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All Journal E-Jurnal Medika Udayana Nusantara Medical Science Journal
Syakri Syahrir
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Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience

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The Effectiveness Between Tamsulosin and Solifenacin Combined with Tamsulosin on Treatment of Ureteral Stent-Related Symptoms Berry Erida Hasbi; Muhammad Asykar Palinrungi; Khoirul Kholis; Syarif Bakri; Syakri Syahrir; Firdaus Kasim
Nusantara Medical Science Journal Volume 6 Issue 1, January - June 2021
Publisher : Faculty of Medicine, Hasanuddin University.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/nmsj.v6i1.14263

Abstract

Introduction: The clinical usage of the ureteral stent caused several stent-related symptoms (SRSs), including lower urinary tract symptoms, pain, general health, work performance, sexual matter and additional problems. This study aims to evaluate the effectiveness between tamsulosin and solifenacin combined with tamsulosin for SRSs.Methods: This double blind randomized controlled trial used 50 patients. Between September 2020 and February 2021, patients underwent double-J stenting after retrograde ureteroscopy were analyzed. All patients would be randomized in a 1:1 ratio in a 1:1 ratio to receive either tamsulosin 0,4 mg (Group A: 25 participants) or tamsulosin 0,4 mg & solifenacin 5 mg combination (group B: 25 participants).We used the Ureteral Symptoms Score Questionnaire (USSQ) as an outcome measure at 1s, 2nd, 3rd and 4th weeks after stent insertion. Results: Group A was found more in women, while in group B was more in men. The highest age in group A and group B was 50-60 years old (36% and 64%). The location of stenting in group A was found more in left (60%), while the group B in the right (52%). Both groups had more patients who were normal nutritional status (60%). There was an improvement in pain and work performance after treatment in both groups, meanwhile group B showed better improvement than group A at all weeks. in addition, there was an improvement in urinary symptoms and sexual matter in group B better than in group A at 2nd to 4th week. Furthermore, group B showed better improvement in general health and additional problem only at 4th week. Conclusions: Combination therapy with tamsulosin and solifenacin improved USSQ score more than the monotherapy group. This implied that combination therapy is optimal for improving SRSs.
KORELASI NILAI INTRAVESICAL PROSTATIC PROTRUSION DAN POST VOID RESIDUAL URINE MENGGUNAKAN PEMERIKSAAN ULTRASONOGRAFI TRANSABDOMINAL DENGAN SKOR INTERNATIONAL PROSTATE SYMPTOM PADA PASIEN PEMBESARAN PROSTAT JINAK Kiki Amelia Marlina; Nurlaily Idris; Nikmatia Latief; Andi Alfian Zainuddin; Syakri Syahrir; Mirna Muis
E-Jurnal Medika Udayana Vol 10 No 9 (2021): Vol 10 No 09(2021): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2021.V10.i9.P16

Abstract

ABSTRAK Kiki Amelia M. Korelasi Nilai Intravesical Prostatic Protrusion dan Post Void Residual Urine Menggunakan Pemeriksaan Ultrasonografi Transabdominal dengan Skor International Prostate Symptom pada Pasien Pembesaran Prostat Jinak (Dibimbing oleh Nurlaily Idris dan Nikmatia Latief). Penelitian ini bertujuan untuk menganalisis korelasi nilai intravesical prostatic protrusion (IPP) dan volume post void residual (PVR) urine menggunakan pemeriksaan ultrasonografi transabdominal dengan skor international prostate symptom (IPSS) pada pasien pembesaran prostat jinak. Penelitian ini dilaksanakan di Departemen Radiologi RSUP dr. Wahidin Sudirohusodo Makassar, mulai Maret hingga Oktober 2020. Jumlah sampel sebanyak 48 pasien. Metode yang digunakan adalah uji korelasi Spearman’s rho dan Chi-square. Hasil penelitian menunjukkan adanya korelasi antara volume prostat (p=0,0001, r=0,736) dengan skor international prostate symptom (IPSS), semakin besar volume prostat maka semakin tinggi skor IPSS. Terdapat korelasi antara derajat intravesical prostatic protrusion (IPP) (p=0,0001, r=0,675) dengan skor international prostate symptom (IPSS), semakin tinggi derajat IPP maka semakin tinggi pula skor IPSS. Tidak terdapat korelasi antara post void residu (PVR) urine (p=0,076, r=0,258) dengan skor international prostate symptom (IPSS), besarnya volume PVR tidak berkorelasi dengan skor IPSS. Tidak terdapat korelasi antara kalsifikasi prostat (p=0,493) dengan skor international prostate symptom (IPSS), dimana keberadaan kalsifikasi prostat tidak berkorelasi dengan skor IPSS. Kata kunci: Pembesaran prostat jinak, ultrasonografi transabdominal, intravesical prostatic protrusion, post void residual urine, kalsifikasi prostat, skor international prostate symptom
Co-Authors Andi Alfian Zainuddin Berry Erida Hasbi Firdaus Kasim Khoirul Kholis Kiki Amelia Marlina Latief, Nikmatia Mirna Muis Muhammad Asykar Palinrungi Nurlaily Idris Syarif Bakri