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All Journal Jurnal Mahasiswa Farmasi Fakultas Kedokteran dan Ilmu Kesehatan UNTAN Journal Pharmacy of Tanjungpura
Deisberanda, Fortunata Saesarria
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Health Professions Medicine & Pharmacology

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ANALISIS KADAR ASAM LEMAK BEBAS DAN PENETAPAN BILANGAN ASAM MINYAK CINCALOK Deisberanda, Fortunata Saesarria; Nurbaeti, Siti Nani; Kurniawan, Hadi
Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN Vol 4, No 1 (2019): Jurnal Farmasi Kalbar
Publisher : Jurnal Mahasiswa Farmasi Fakultas Kedokteran UNTAN

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Abstract

Cincalok merupakan udang fermentasi khas Kalimantan Barat yang memiliki banyak kandungan bermanfaat seperti astaxanthin, omega-3, dan omega-6. Cincalok yang diekstraksi menggunakan minyak VCO telah diuji keamanannya dan memiliki nilai LD50>5000 mg/kgBB (praktis tidak toksik) sehingga berpotensi dikembangkan sebagai suplemen. Penelitian ini bertujuan untuk menguji kualitas minyak cincalok melalui penentuan kadar asam lemak bebas dan bilangan asam. Analisis mutu minyak diperlukan agar menjamin hasil produk minyak cincalok berkualitas, berkhasiat, dan tahan lama. Pengujian dilakukan menggunakan metode titrasi alkalimetri secara triplo. Hasil yang diperoleh yaitu kadar asam lemak bebas berturut-turut 1,031%; 0,807%; 1,031% dan bilangan asam berturut-turut 0,002; 0,002; 0,002. Menurut standar yang ditetapkan oleh IFOMA (International Fishmeal and Oil Manufacturers' Association) kandungan asam lemak bebas minyak hewani yang baik yaitu sebesar 1-7%, sehingga minyak cincalok tergolong baik.
REVIEW: INOVASI TEKNOLOGI FARMASI DALAM MENINGKATKAN KEPATUHAN PENGOBATAN PADA PASIEN PEDIATRIK DAN GERIATRIK Deisberanda, Fortunata Saesarria; Rommy, Rommy
Journal Pharmacy Of Tanjungpura Vol. 3 No. 1 (2025): Oktober
Publisher : Universitas Tanjungpura

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This article reviews innovations in pharmaceutical technologies aimed at improving medication adherence in pediatric and geriatric patients, with a focus on innovative formulations. The purpose of this review was to assess the effectiveness of novel formulations in enhancing therapeutic outcomes and patient adherence, as well as to identify challenges in their clinical implementation. The findings from various studies indicate that technologies such as 3D printing, orally disintegrating tablets (ODTs), and chewable tablets improve therapeutic results and patient compliance by offering flexibility in dose adjustments and drug delivery. Additionally, formulations tailored to patient preferences, such as gummies and orally disintegrating films, have proven effective in enhancing medication acceptance, especially in pediatric and geriatric populations. While these technologies show great potential, challenges related to regulation and manufacturing barriers, such as quality standardization and production scalability, remain major obstacles. Therefore, further and more comprehensive research is required to ensure the widespread implementation of these technologies in pediatric and geriatric patient care.
PENDEKATAN NANOTEKNOLOGI DALAM PENGEMBANGAN IMUNOMODULATOR DARI FLORA ENDEMIK KALIMANTAN: SCOPING REVIEW Deisberanda, Fortunata Saesarria
Journal Pharmacy Of Tanjungpura Vol. 3 No. 2 (2026)
Publisher : Universitas Tanjungpura

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Indonesia possesses high biodiversity with significant potential as a source of natural immunomodulators, particularly from endemic flora of Kalimantan such as Eurycoma longifolia, Stenochlaena palustris, and Piper crocatum, which are rich in bioactive secondary metabolites. However, their clinical application remains limited due to poor bioavailability and physicochemical instability. This scoping review was conducted following the methodology of the Joanna Briggs Institute using the Population, Concept, Context (PCC) framework. Literature searches were systematically performed in PubMed, Scopus, Web of Science, and ScienceDirect, followed by descriptive analysis to map formulation strategies, immunomodulatory mechanisms, and translational challenges. The findings indicate that pharmaceutical nanotechnology, including nanoemulsions, self-nanoemulsifying drug delivery systems (SNEDDS), and nanoparticles, significantly enhances solubility, stability, and delivery efficiency of bioactive compounds. At the cellular and molecular levels, immunomodulatory effects involve enhanced phagocytic activity, regulation of cytokines such as TNF-α, IL-6, and IL-10, and modulation of signaling pathways including NF-κB and MAPK. Nevertheless, clinical translation remains challenged by safety concerns, formulation stability, high development costs, and regulatory requirements. Overall, pharmaceutical nanotechnology offers a promising approach to optimize natural product-based immunomodulators; however, further standardization, robust clinical evidence, and multidisciplinary collaboration are essential to support successful clinical implementation.
Co-Authors Hadi Kurniawan Rommy, Rommy Siti Nani Nurbaeti