Reyaan, Irianti Bahana Maulida
Department Of Pharmacology And Clinical Pharmacy, School Of Pharmacy Institut Teknologi Bandung

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Pemanfaatan Tumbuhan Bersifat Laksatif dan Prokinetik untuk Konstipasi Vanessa Claudia Wiharja; Elin Yulinah Sukandar; Irianti Bahana Maulida Reyaan
Acta Pharmaceutica Indonesia Vol. 46 No. 2 (2021)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/api.v46i2.16923

Abstract

Konstipasi merupakan suatu kondisi yang ditandai oleh perubahan konsistensi feses menjadi keras, ukuran tinja besar, dan penurunan frekuensi defekasi. Laksatif dan prokinetik digunakan dalam penanganan konstipasi. Banyak tumbuhan yang memiliki efek tersebut sehingga dapat dimanfaatkan untuk mengatasi konstipasi. Penelitian ini menggunakan data-data dari artikel yang ditemukan pada mesin pencari mulai dari 1 Januari 2010 hingga 29 Maret 2021. Dari hasil pencarian, ditemukan 93 tumbuhan yang telah di uji secara praklinik dan klinik. Tumbuhan dengan efek laksatif dan prokinetik yang potensial antara lain Allium mongolicum Regel., Ipomoea nil (L.) Roth., Carissa carandas L., Linum usitatissimum L., Prunus mume (Siebold) & Zucc., Piper nigrum L., Cucumis melo L., Eugenia dysenterica DC., Opuntia ficus-indica (L.) Mill., Cassia fistula L., Rosa damascena Herrm., dan Senna alexandrina Mill. dengan berbagai mekanisme kerja. Tumbuhan yang dibahas dalam studi ini diharapkan dapat digunakan untuk terapi alternatif, pengembangan senyawa baru dan pembuatan obat-obatan baru untuk mengatasi konstipasi.  
Studi Potensi Interaksi Obat pada Resep Polifarmasi di Dua Apotek Kota Bandung Irianti Bahana Maulida Reyaan; Cempaka Kuning; I Ketut Adnyana
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 11, No 3
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.56931

Abstract

Polypharmacy prescription very commonly occurs on patient’s prescription in every health facilities. Polypharmacy may increase the risk of Drug-drug Interactions (DDI’s) which mostly causes harm impact in the patient’s therapy. Drug interactions considered clinically significant if it increases the toxicity or decreases the effectiveness of therapy. The objective of this study was to analyze the potential drug interactions in polypharmacy prescriptions in two pharmacy at Bandung city in general, based on the severity, and mechanism. This study was a non-experimental study that was carried out retrospectively by taken prescription data that received by two Pharmacies in Bandung City for the period of October- December 2018. Samples were obtained by purposive sampling technique and were analyzed by using Stockley’s Drug Interaction 9th Edition and database such as micromedexsolutions.com to determine the potential for drug interactions based on its severity and mechanism of interactions. A total of 1218 prescriptions were analyzed,  of which 896 prescription  (73.56%) were included in the inclusion criteria, and 569 prescription (63.50%) had potential drug-drug interactions. Based on the severity, majority of drug-drug interaction is moderate (85.60%), followed by minor interactions (9.28%), and major interactions (5.12%). Based on the mechanism, majority of drug-drug interactions is pharmacodynamic interactions (90.34%), and followed by pharmacokinetic interactions (9.66%). Based on the many of potential drug interactions, polypharmacy prescribing should be avoided and management of potential DDI’s should be performed.
EVALUASI PENGETAHUAN MAHASISWA FARMASI DAN MASYARAKAT UMUM TERKAIT PENGGUNAAN SUPLEMEN PADA COVID-19 Reyaan, Irianti Bahana Maulida; Dwiyanti, Jessica; Damayanti, Sophi
Acta Pharmaceutica Indonesia Vol. 49 No. 01 (2024)
Publisher : School of Pharmacy Institut Teknologi Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5614/api.v49i01.23613

Abstract

COVID-19 adalah penyakit yang disebabkan oleh virus SARS-CoV-2. Selain obat, banyak penelitian yang juga dilakukan untuk menentukan efikasi serta keamanan suplemen untuk COVID-19, misalnya vitamin C, vitamin D, dan zink yang memiliki peran bagi sistem kekebalan tubuh termasuk potensiasi efek antivirus. Pengetahuan dan penggunaan suplemen yang tepat dapat menjadi salah satu upaya untuk menunjang pengobatan COVID-19. Survei dengan menggunakan kuesioner merupakan metode yang dapat dipilih untuk mendapatkan gambaran pengetahuan mahasiswa farmasi dan masyarakat umum terkait hal tersebut. Tujuan penelitian ini adalah menentukan tingkat pengetahuan mahasiswa farmasi dan masyarakat umum terkait suplemen dan penggunaannya dalam kondisi COVID-19. Survei dilakukan pada 412 responden yang terdiri dari mahasiswa farmasi dan masyarakat umum pada bulan Januari 2021-April 2021. Hasil survei dari 412 responden menunjukkan bahwa pengetahuan mahasiswa farmasi dan masyarakat umum terkait suplemen dan penggunaannya untuk COVID-19 masih kurang dengan 18,4% mahasiswa farmasi dan 4,5% masyarakat umum berada pada kategori pengetahuan tinggi. Berdasarkan analisis, tingkat pengetahuan mahasiswa farmasi lebih baik dari masyarakat umum terkait penyakit COVID-19, penggunaan suplemen secara umum, dan penggunaan suplemen untuk COVID-19 (p<0,001).
Dampak Intervensi Edukasi dan Aplikasi Pengingat Minum Obat terhadap Pengetahuan dan Kepatuhan Pasien Tuberkulosis Paru di Puskesmas di Kota Bandung Reyaan, Irianti Bahana Maulida; Faustincia, Ivena; Zazuli, Zulfan
JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Vol 13, No 4
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jmpf.88408

Abstract

Tuberculosis (TB) patient compliance with ongoing therapy and knowledge regarding TB has an impact on the cure rate. Despite implementing various strategies, the prevalence of TB in Indonesia remains high, and the success rate of its treatment is still below the global average, potentially leading to continued transmission of TB within the community. This study aims to determine the improvement of knowledge and compliance among pulmonary TB patients following an intervention involving education and the use of a medication reminder application in two community health centers in the city of Bandung. The research design was experimental, where 29 subjects recruited were randomized into two groups: one group receiving additional education and introduction to the mobile application (Jadwal Minum Obat), and the other group receiving only counseling at the health centers. Primary data that was collected include baseline test scores and final test scores of subjects based on the KATUB-Q questionnaire. Patient compliance was assessed using the self-assessment method with the MARS-5 questionnaire and the pill count method. The subjects' experiences in the intervention group while using the mobile application were also documented. A total of 16 subjects completed the study. The education method and medication reminder application used in this study have not significantly improved the knowledge and compliance of pulmonary TB patients in taking their medication (p > 0.05). However, percentage of consumed medication compared to the prescribed medication in the intervention group higher than the control group (87.4 ± 4.8% vs 78.8 ± 8.3%). Subjects found the application useful, though there were still some shortcomings. Further research with a larger sample size using an improved medication reminder application is needed.