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All Journal Sari Pediatri JOURNAL LA MEDIHEALTICO AKSONA Asian Journal of Health Research Prominentia Medical Journal
Nugraheni, Pramita Anindya
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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The Effect of Enterobiasis Prevention Education on the Level of Knowledge of Students Putri, Fransisca Dian Nathania; Nugraheni, Pramita Anindya; Risma, Risma
Journal La Medihealtico Vol. 5 No. 1 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i1.1041

Abstract

Enterobiasis is a disease caused by the parasitic worm Enterobius vermicularis. This disease often occurs in children aged 5-14 years. Enterobiasis is a disease that can cause symptoms, one of which is itching in the perianal area. This can cause sleep disorders so that a child's concentration can be disturbed and of course this will affect the child's learning ability, as well as impacting the quality of a generation. This study aims to determine the effect of health education on the level of knowledge of elementary school students in grades 4-6 at SDN Kaliasin 1 Surabaya regarding the prevention of enterobiasis. This research is an observational analytical study with a cross sectional design and uses primary data in the form of a questionnaire. The method used in this research is a quantitative method. The research results showed that before health education, respondents with a good level of knowledge were 24.7%, 48.1% were adequate, and 27.2% were poor, whereas after health education the results obtained were respondents with a good level of knowledge of 64.2%, 24.7% sufficient, and less by 11.1%. Based on the results of the paired Wilcoxon test, the p value was 0.000, which means the p value <0.005, so it can be concluded that there is an influence of health education on the level of knowledge of elementary school students in grades 4-6 at SDN Kaliasin 1 Surabaya on the prevention of enterobiasis.
Diagnostic and Treatment Challenges of Recurrent Tuberculosis in Patient with Drug-Induced Hepatotoxicity: A Case Report Devanda, Kasilda Pasha; Avelline, Kendraadine Dheayu; Lauwis, Keziah Queency; Kharizmatika; Hayati, Khofifah Bela Rachmanu; Adiwinoto, Ronald Pratama; Nugraheni, Pramita Anindya; Rasyida, Annisa Ullya
Asian Journal of Health Research Vol. 3 No. 3 (2024): Volume 3 No 3 (December) 2024
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v3i3.195

Abstract

Introduction: Pulmonary tuberculosis (TB) remains one of the most significant global health challenges, especially complicated by cases with incomplete treatment histories. The recurrence of TB poses diagnostic and therapeutic dilemmas that significantly impact patient outcomes. Case Presentation: We report a case of a 57-year-old female patient presenting with recurrent pulmonary TB after an incomplete treatment course. The patient's history revealed gaps in adherence to the prescribed TB regimen, leading to multiple relapses. In this study, we found that patients undergoing TB treatment may experience liver damage as a result of the TB medication, also known as DIH. Comprehensive diagnostic procedures, including chest radiography, sputum culture, and molecular testing, confirmed recurrent TB. The patient's clinical manifestations, treatment plan, and response to therapy are detailed. Conclusion: Recurrent TB is common, particularly in older adults, and is influenced more by environmental factors than occupation. Additionally, ATT poses risks of hepatotoxicity, especially in malnourished patients, underscoring the importance of managing side effects and addressing factors like malnutrition to prevent complications and improve outcomes. This case underscores the importance of complete adherence to TB treatment regimens and highlights the challenges in managing recurrent TB. It emphasizes the need for robust follow-up, patient education strategies, early diagnosis, and prompt intervention to prevent recurrence and enhance patient outcomes.
Laporan Kasus Serial : Anensefali Herdiyantini, Mita; Nugraheni, Pramita Anindya; Novitania, Milleniawati Putri; Renagupita, Melani Sinastri; Setiabudi, Martin Panglipuringtyas; Hendrawan, Michelle; Widisaputro, Michael Deni
Bahasa Indonesia Vol 5 No 2 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i2.5053

Abstract

Preface : Anencephaly is one of the most common forms of neural tube defects and is the second most serious congenital abnormality after congenital heart defects. The overall prevalence of Anencephaly in the world is 5.1 per ten thousand births. Case report : The first patient aged 26 years came without complaints when an ultrasound in the second trimester revealed Anencephaly fetal abnormalities and the pregnancy was terminated with vaginal delivery. The second patient aged 28 years came without complaints when an ultrasound in the first trimester revealed Anencephaly fetal abnormalities and a vaginal delivery was carried out. Discussion : Anencephaly is an abnormality in fetal development characterized by the absence of skull bones accompanied by a lack of most or all of the fetal brain tissue. The main risk factors are lack of folic acid consumption which can occur due to drugs that inhibit folate absorption, the body's increased need for folic acid, and lack of food intake. Early detection requires ultrasound, AFP and acetylcholinesterase examination in the second trimester. The recommended prevention is the consumption of folic acid from preparation for pregnancy until the time of pregnancy.
Pengaruh Terapi Oksigen Hiperbarik terhadap Anak dengan Gangguan Spektrum Autisme Nugraheni, Pramita Anindya; Untari, Ni Komang Sri Dewi; Agustin, Renny; Oktavia, Reza Mardiana Ayu; Rantika, Rheina Hasna; Hadi, Rifqi Athaya Vinanta; Utami, Rina Mega
Sari Pediatri Vol 25, No 5 (2024)
Publisher : Badan Penerbit Ikatan Dokter Anak Indonesia (BP-IDAI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14238/sp25.5.2024.316-21

Abstract

Latar belakang. Gangguan Spektrum Autisme merupakan kelainan perkembangan saraf dengan ciri-ciri gangguan komunikasi sosial, interaksi sosial yang terbatas, dan pola perilaku yang berulang, sesuai dengan klasifikasi DSM V. Terapi yang umum digunakan adalah Applied Behaviour Analysis, tetapi Terapi Oksigen Hiperbarik menjadi fokus studi terkini yang melibatkan pemberian oksigen 100% pada tekanan atmosfer yang lebih tinggi, menjadi opsi non-invasif yang dapat menyediakan oksigen optimal untuk organ tubuh.Tujuan. Penelitian ini bertujuan mengevaluasi pengaruh TOHB pada anak ASD melalui Childhood Autism Rating Scale.Metode. Studi analitik dilakukan dengan desain pra-eksperimental one group pretest-posttest, melibatkan 15 pasien ASD dari Lakesla Drs. Med. R. Rijadi S.,Phys. Data dikumpulkan dari Januari hingga Agustus 2023.Hasil. Analisis data pre-test dan post-test menunjukkan signifikansi (p=0.001). Evaluasi aspek hubungan dengan orang lain (p=0.004), imitasi (p=0.011), respon emosional (p=0.001), penggunaan objek (p=0.008), adaptasi (p=0.007), respon mendengar (p=0.014), rasa, bau, sentuh (p=0.034), ketakutan atau gugup (p=0.009), komunikasi verbal (p=0.059 dan p=0.157), tingkat aktivitas (p=0.004), level dan konsistensi respon intelektual (p=0.025), serta kesan umum (p=0.025).Kesimpulan. Pemberian TOHB pada anak ASD dapat meningkatkan berbagai aspek fungsi sosial dan menurunkan tingkat aktivitas, rasa takut, serta gugup. Penelitian ini memberikan dasar untuk lebih memahami peran TOHB dalam manajemen ASD.
A Rare Pediatric Case of Dengue Hemorrhagic Fever with Encephalopathy and Suspected Subdural Hemorrhage Cempakasari, Aulia; Rahmawati, Tiara; Arifin, Alief Qobidh Al Bashor; Syahputri, Dewi; Hutami, Firdha Yekti; Prameswari, Renata; Nugraheni, Pramita Anindya; Adiwinoto, Ronald Pratama; Adnyana, I Made Dwi Mertha
Asian Journal of Health Research Vol. 4 No. 3 (2025): Volume 4 No 3 (December) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i3.262

Abstract

Introduction: Dengue Hemorrhagic Fever (DHF) is a severe arboviral infection that rarely leads to neurological complications. Dengue encephalopathy, often secondary to metabolic disturbances or shock, presents a significant diagnostic and management challenge in the pediatric population. Case Presentation: We report the case of a 4-year-3-month-old obese girl presenting with fever, gastrointestinal symptoms, and progressively decreasing consciousness (apathetic). Diagnosis of DHF was confirmed by a positive NS1 antigen test, severe thrombocytopenia (nadir 14,000/µL), and hemoconcentration with pleural effusion. Hepatic involvement was noted (SGOT 117.81 U/L). Neurological involvement was characterized by clinical encephalopathy, and a head CT scan revealed hyperdense lesions suspecting subdural hemorrhage (SDH). The patient required multidisciplinary management in the Intensive Care Unit (ICU) for supportive fluid therapy, inotropic support (Dobutamine), and platelet transfusion. The patient showed marked clinical improvement and was discharged on day nine. At a two-week post-discharge follow-up, she demonstrated full cognitive and motor recovery with no neurological sequelae Conclusion: This case highlights the critical need for clinical vigilance for rare, simultaneous neurological complications (encephalopathy and suspected SDH) in pediatric DHF. It underscores that early diagnosis and aggressive, multidisciplinary supportive care can lead to complete recovery even in severe presentations.
Clinical Improvement in Autism Spectrum Disorder Symptoms Following Hyperbaric Oxygen as Adjuvant Therapy in a 12-Year-Old Boy Untari, Ni Komang Sri Dewi; Nugraheni, Pramita Anindya; Agustin, Renny; Oktavia, Reza Mardiana Ayu; Rantika, Rheina Hasna; Hadi, Rifqi Athaya Vinanta; Utami, Rina Mega; Adiwinoto, Ronald Pratama
AKSONA Vol. 6 No. 1 (2026): JANUARY 2026
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v6i1.70643

Abstract

Highlight: The potential role of hyperbaric oxygen therapy (HBO) as an adjunctive treatment for autism spectrum disorder (ASD), demonstrating significant improvements in clinical symptoms. By exploring the plausible mechanisms of HBO, the manuscript underscores the importance of further research and clinical trials to validate its efficacy and safety in the ASD population. This study adds to the literature advocating for innovative therapeutic strategies that address the complex interplay of oxidative stress, neuroinflammation, and mitochondrial dysfunction, inviting a personalized treatment approach.   ABSTRACT Introduction:  Autism spectrum disorder (ASD) is a multifaceted neurodevelopmental condition influenced by both genetic predispositions and environmental factors. Its underlying pathophysiology commonly involves oxidative stress, impaired cerebral perfusion, neuroinflammation, immune dysregulation, and mitochondrial dysfunction. Although conventional interventions, such as applied behavior analysis (ABA), are commonly employed, they may yield limited progress for some individuals. Consequently, emerging interventions, such as hyperbaric oxygen therapy (HBO), show promise for enhancing neurological outcomes and warrant further exploration. HBO, a well-established treatment for decompression sickness, is currently being investigated for its potential benefits in various neurological disorders, including ASD. Case: We present a case of ASD in a 12-year-old boy characterized by minimal eye contact, limited expressive language, and restricted, repetitive behaviors. On neurological examination, the patient was alert and capable of spontaneous eye opening, vocalizing incomprehensible words, and, at times, responding to simple commands. Despite undergoing ABA therapy, the patient exhibited limited developmental progress. The patient was subsequently undergoing hyperbaric oxygen therapy (HBO) at 1.3 ATA for 60 minutes for 10 days. Following the completion of HBO therapy, there was a decline in the CARS score from 41.5 (severe) to 29 (mild), the ATEC score from 115 to 68, the platelet count (51,000 / μL), and interleukin-1β levels (181.4 pg/mL). Conclusion: This case highlights the potential of HBO therapy as an adjunctive treatment modality for ASD, offering significant symptomatic improvements in a patient for whom traditional therapies were insufficient. The presumed mechanisms underlying these effects include anti-inflammatory effects and enhanced cerebral oxygen delivery, which may facilitate neuronal recovery and function. Given these findings, further research and clinical trials are warranted to confirm the therapeutic efficacy, long-term benefits, and safety profile of HBO therapy.
Co-Authors Adnyana , I Made Dwi Mertha Agustin, Renny Arifin, Alief Qobidh Al Bashor Avelline, Kendraadine Dheayu Cempakasari, Aulia Devanda, Kasilda Pasha Hadi, Rifqi Athaya Vinanta Hayati, Khofifah Bela Rachmanu Hendrawan, Michelle Herdiyantini, Mita Hutami, Firdha Yekti Kharizmatika Lauwis, Keziah Queency Miranda, Stefani Novitania, Milleniawati Putri Oktavia, Reza Mardiana Ayu Putri, Fransisca Dian Nathania Rahmawati, Tiara Rantika, Rheina Hasna Rasyida, Annisa Ullya Renagupita, Melani Sinastri Renata Prameswari Risma Risma, Risma Ronald Pratama Adiwinoto Setiabudi, Martin Panglipuringtyas Syahputri, Dewi UNTARI, NI KOMANG SRI DEWI Utami, Rina Mega Widisaputro, Michael Deni