Tuberculosis (TB) is a global health issue exacerbated by social, cultural, and economic factors such as stigma, limited access, and challenging economic conditions, which lead to poor treatment adherence. Digital transformation in nursing through telemedicine, telenursing, and mHealth has emerged as a solution to improve patient monitoring and clinical outcomes. A literature review using the PRISMA-ScR approach was conducted to identify studies on the role of digital technology in enhancing healthcare quality for TB patients. Data were collected from Google Scholar, ResearchGate, and Mendeley with inclusion criteria for the years 2021–2025. Analysis of 12 articles revealed that digital interventions, including telenursing via SMS/WhatsApp, mHealth applications, and electronic monitoring systems, effectively improve treatment adherence and patient monitoring. mHealth apps provide medication reminders and health education, while digital systems allow real-time monitoring by healthcare providers. Digital transformation significantly contributes to improving treatment adherence and healthcare quality for TB patients, although challenges such as technology access, digital literacy, and infrastructure remain. Supportive policies for digital access and literacy, along with the development of inclusive and sustainable technological strategies, are essential for optimizing TB treatment and advancing TB elimination efforts. Keywords: Telenursing, Tuberculosis, Medication Adherence, mHealth Applications, Treatment Compliance.