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Comparison of serum soluble edoglin (sEng) level in eary onset preeclampsia, late onset preeclampsia and normal pregnant woman Aldika Akbar; Mita Herdiyantini; Aditiawarman Aditiawarman
Majalah Obstetri dan Ginekologi Vol. 25 No. 1 (2017): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.564 KB) | DOI: 10.20473/mog.V25I12017.10-15

Abstract

Objectives: This study aimed to compare the serum levels of soluble Endoglin (s-Eng) between early onset preeclampsia, late onset preeclampsia and normal pregnant women.Materials and Methods: This was an analytic observational study (Cross-Sectional) performed on 39 pregnant women with early-onset preeclampsia (EO-PE), late-onset preeclampsia (LO-PE), and normal pregnancy. The patients were consecutively chosen in Dr. Soetomo Hospital, Airlangga University Hospital and Dr. M. Soewandhi Hospital Surabaya in May-July 2016. The serum concentration of soluble Endoglin were collected by venous puncture taken from maternal circulation and measured by ELISA.Results: From this study, serum concentrations of soluble Endoglin was higher significantly on the early onset  preeclampsia compared with late onset preeclampsia and normal pregnancy (47,65 ± 40,17 vs 13,46 ± 9,48 vs 6,11 ± 1,45 ng/mL; p=0.000). Conclusion: This study shows angiogenic imbalance was more prominent compared in early-onset than late-onset preeclampsia. This may be because the placental dysfunction, placental ischemia, which produce excessive anti angiogenic factors, whic later causing endothelial dysfunction was more related to early onset preeclampsia.
Evaluasi Hasil Histerosalpingografi Pasien Infertil dengan Nyeri dan Laparoskopi di Rumkital Dr. Ramelan Surabaya Nanda Putra Prakasa; Mita Herdiyantini; Dody Taruna
HANG TUAH MEDICAL JOURNAL Vol 16 No 2 (2019): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRACT Background: Infertility can caused factors of cervix, uterine, tubal and peritoneal, ovulation and sperm factors in men. Abnormality of tubal factor and primary peritoneum factors are endometriosis and PID, which clinically give complain of pain. Checkup of tubal and peritoneum factors are difficult to conduct. It needs laparoscopic equipment and laparoscopic specialist doctors. Whereas the most convenient, cheapest, not invasive and large equipment which are used to find tubal factor is by checking-up Hysterosalpingography (HSG). HSG only can find tubal potential and peritoneal factor. Objective: to measure the relation between pain and checkup result of hysterosalpingography with laparoscopic examination results. Method: observational analytic which was retrospective longitudinal using secondary data and medical record infertile women who had been conducted HSG test before, which were conducted laparoscopy and registered in obstetrician at Rumkital dr. Ramelan Surabaya in Januari 2013 - December 2017 as population. The samples were 30 respondents. Furthermore, data analysis were calculated using Chi-square test, Fisher Exact Test. It was carried out the descriptive analysis for data by valuing Sensitivity, Specificity, Positive Predictive Value and Negative Divination Value. Result: data showed that there was relation between pain and the result of laparoscopy test in infertile patient and there was relation between the result of HSG test and the result of laparoscopy test in infertile paitients at Rumkital dr. Ramelan Surabaya. Conclusion: there is a relation between pain complain and the result of hysterosalpingography with laparoscopic examination results.
Karakteristik Partus Prematurus Imminens di Rspal Dr Ramelan Surabaya Periode Juni 2019 – Juni 2020 MALIKU NURROCHMAN WIDANDI; MITA HERDIYANTINI; KETUT EDY SUDIARTA
HANG TUAH MEDICAL JOURNAL Vol 19 No 2 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v19i2.141

Abstract

Background: The child mortality rate in the world and in Indonesia in particular is still high. Based on WHO data, Indonesia is in the top 10 countries with a total of 675,700 cases of premature birth. Premature labor is often preceded by signs of labor called Threatened Preterm Labor. Threatened Preterm Labor is the occurrence of a threat of labor in the form of uterine contractions and/or other signs of labor at gestational age between > 20 - < 37 weeks. If it does not get adequate treatment, it is often followed by premature birth. Prematurity increases the rate of cesarean delivery and increases child mortality. This study aims to determine the characteristics of pregnant women with Threatened Preterm Labor at RSPAL Dr. Ramelan Surabaya. Methods: This research is a descriptive study using purposive sampling technique. The research sample used Threatened Preterm Labor cases recorded in the medical records of RSPAL Dr. Ramelan Surabaya. Results: The results showed that 50 cases of Threatened Preterm Labor. Most of them occurred at the age of 20 - 35 years as many as 39 (78%), with a high school education level of 31 (62%), as many as 26 patients (52%) worked. Based on parity, most occurred in primiparous as many as 19 cases (38%). Based on ANC visits, the majority of patients who did not perform ANC were 43 patients (86%). Most of them had normal blood pressure as many as 37 patients (74%), 30 patients (60%) had low hemoglobin levels / anemia, and 29 patients (58%) had normal leukocyte levels. Most previous pregnancy history in normal pregnancy was 28 cases (56%). A total of 31 patients (62%) had complications in pregnancy. The success of tocolytic therapy was 34 cases (68%). Conclusion: Eighty-six percent of PPI patients admitted to RSPAL never had ANC, 60% of the samples were included in the anemia category, and 62% were motivated by complications of this pregnancy including premature rupture of membranes (PROM), preeclampsia, gemelli, gestational diabetes, infection, anemia, and polyhydramnios. Suggestion: more intensive public health education is needed, especially for pregnant women.
KEJADIAN DEPRESI PADA IBU POST PARTUM GEMELI DI RSUD Dr. SOEROTO NGAWI Mita Herdiyantini; Wienta Diarsvitri
Surabaya Biomedical Journal Vol 1 No 2 (2022): Januari
Publisher : Fakultas Kedokteran, Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/sbj.v1i2.20

Abstract

Tujuan Penelitian: Perubahan biologis selama kehamilan dapat menjadi penctus terjadinya gangguan psikologis mulai dari yang ringan hingga gangguan jiwa. Penelitian ini memberikan gambaran kejadian depresi pada ibu post partum yang melahirkan bayi kembar (gemeli) di RSUDD Dr. Soeroto Ngawi selama bulan Januari 2016-Maret 2016. Metode : Penelitian deskriptif ini menggunakan kuesioner Edinburgh Postnatal Depresion Scale (EPDS) pada 12 ibu post partum yang melahirkan gemeli di Ruang Nifas Wijaya Kusuma dan kontrol nifas di Poli Hamil/Kandungan Rumah Sakit Umum Dr. Soeroto, Ngawi selama bulan Januari 2016-Maret 2016. Hasil : Sebagian besar responden (75%) berpendidikan SD-SMP, 67% responden berusia 20-24 tahun, 67% responden tidak bekerja, 58% tidak pernah kontrol rutin selama kehamilan. Enam responden (50%) menyatakan jarang mengalami gangguan tidur, 33% menyatakan bahwa hampir setiap waktu mengalami gangguan tidur karena kecemasan yang dialami, 17% tidak pernah mengalami gangguan tidur. Mayoritas responden (58%) tidak pernah mengalami kejadian/peristiwa berat pada satu tahun sebelum hamil. Berdasarkan hasil Kuesioner EPDS didapatkan 58% responden kemungkinan tidak mengalami depresi, 25% responden kemungkinannya sedang untuk mengalami depresi, 17% responden kemungkinannya tinggi untuk mengalami depresi. Kesimpulan : Sebagian besar responden post partum gemeli yang kemungkinan mengalami depresi berasal dari kelompok usia 20-24 tahun, mempunyai anak lebih dari tiga, dan tidak rutin kontrol di poli RSUDD Dr. Soeroto Ngawi. Oleh karena itu diperlukan kerjasama lintas sektor untuk mencegah terjadinya depresi pada ibu post partum gemelli.
Effect of Submaximal Exercise on Trained and Untrained Intensity on Estrogen Levels in Female White Rats (Rattus Norvegicus) Wistar Strains Cinthya Fitri Paramitha; Mita Herdiyantini; Eric Mayo Dagradi; Annisa Ulya Rasyida
Jurnal Ilmiah Kedokteran Wijaya Kusuma Vol 13, No 1 (2024): March 2024
Publisher : Universitas Wijaya Kusuma Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30742/jikw.v13i1.2893

Abstract

Background: Trained and continuous physical activity can increase estrogen levels in women, while irregular activity can increase excessive Estrogen levels. Submaximal exercise is a recommended exercise to improve a woman's physiological function The purpose of this experiment was to determine the effect of submaximal exercise on trained and untrained intensity on Estrogen levels in female white rats (Rattus norvegicus) Wistar strains. Methods: This research was an experimental study using a post-test-only control group design using 30 female Wistar rats which were divided into 5 groups: control group not treated (K1), experimental group of animals with exercise intensity without intervention (K2), group of experimental animals with untrained intensity without intervention (K3), group of experimental animals with exercise intensity with intervention (K4), and experimental group of animals with exercise intensity with intervention (K4). experimental animals with untrained intensity treatment with intervention (K5). The intervention was swimming at moderate intensity with a duration of 85% of the maximum time to swim and a load of 8% of the rat's body weight. After the treatment period, all groups were terminated to take intracardiac blood measured using ELISA. Results: The data results were analyzed using statistical tests. The results of this study found that the trained group had lower Estrogen levels compared to the untrained group, but higher than the control group. The Kruskal-Wallis test show a significance value (p = 0.157), p> 0.05. Conclusion: In this study, there was no effect of submaximal exercise between trained and untrained intensity on Estrogen levels in Wistar strain female white rat.
Prevalensi Terjadinya Komplikasi pada Ibu Hamil dengan Infeksi Covid-19 Post Sectio Caesarea Utami, Nadila Rizqi; Herdiyantini, Mita; Budiarti, Retno; Harnanik, Titut
Jurnal Kesehatan Vol 13 No 1 (2024): Jurnal Kesehatan
Publisher : STIKES Ngesti Waluyo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46815/jk.v13i1.187

Abstract

Pregnancy is a period of fetal growth and development accompanied by physiological and immunological changes in the mother, making her more susceptible to infections, including COVID-19. Pregnancy accompanied by COVID-19 infection increases the risk of complications for pregnant women. This study aims to determine the prevalence of post-Caesarean section complications in pregnant women with COVID-19. The sampling method employed purposive sampling by observing medical record data at Dr. Ramelan Surabaya Hospital during the period from March 2020 to March 2023. Out of a total of 100 samples, there were 58 confirmed cases of COVID-19, with 8 cases (32.0%) of cardiovascular complications, consisting of 6 cases (75.0%) of PPH complications, and 2 cases (25.0%) of surgical wound infection complications. The prevalence of respiratory system complications included 13 cases (52.0%), with 9 cases (69.2%) of pneumonia complications and 4 cases (30.8%) of Acute Respiratory Distress Syndrome complications. One case (4.0%) of sepsis and 3 cases (12.0%) of maternal death complications were identified. The results of the data analysis using the Contingency Coefficient test showed a p-value of 0.001 (p < α), indicating a significant relationship between COVID-19 infection and an increased prevalence of complications in pregnant women. In conclusion, the study found 25 cases (43.1%) of post-Caesarean section complications in pregnant women with COVID-19, indicating an increased prevalence of complications in pregnant women with COVID-19 post-Caesarean section.
Stres dan Gangguan Siklus Menstruasi Mahasiswi Fakultas Kedokteran dan Psikologi Distyvanya, Shakira Azzahra; Nawangsasi, Peppy; Herdiyantini, Mita; Adiwinoto, Ronald Pratama; Setyawan, Febri Endra Budi
CoMPHI Journal: Community Medicine and Public Health of Indonesia Journal Vol. 4 No. 3 (2024): Februari
Publisher : Perhimpunan Dokter Kedokteran Komunitas dan Kesehatan Masyarakat Indonesia (PDK3MI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37148/comphijournal.v4i3.203

Abstract

ABSTRAK Stres merujuk pada kondisi karena adanya ketidaksesuaian antara harapan dan keinginan, di mana tuntutan dan kapabilitas seseorang untuk memenuhinya tidak sejalan. Diketahui bahwa prevalensi stres pada mahasiswi kedokteran cenderung tinggi karena tekanan yang mereka hadapi, sehingga menimbulkan disparitas dalam tingkat stres antara mahasiswi fakultas kedokteran dan psikologi. Penelitian ini bertujuan untuk mengetahui hubungan antara stres dengan gangguan siklus menstruasi pada mahasiswi Fakultas Kedokteran dan Fakultas Psikologi Universitas Hang Tuah. Metode penelitian menggunakan pendekatan cross-sectional dengan teknik simple random sampling. Penelitian melibatkan 92 mahasiswi Fakultas Kedokteran dan 59 mahasiswi Fakultas Psikologi Universitas Hang Tuah.. Hasil analisis statistik menggunakan uji Spearman, uji Tabulasi Silang, dan uji Kendall's tau-b menunjukkan adanya hubungan yang signifikan antara stres dengan gangguan siklus menstruasi (uji Spearman dan uji Tabulasi Silang: p = 0 dan tingkat signifikansi α = 0,05) dengan nilai koefisien korelasi sebesar 0,412. Temuan ini tidak mengindikasikan adanya hubungan signifikan antara stres dengan fakultas (uji Kendall's tau-b: p = 0,342 dan α = 0,05). Selain itu, tidak terdapat hubungan yang signifikan antara gangguan siklus menstruasi dan fakultas (uji Kendall's tau-b: p = 0,440 dan α = 0,05). Kata kunci: Stres; Gangguan Siklus Menstruasi;, Mahasiswi Kedokteran; Mahasiswi Psikologi
Laporan Kasus Serial : Anensefali Herdiyantini, Mita; Nugraheni, Pramita Anindya; Novitania, Milleniawati Putri; Renagupita, Melani Sinastri; Setiabudi, Martin Panglipuringtyas; Hendrawan, Michelle; Widisaputro, Michael Deni
Bahasa Indonesia Vol 5 No 2 (2024): Prominentia Medical Journal
Publisher : Universitas Ciputra Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37715/pmj.v5i2.5053

Abstract

Preface : Anencephaly is one of the most common forms of neural tube defects and is the second most serious congenital abnormality after congenital heart defects. The overall prevalence of Anencephaly in the world is 5.1 per ten thousand births. Case report : The first patient aged 26 years came without complaints when an ultrasound in the second trimester revealed Anencephaly fetal abnormalities and the pregnancy was terminated with vaginal delivery. The second patient aged 28 years came without complaints when an ultrasound in the first trimester revealed Anencephaly fetal abnormalities and a vaginal delivery was carried out. Discussion : Anencephaly is an abnormality in fetal development characterized by the absence of skull bones accompanied by a lack of most or all of the fetal brain tissue. The main risk factors are lack of folic acid consumption which can occur due to drugs that inhibit folate absorption, the body's increased need for folic acid, and lack of food intake. Early detection requires ultrasound, AFP and acetylcholinesterase examination in the second trimester. The recommended prevention is the consumption of folic acid from preparation for pregnancy until the time of pregnancy.
Upaya peningkatan kesadaran ancaman kanker serviks melalui konseling skrining berbasis inspeksi visual asam asetat (IVA) Al Hasan, Hafidz Ramadhan; Adiwinoto, Ronald Pratama; Ariewibawa, Fariz Atiqi; Sianipar, Habel Ryan Annerico; Sudiarta, Ketut Edy; Herdiyantini, Mita
Jurnal Lentera Kesehatan Masyarakat Vol. 4 No. 2 (2025): Jurnal Lentera Kesehatan Masyarakat
Publisher : PT. Lentera Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69883/fgp8pp39

Abstract

Kanker serviks masih menjadi masalah kesehatan masyarakat yang signifikan, terutama di negara berpenghasilan rendah dan menengah, sehingga upaya skrining (deteksi dini) risiko kanker serviks, salah satunya berupa IVA(Inspeksi Visual Asam asetat) penting untuk upaya. Penelitian ini bertujuan mengevaluasi dampak intervensi konseling berbasis Model Keyakinan Kesehatan (Health Belief Model) dalam meningkatkan pengetahuan dan kemauan guru serta staf sekolah untuk menjalani skrining kanker serviks dengan metode Inspeksi Visual Asam Asetat (IVA). Intervensi berupa sesi konseling dilaksanakan di delapan sekolah, dan pengetahuan serta sikap peserta diukur sebelum dan sesudah edukasi. Data hasil penelitian disajikan dalam bentuk tabel, diagram dan dianalisis dengan uji statistik paired-student's T test. Hasil menunjukkan adanya peningkatan skor pengetahuan yang signifikan secara statistik, dari 65,2 ± 12,4 menjadi 84,7 ± 9,8 (p < 0,001). Persentase peserta yang menyatakan kesediaan untuk menjalani skrining IVA juga meningkat dari 58,3% menjadi 87,5% (p = 0,003). Namun demikian, cakupan skrining aktual hanya naik dari 12% menjadi 14% (p = 0,08), masih jauh dari target partisipasi sebesar 70%. Kesimpulan penelitian ini adalah diperlukan strategi komprehensif yang tidak hanya fokus pada peningkatan pengetahuan, tetapi juga mengatasi hambatan psikologis, budaya, dan akses pelayanan. Pendekatan multifaset yang melibatkan edukasi berkelanjutan, dukungan sosial, peran aktif tenaga kesehatan masyarakat, serta peningkatan aksesibilitas layanan skrining diyakini dapat mendorong partisipasi lebih luas. Kesimpulannya, intervensi konseling dapat meningkatkan kesadaran dan kemauan, namun dampaknya terhadap cakupan skrining masih terbatas sehingga perlu didukung langkah strategis yang lebih menyeluruh.
Cognitive Resilience Amongst the Elderly in Socah Village's Fishing and Non-Fishing Communities Adiwinoto, Ronald Pratama; Putri, Ida Ayu Govinda Lazenobia De Sanjaya; Wendra, Sadya; Liliawanti, Liliawanti; Herdiyantini, Mita; Putra, Oki Nugraha; Adnyana, I Made Dwi Mertha
Indonesian Journal of Global Health Research Vol 6 No 3 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i3.3122

Abstract

Alzheimer's Indonesia (ALZI) reports a significant and growing prevalence of Orang Dengan Demensia Dementia (ODD), which is projected to reach 2 to 4 million individuals by 2050. Dementia is often attributed to cognitive deficits, prompting this study to investigate and compare the Community Mini Mental State Examination (MMSE) scores among elderly professionals, specifically fishermen and non-fishermen, residing in Socah Village, Bangkalan, East Java. Objective: This research aims to elucidate the extent of cognitive impairment in this demographic. Method: An analytical observational study employed a purposive sampling approach, with a total sample size of 96 individuals. The age categories ranged from 45 to 89 years, adhering to the Badan Pusat Statistik 2015 guidelines. Data collection took place during August to September 2022. Results: The results of the Mann-Whitney's test indicate a significant difference in Mini Mental State Examination (MMSE) scores between elderly fishermen and non-fishermen in Socah Village, with a p-value of 0.001 (p < α, α = 0.05). Conclusion: This finding leads to the conclusion that there is a notable disparity in MMSE scores among elderly professionals, highlighting the substantial impact of physical activity on cognitive function.