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All Journal Journal of Community Empowerment for Health Ophthalmologica Indonesiana
Krisna Dwi Purnomo Jati
Department Of Ophthalmology, Faculty Of Medicine, Public Health, And Nursing, Universitas Gadjah Mada, Yogyakarta, Indonesia; Ophthalmology Clinic, Dr. Sardjito General Hospital, Yogyakarta, Indonesia
Education Health Professions Medicine & Pharmacology Nursing Public Health

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INTRAOPERATIVE MITOMYCIN-C, 5-FLUOROURACIL, RETROBULBAR TRIAMCINOLON ACETONIDE, IS IT EQUALLY EFFECTIVE TO DECREASE INTRA OCULAR PRESSURE AFTER TRABECULECTOMY? Sari, Yessi Primanda; Ekantini, Retno; Gani, Tatang Talka; Jati, Krisna Dwi Purnomo
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/4e85px09

Abstract

Introduction & ObjectivesTo evaluate the effect of mitomycin-C (MMC), 5-fluorouracil (5-FU), and retrobulbar triamcinoloneacetonide (TA) on the surgical result of trabeculectomy. MethodsAll consecutive trabeculectomies with releasable sutures performed in Sardjito General Hospitalbetween January 2022 and December 2022 were retrospectively reviewed from medical records.Patients without any intraoperative metabolite (control group, n=5) were compared to those withretrobulbar TA (n=5), MMC group (n=19), and 5-FU group (n=11) in terms of surgical success.Successful surgery results were defined as IOP between 5 - 21 mm Hg without any furthermedications or surgical intervention and fewer complications. Results40 eyes of 35 patients (15 male, 25 female, mean age 52.4 years) were included in the study. Patientwas observed until post-operation day (POD) 90. There were no significant differences of intraocularpressure at POD 1, 7, 30, 60, and 90 between control group compared to TCA, MMC, and 5-FUgroup. Intraocular pressure pre- and post-operation in each group was significantly different(p<0.05). The lowest mean intraocular pressure of POD 90 was in 5-FU group (13.64 ± 4.08).Complication after trabeculectomy in TCA group was 21%, MMC group was 27%, 5-FU group was10%, and control group was 42%. ConclusionMMC, 5-FU, and TCA in this study are equally effective to decrease IOP after trabeculectomy.
Relationship Between Mean Deviation Slope with Related Risk Factors and Foveal Sensitivity of Humphrey Field Analyzer Test in Open Angle Glaucoma: Oral Presentation - Observational Study - Resident Rizki, Hanis Fatkhul; Gani, Tatang Talka; Ekantini, Retno; Jati , Krisna Dwi Purnomo
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/hcfjcs46

Abstract

Introduction & ObjectivesTo analyze relationship between mean deviation (MD) slope with related risk factors and fovealsensitivity of Humphrey field analyzer (HFA) in open angle glaucoma. Patient and MethodsThis study was retrospective and consecutive sampling during a year follow up period in SardjitoGeneral Hospital. A total 95 eyes from 95 patient were exemained the MD slope by HFA (SITAstandard, 24-2 program) being follow up and compared first examination with the final VF test.Relation of MD slope with risk factors and HFA parameters were correlatively analyzed. ResultsMean Deviation slope was observed in 48/95 patients (50.52 %) and no progression was observed in47/95 patients (49.47 %). The related risk factors gender, age, spherical equivalent and IOP do notshowed significant correlation with MD slope (R= 0.02, P= 0.89), (R=0.10, p=0.47), (R=-0.27, p=0.06) and (R=-0,13, p= 0.35). Foveal sensitivity test in HFA parameter do not showed significantcorrelation with MD slope (R= 0.14, p=0.32). ConclusionWorsening value of spherical equivalent and IOP showed negative correlation to MD slope, butstatistically do not showed significant correlation caused there are not much differences betweenprogress and non progress group.
Co-Authors Agung Saputro Aloysius Angga Wibowo Anindita Dianratri Ekantini, Retno Gani, Tatang T Gani, Tatang Talka Hartono Hartono Jehan Fauzi Jehan Muhammad Raditya Fadhil Fadhil Rahma An Nazzila, Meta Retno Ekantini Rizki, Hanis Fatkhul Saputra, Yuandani Sari, Yessi Primanda Suhardjo Suhardjo Supanji Supanji Tania Purbonegoro Tatang Talka Gani Wardhana, Arif Kusuma