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Case Study of Impact and Risk Factors of Brucellosis (Brucella abortus) in Beef Cattle Bagenda, Isnaniah; Malaka, Ratmawati; Muflihanah; Nurul Waqiah, Syarifah; Mohamed Yousof, Sadam Suliman
Hasanuddin Journal of Animal Science (HAJAS) Vol. 5 No. 2 (2023)
Publisher : Faculty of Animal Science, Hasanuddin University, Makassar, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/hajas.v5i2.27634

Abstract

Bovine Brucellosis is endemic in Polewali Mandar Regency with a prevalence above 2%. Control programs implemented through active and passive surveillance, public awareness of the impact of the disease, and tests and slaughter have not been able to reduce the prevalence rate. This study aimed to examine the impact and risk factors of brucellosis on the productivity of beef cattle in Polewali Mandar Regency. A total of 100 primary data from cattle farmers related to brucellosis were used in this cross-sectional study. Descriptive analysis was employed to determine the parameters that were important in the occurrence of brucellosis. To establish risk factors, a univariate logistic regression analysis was carried out and revealed that odds of infection were significantly higher in history of abortion (OR = 11.82, 95% CI: 4.08 - 34.19,   p < 0.001) and in gestational age (OR = 0.0214, 95% CI: 0.0063 - 0.0724, p < 0.001) and in dry season than wet season (OR = 14.89, 95% CI: 4.97 - 44.62, p < 0.001).  The brucellosis control program through mass vaccination must immediately become a recommendation for regional and central governments to reduce brucellosis transmission to prevent economic impacts and losses for farmers, particularly the public health risk. Keywords: brucellosis, beef cattle, impact, risk factor, productivity
Pathogenicity and Classification of Influenza A Virus in poultry isolates from Sulawesi in 2018 Mutisari, Dewi; Muflihanah; Ferra Hendrawati; Lestari; Hendra Wibawa
Jurnal Riset Veteriner Indonesia (Journal of The Indonesian Veterinary Research) VOLUME 7, No 2, JULY 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/jrvi.v7i2.22039

Abstract

Avian influenza (AI) is a viral infection caused by the Influenza virus type A. Infection with the Avian Influenza Virus (AIV) has resulted in major financial losses in the cattle industry as well as substantial public health consequences. Indonesia has been dealing with an HPAI H5N1 outbreak since 2003. Despite the implementation of many prevention and control measures, the AIV disease continues to spread. Three Sulawesi isolates were submitted to whole-genome sequencing (WGS) in 2018 using the Illumina next generation sequencing (NGS) technology. The BioEdit 7 molecular analysis application was used to do multiple alignments and amino acid prediction. The Influenza Research Database's Highly Pathogenic H5N1 Clade Classification Tool (https://www.fludb.org) was used for clade analysis. One of the virus's pathogenicity is the amino acid cleavage site in the hemagglutinin (HA) gene. We concluded that the PQRERRRK-GLF amino acid motif was present in the cleavage site of the HA gene in avian AIV isolates from Sulawesi in 2018. This indicates that the AIV virus isolates are pathogenic and highly virulent avian influenza viruses (HPAI). Clade analysis revealed that the AIV isolates were from the H5N1 virus clade 2.3.2.1c.