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ANALYSIS OF THE EFFECTIVENESS OF NATURAL INGREDIENTS IN ANTHYPERURICEMIA:REVIEW Angela, Elva; Susanti; Diniatik
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 10 No 3 (2025)
Publisher : Universitas Muhammadiyah Ahmad Dahlan Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v10i3.1322

Abstract

Introduction: Hyperuricemia is characterized by increased uric acid levels in the blood due to excessive production or impaired excretion. In Indonesia, the hyperuricemia rate reaches 18% of the total population. Objective: This study aimed to explore and analyze the potential of medicinal plants with antihyperuricemic activity in reducing uric acid levels in patients with hyperuricemia and experimental animals. Materials and Methods A total of 21 scientific articles were reviewed, focusing on the treatment of hyperuricemia using natural ingredients. Data were obtained from the Google Scholar and PubMed databases using keywords such as “hyperuricemia,” “medicinal plants,” and “natural therapy.” The inclusion criteria were articles published within the last 10 years that involved in vitro and in vivo models.  Results: The review identified several natural ingredients, including turmeric, kepel leaves, and mangosteen peel, which demonstrated significant antihyperuricemic effects. These ingredients were effective in reducing uric acid levels in both animal and human studies.Conclusion: Natural ingredients show promising potential as alternative treatments for hyperuricemia by inhibiting xanthine oxidase activity. However, further clinical trials are required to validate these findings and support their application in therapeutic practice. Keywords: Antihyperuricemia, Uric Acid, Natural Ingredients, Clinical Trials
Pengaruh Waktu Fermentasi Madu dengan Bawang Putih Tunggal (Allium sativum L.) terhadap Daya Hambat Bakteri Propionibacterium acnes Angela, Elva; Kunaedi, Aan; Ine Suharyani; Andriana, Andriana
Sci-tech Journal Vol. 1 No. 1 (2022): Sci-tech Journal (STJ)
Publisher : MES Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56709/stj.v1i1.25

Abstract

Honey is a substrate that has widely used by the people of Indonesia for treatment, one of which is used to treat acne. Honey has antimicrobial inhibitory power, antimicrobial ability is also found in other natural ingredients, one of it is Single Garlic (Allium sativum L.). Community trend towards the two natural ingredients, one of which is by combining Honey and Single Garlic (Allium sativum L.) using the method of soaking Single Garlic (Allium sativum L.) in Honey. The purpose of the study is to determine the inhibitory power of honey bacteria from soaking / fermentation against propionibacterium acnes bacteria.Testing use the disc paper diffusion method with a sample of fermented Honey and a single Garlic (Allium sativum L.) against the length of honey fermentation time, positive control (Clindamycin 300 mg), and negative control (aquadest). Sample Honey and Garlic Sample (Allium sativum L.) were fermented length time at weeks 1,2,3 and 4. The results showed that the length of time honey fermentation can increase the inhibitory power of the growth of Propionibacterium acnes bacteria by the presence of clear zones around the disc paper. The diameters of honey fermentation in weeks 1,2,3 and 4 are 0.416 mm, 0.65 mm, 0.775 mm and 1.8 mm. The conclusion that the length of fermentation time of Honey and Single Garlic (Allium sativum L.) will increase in diameter in the clear zone of its inhibitory power known in the fourth week to have a maximum inhibitory power of 1.8 mm. Keywords: Fermented honey, Single Garlic,Inhibitory power of bacteria Propionibacterium acnes
Pemberdayaan kesehatan masyarakat Desa Gunung Manik Melalui Potensi Desa Budidaya Madu: Empowerment of community health in Gunung Manik Village through the Village Potential of Cultivating Honey Kunaedi, Aan; Lestari, Trisna; Johan, Johan; Utami, Arie Susetio; Prasetyo, Tri Budi; Andriana, Andriana; Angela, Elva
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 8 No. 6 (2023): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v8i6.5412

Abstract

The abundant natural potential of Gunung Manik has not been optimally utilized. The support of the village apparatus to continue to improve village welfare makes the development of villages and residents quite fast in receiving positive information from outside. Natural potential can be further optimized, one of which is by developing honey cultivation, which has great potential with the support of available natural resource conditions. Activities are carried out using counseling methods and interactive directly to measure the level of pre-activity knowledge and understanding in the people of Gunung Manik Village, descriptive material presentation through interactive so that the implementation of activities is more active and avoids boredom. The results of the activity can be seen from increasing community insight into health, That is benefits of honey on health and the enthusiasm of community for honey cultivation as an effort to improve the economy and health of the people of Gunung Manik Village, Ciniru Kuningan.
Penyuluhan tentang “Manisnya Madu Penuh Manfaat” kepada Anak-Anak Santana, Salma Audhita; Maesaroh, Thia Fitri; Angela, Elva; Andriana; Kunaedi, Aan
Jurnal SOLMA Vol. 12 No. 1 (2023)
Publisher : Universitas Muhammadiyah Prof. DR. Hamka (UHAMKA Press)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22236/solma.v12i1.10556

Abstract

Background: Penyuluhan merupakan kegiatan menyebarluaskan hal baru agar masyarakat tertarik dan bersedia menerapkan dalam kehidupan sehari-hari. Saat ini, masih banyak orang yang menganggap bahwa madu hanya bermanfaat sebagai pemanis sehingga tingkat konsumsi madu di Indonesia tergolong rendah. Penyuluhan ini bertujuan untuk meningkatkan pengenalan madu sekaligus mendorong masyarakat, khususnya dimulai dari segmen anak-anak tentang pemahaman madu akan manfaat mengkonsumsi rutin madu. Metode: Kegiatan dilaksanakan di Graha Yatim & Dhuafa Yayasan Robbani, Kecamatan Kesambi, Kota Cirebon, Jawa Barat. Jumlah anak yang mengikuti kegiatan ini sebanyak 16 orang. Pelaksanaan kegiatan dilakukan dengan 3 tahap yaitu tahap observasi, tahap edukasi, dan tahap evaluasi. Hasil: Hasil penyuluhan terlihat pada saat tahap evaluasi dimana anak-anak dapat menjawab pertanyaan pemateri dengan baik. Pada saat penyampaian materi, peserta memberikan respon dengan sangat antusias karena materi yang disampaikan dikemas sedemikian rupa agar mudah dipahami oleh anak-anak. Kesimpulan: Penyuluhan ini dapat meningkatkan pengetahuan anak-anak tentang pentingnya mengonsumsi madu bagi kesehatan.