of Micellar Based Water from Piper crocatum Leaves Extract Using Various Concentrations of Poloxamer 188: Formulasi Micellar Berbasis Air Ekstrak Daun Sirih Merah (Piper crocatum) dengan Variasi Konsentrasi Poloxamer 188 Pratiwi, Hani; Okzelia, Sari Defi; Afiah, Mawar
Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) Vol. 10 No. 2 (2024): (October 2024)
Publisher : Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/j24428744.2024.v10.i2.16628

Abstract

Background: Micellar based water (micellar water) is a preparation used to clean the face or makeup with water-based ingredients. Micellar water has moisturizing additives accompanied by antioxidants. Piper crocatum leaves is one of the plants that contain flavonoid compounds so it has the potential as an antioxidant. Micelles are the main component in micellar water preparations derived from amphiphilic block copolymer-type surfactants such as poloxamer. Objectives: The purpose of this study was to formulate, evaluate, and observe the antioxidant activity of the most optimum formulation of micellar based water preparations of Piper crocatum leaves extract with variations in poloxamer 188 concentrations. Material and Methods: The stages of this research were material preparation, extract characteristics evaluation, production of micellar preparations at poloxamer 188 concentrations of 1% (F1); 1.5% (F2); and 2% (F3); preparation characteristics evaluation, stability, particle size, antioxidant activity assay for the optimum formula, and irritation test. Results: The results of the evaluation showed that the pH of the preparation ranged from 4.54 - 4.76; viscosity values ranged from 16.40 - 24.26 cP; particle size ranged from 170.6 – 349.9 nm; and the entire formula did not irritate the skin. Conclusions: Based on the results of this study, it was found that the most optimal concentration of poloxamer 188 was 2% (F3) with IC50 value of 119.63 ppm which categorized as a moderate antioxidant activity.
Edukasi Dapatkan, Gunakan, Simpan dan Buang (DAGUSIBU) Obat pada Masyarakat Secara Home Pharmacy Care Yanti, Silfera Indra; Rohenti, Iin Ruliana; Okzelia, Sari Defi; Shoaliha, Maratun
Idea Pengabdian Masyarakat Vol. 4 No. 02 (2024): May
Publisher : PT.Mantaya Idea Batara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53690/ipm.v4i02.284

Abstract

DAGUSIBU (DApatkan, GUnakan, SImpan, BUang) obat yaitu tatacara pengunaan dan pengelolaan obat secara baik dan benar. Ketidaktahuan masyarakat dalam mengelola obat bisa dipengaruhi oleh pengetahuan, perilaku dan sikap. Kegiatan edukasi bertujuan memberikan pemahaman masyarakat dalam penggunaan obat dan untuk mengetahui tingkat pengetahuan, sikap dan perilaku terkait DAGUSIBU di kecamatan Duren Jaya dan masyarakat sekitar TPS Bantar Gebang Kota Bekasi yang dilakukan secara Home Pharmacy Care pada 55 responden dan pemberian kuesioner untuk mengidentifikasi tingkat pemahaman, perilaku dan sikap masyarakat mengenai DAGUSIBU. Hasil pengabdian tentang pengetahuan, sikap dan perilaku tentang DAGUSIBU adalah baik tetapi masih ada masyarakat yang kurang memahami cara mendapatkan obat, penggunaan antibiotik dan cara pembuangan obat. Dengan kegiatan ini nantinya dapat meningkatkan pengetahuan masyarakat dalam penggunaan obat sehingga perilaku dan sikap masyarakat tentang DAGUSIBU menjadi baik dan benar.
Formulasi Sabun Cair Cuci Tangan dan Uji Aktivitas Bakteri Staphylococcus aureus dari Ekstrak Daun Kelor (Moringa oleifera Lam.) Waris, Dinda Izzatul; Yanti, Silfera Indra; Okzelia, Sari Defi; Amirulah, Fajar
Sinteza Vol. 3 No. 1 (2023): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v3i1.7890

Abstract

Soap is what can be used to wash hands so as to avoid bacteria that can cause diseases such as acne and boils. One of the natural ingredients in making soap is Moringa leaves. Moringa leaves are one of the plants that have antibacterial properties, Staphylococcus aureus bacteria are bacteria that can cause infectious diseases such as acne and boils. The purpose of this study was to formulate hand washing liquid soap from Moringa leaf extract (Moringa oliefera Lam.), to evaluate the antibacterial activity of the preparation against Staphylococcus aureus. Moringa extract was obtained by maceration method. Furthermore, phytochemical screening was carried out, then formulated into soap preparations at concentrations of 20% (F1), 25% (F2), and 30% (F3). The preparations were evaluated and tested for activity against Staphylococcus aureus. Based on the results of the study, the yield of ethanol extract of Moringa leaves was 32.35% and contained secondary metabolites such as alkaloids, flavonoids, saponins and tannins. Moringa leaf ethanol extract soap formula met the requirements of all test parameters including pH test, irritation test, specific gravity test, and organoleptic test. The results of the antibacterial activity test gave an inhibition zone of 20.2 mm, 21.5 mm, and 23.2 mm, respectively. For F1, F2 and F3 against Staphylcoccus aureus.
Co-Authors Afiah, Mawar Fajar Amirulah Maratun Shoaliha Pratiwi, Hani Rohenti, Iin Ruliana Waris, Dinda Izzatul Yanti, Silfera Indra