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All Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Majalah Biomorfologi (Biomorphology Journal) Jurnal Psikiatri Surabaya (Surabaya Psychiatry Journal) GEMBIRA (Pengabdian Kepada Masyarakat) Folia Medica Indonesiana
Qorib, Mohammad Fathul
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Religion Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Public Health Social Sciences

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Mental Health Status and Literacy of Adolescent in Rural Area of Mojokerto, East Java, Indonesia Ardana, Arin Aurilia; d'Arqom, Annette; Puteri, Fira Adilah; Indiastuti, Danti Nur; Nasution, Mhd Zamal; Hasanatuludhhiyah, Nurina; Qorib, Mohammad Fathul; Setiawati, Yuani; Junaidah Yusof
Jurnal Psikiatri Surabaya Vol. 14 No. 2 (2025): November
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jps.v14i2.64237

Abstract

Introduction: Adolescence is a crucial period for the development of mental health. Enhancing mental health literacy can reduce stigma and support early intervention and treatment. This study aims to examine the mental health status and mental health literacy among middle and late adolescents in a rural area of Mojokerto District, East Java, Indonesia. Methods: A total of 81 high school students from Mojokerto District participated in the study. The Depression Anxiety Stress Scale – Youth version (DASS-Y) was used to assess symptoms of depression, anxiety, and stress. Mental health literacy was measured using the Adolescent Mental Health Literacy Questionnaire (AMHL). The validity of the AMHL was tested on 30 students using Pearson correlation. Descriptive statistics were used to analyze the prevalence of mental health conditions and levels of mental health literacy. Inferential statistics were applied to explore associations between mental health status, literacy, and sociodemographic variables. Results: The results showed that 53% of students experienced symptoms of mental health problems. While most students demonstrated moderate to satisfactory mental health literacy, significant gaps remain. Enhancing literacy may help reduce stigma and improve knowledge and attitudes toward mental health. Sociodemographic factors and mental health literacy showed limited influence on mental health status. However, sex was significantly associated with both mental health literacy and mental health status (p = 0.016 and p = 0.032, respectively). Conclusion: Mental health during adolescence significantly influences adult well-being. Improving adolescent mental health literacy is crucial for early recognition, stigma reduction, and better access to mental health care.
Selection of Medical Therapy in Glaucoma Patients in the Outpatient Eye Clinic Soetomo General Academic Hospital Surabaya Praba, Venansya Maulina; Primitasari, Yulia; Qorib, Mohammad Fathul; Loebis, Rozalina
Folia Medica Indonesiana Vol. 57, No. 4
Publisher : Folia Medica Indonesiana

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Highlight: • Medical therapy selection in the outpatient eye clinic were determined. • Treatment of prostaglandin analogue therapyfor primary open angle glaucoma was the most common glaucoma type. Abstract: Glaucoma is the second leading cause of blindness and the third cause of visual impairment. Glaucoma management includes medical therapy, laser, and incisions. This study aims to determine the selection of medical therapy in the outpatient eye clinic Soetomo General Academic Hospital Surabaya. This study was a retrospective descriptive study. The variables were type of glaucoma, visual acuity, intraocular pressure, and drug therapy. Data processing was done by collecting, grouping, and describing data. Glaucoma was mostly common in 50-64 years old (37.66%), male (50.65%), most patients lived in Surabaya (53.68%), the most common type was Primary Open-Angle Glaucoma (32.90%), the most medical therapy given in the first visit in 2019 was single medical therapy (67.97%), the most single drug therapy was latanoprost (49.68%), the most drugs combination was timolol maleat with acetazolamide (35.14%), the most commonly drugs class were prostaglandin analogues (48.48%), most of the visual acuity values were 6/6 - 6/18 (1,00 – 0,33) (37.88%), most intraocular pressure was in the 11-21 mmHg (62.55%). The most common type of glaucoma was primary open angle glaucoma with the most therapy given was prostaglandin analogue.
DAMPIT ROBUSTA COFFEE EFFECT ON THE CREATININE KINASE LEVELS AND MUSCLE PAIN SCALES AMONG SPORT ENTHUSIAST Salamy, M. Fath Alhaqqi Sanis; Qorib, Mohammad Fathul; Herawati, Lilik; Darmawan, Rizky; Mujahiddin, M. Izzul; Salamun, Salamun; Salamy, Ahmed Zaiyan Nahel; Salamy, Achmad Yarziq Mubarak Salis; Mohamed, Moh Nahar Azmi; Ramadhan, Ain Darojah Siddiq Ramadhan
Folia Medica Indonesiana Vol. 61, No. 2
Publisher : Folia Medica Indonesiana

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Abstract

Excessive eccentric exercise often results in muscle injury, reflected by elevated serum creatine kinase (CK) levels and delayed onset muscle soreness (DOMS). In Indonesia, coffee consumption after exercise has increased, with Dampit Robusta Coffee (DRC)—a local variety rich in caffeine and antioxidants considered a potential aid for recovery. This study evaluated the effect of DRC consumption on biomarkers of muscle damage and perceived soreness. A single-blind randomized controlled trial was conducted on 20 healthy untrained men aged 20–25 years, allocated into treatment (n = 10) and control (n = 10) groups. The treatment group consumed brewed DRC (≈200 mg caffeine/day) for five consecutive days, while the control group received placebo (coffee-flavored water). All participants performed a modified YMCA step test as an eccentric exercise protocol. Serum CK levels were measured at 2 and 24 hours post-exercise, and muscle soreness was assessed using a visual analogue scale (VAS). At both 2 and 24 hours, mean CK levels were lower in the DRC group compared with control, but differences were not significant (p > 0.05). However, analysis of CK change (ΔCK) showed a significant between-group difference, with CK decreasing in the DRC group but increasing in the control group (p = 0.031). VAS scores decreased significantly over time within both groups (p = 0.05), but between-group differences remained nonsignificant (p > 0.05). In conclusion, DRC consumption attenuated CK elevation after eccentric exercise, suggesting a protective effect against muscle injury, although its effect on soreness was inconclusive. Further studies with larger and more diverse samples are needed.
Effects of Minocycline as a Neuroprotective Agent for Stroke on Mmp-9 Levels, Functional Outcome, and Mortality Nisa, Ayu Imamatun; Damayanti, Arlia Ayu; Nagasastra, Jeffri; Machin, Abdulloh; Qorib, Mohammad Fathul; , Retnaningsih; Hamidi, Baarid Luqman
Folia Medica Indonesiana Vol. 60, No. 2
Publisher : Folia Medica Indonesiana

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Highlights: 1. As minocycline plays an important role in stroke microglia activation and iron chelation, it is important to further analyze its effects on stroke treatment. 2. This meta-analysis revealed a significant effect of minocycline therapy, as evidenced by improved functional outcomes and inhibited matrix metalloproteinase-9 (MMP-9) activity. Abstract Stroke is the most common and devastating cerebrovascular disease. Many neuroprotective medications, such as scale and minocycline, have been developed to help the nervous system recover or regenerate after a stroke. However, it remains unclear whether minocycline provides a beneficial effect on stroke. We conducted this systematic review and meta-analysis to synthesize the effects of minocycline in stroke treatment. The systematic review was registered in the International Prospective Register of Systematic Reviews (PROSPERO), with registration number CRD42023485168. The quality of the eligible studies was assessed using the Jadad scale. This systematic review included three ischemic stroke trials, seven intracerebral hemorrhage trials, and one study on acute stroke. There was a significant association between minocycline intervention and stroke severity according to the National Institute of Health Stroke Scale (NIHSS), with a pooled mean difference (MD) of -1.92, a 95% confidence interval (CI) of -3.39 to -0.45, and a value of p=0.01. In the subgroup of ischemic stroke, the modified Rankin Scale (mRS) was significantly lower in the minocycline treatment group compared to the control group (MD=-0.89, 95% CI=-1.54 to -0.25, p=0.007). Additionally, matrix metalloproteinase-9 (MMP-9) levels for the intracerebral hemorrhage subgroup were significantly lower in the minocycline treatment group compared to the control group (MD=-19.93, 95% CI=-36.9 to -2.96, p=0.02). The analysis revealed that minocycline intervention was not significantly associated with hematoma volume, mortality, or stroke recurrence. Our findings indicate that minocycline supplementation is a potential intervention strategy for treating ischemic stroke and intracerebral hemorrhage.
PENINGKATAN PENGETAHUAN TATA KELOLA NYERI SENDI PADA TENAGA KESEHATAN DASAR DI KECAMATAN JETIS KABUPATEN MOJOKERTO Kusuma Eko Purwantari; Prasetiowati , Lucky; Indiastuti , Danti Nur; Qorib, Mohammad Fathul
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 3 No 06 (2025): DESEMBER 2025
Publisher : Media Inovasi Pendidikan dan Publikasi

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Abstract

Nyeri sendi termasuk salah satu keluhan yang sering didapatkan pada lansia. Adanya anggapan yang salah di masyarakat bahwa keluhan nyeri sendi disebabkan oleh kelainan kadar asam urat dan kolesterol. Hal ini juga didukung kurang tepatnya diagnosa yang ditegakkan oleh tenaga kesehatan, selanjutnya berakibat penanganan yang salah. Tenaga kesehatan yang meliputi dokter umum, bidan desa dan perawat merupakan lini terdepan,sebagai tempat pilihan lansia untuk mendapatkan pelayanan kesehatan. Tujuan pengabdian masyarakat ini untuk meningkatkan pengetahuan tenaga kesehatan tentang nyeri sendi sehingga terwujud penatalaksanaan yang tepat. Selain itu tenaga kesehatan diharapkan  mampu menjadi jembatan untuk meluruskan pemahaman yang salah di masyarakat. Kegiatan berupa penyuluhan dan pelatihan yang dilanjutkan dengan diskusi. Materi yang disampaikan meliputi anatomi klinik nyeri sendi, pemeriksaan dasar sendi dan tata laksana nyeri sendi baik farmakologi dan non farmakologi. Evaluasi pelaksanaan kegiatan ini menggunakan metode pre test dan post test. Hasil dari pre test dan post test dilakukan uji paired t- test, dengan hasil signifikan apabila p > 0,05. Hasil yang diperoleh, terdapat peningkatan rerata nilai yaitu rerata pre test sebesar 1,15 ± 6,19 dan rerata post test sebesar  72,41 ± 37,87, dengan  nilai p = 0.000, menunjukkan beda signifikan. Hal ini menggambarkan adanya peningkatan pengetahuan peserta yang meliputi gejala, pemeriksaan dasar dan tata laksana nyeri sendi. Pengetahuan mengenai gejala klinis dan pemeriksaan dasar sendi diperlukan untuk menegakkan diagnosa. Diagnosa yang tepat sangat diperlukan agar penderita mendapat penanganan yang tepat.  
Profile of Analgesics in Toddler Patients Undergoing Surgery at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, January 2021-December 2021 Hernando, Devin; Maulydia, Maulydia; Qorib, Mohammad Fathul; Santoso, Kohar Hari
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): JANUARY 2026 (IN-PROGRESS ISSUE)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.8-14

Abstract

Highlights: Pain is the most common complaint in every medical procedure. Pain management in toddlers requires special attention due to the need to consider various factors.   Abstract Introduction: Pain is the most frequent complaint in all medical procedures. Managing procedures in toddlers requires special attention due to various influencing factors. The 19th century witnessed significant advancements in analgesics. Analgesics help manage pain that may arise from procedures performed on toddlers. Methods: This study identified the analgesic profile in toddlers undergoing surgery at the Integrated Surgery Center (GBPT) of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to December 2021. It was a retrospective descriptive study using medical records. The sample included toddlers who had surgery and received analgesics at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. The sampling technique used was total sampling. Results: During the period from January to December 2021, a total of 451 pediatric patients underwent surgery at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. A total of 232 patients were excluded due to incomplete medical records. A total of 219 patients met the criteria. The majority were 1-year-old (32.42%), with male patients being predominant (58.9%). Most toddlers had a normal body mass index (BMI). The majority of surgeries lasted 1-3 hours (64.38%). The most common procedures were debridement and wound dressing (11.87%). Opioids were the most frequently used analgesics (41%), with fentanyl being the most common (71.85%), while paracetamol was the primary non-opioid analgesic (43.33%). The most common pain intensity before and after surgery was no pain. Conclusion: Analgesics help manage pain from procedures in toddlers. Opioids were the most frequently used, with fentanyl being the most common.
The Potential of Ethanol Extract of Dutch Eggplant (Solanum betaceum) against caspase-3 Expression in the Kidneys of Mice (Mus musculus) Exposed to Lead Acetate Rifatus Solicha; Rahaju, Anny Setijo; Qorib, Mohammad Fathul; I’tishom, Reny; Arfian, Nur
Majalah Biomorfologi 2026: MAJALAH BIOMORFOLOGI (IN PRESS)
Publisher : Universitas Airlangga, Surabaya, Indonesia

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Abstract

Background: Lead (Pb) exposure remains an environmental health concern due to its toxicity, particularly to the kidneys, where it can cause nephrotoxicity. The accumulation of lead acetate induces oxidative stress through elevated reactive oxygen species (ROS) levels, which subsequently activate the apoptosis pathway characterized by increased caspase-3 expression. Caspase-3 serves as the primary executor enzyme in apoptosis and functions as a key indicator of kidney cell injury. Natural antioxidants, such as the ethanol extract of Dutch eggplant (Solanum betaceum), are rich in flavonoids and can protect kidney tissue by neutralizing free radicals and inhibiting apoptosis. Given these properties, Solanum betaceum has emerged as a candidate for protecting the kidneys against damage caused by heavy metals. Objective: This study investigated whether ethanol-extracted Dutch eggplant could protect the kidneys of mice (Mus musculus) exposed to lead acetate by looking at its effect on caspase-3 expression. The research also examined whether the extract’s protective effect depended on the dose given. Materials and Methods: This experimental research employed a post-test control group design. The authors classified the mice into five groups (K0, K1, P1, P2, and P3). The treatment groups received Dutch eggplant extract at varying doses administered concurrently with lead acetate exposure. Caspase-3 expression was evaluated using immunohistochemistry (IHC) and assessed using an H-score, followed by statistical analysis with SPSS. Results: Lead acetate increased caspase-3 expression compared to the negative control group (K1: 122.00 vs. K0: 71.00). Administration of Dutch eggplant extract reduced caspase-3 expression in a dose-dependent manner. Conclusion: The ethanol extract of Dutch eggplant has demonstrated potential nephroprotective effects against lead acetate-induced kidney damage by reducing caspase-3 expression.
Co-Authors , Retnaningsih Achmad Yarziq Mubarak Salis Salamy Annette d’Arqom, Annette Anny Setijo Rahaju, Anny Setijo Ardana, Arin Aurilia Damayanti, Arlia Ayu Hamidi, Baarid Luqman HERAWATI, LILIK Hernando, Devin Indiastuti , Danti Nur Indiastuti, Danti Nur I’tishom, Reny Junaidah Yusof Kusuma Eko Purwantari Machin, Abdulloh Maulydia, Maulydia Mhd Zamal Nasution Mohamed, Moh Nahar Azmi Mujahiddin, M. Izzul Nagasastra, Jeffri Nisa, Ayu Imamatun Nur Arfian, Nur Nurina Hasanatuludhhiyah Praba, Venansya Maulina Prasetiowati , Lucky Primitasari, Yulia Puteri, Fira Adilah Ramadhan, Ain Darojah Siddiq Ramadhan Rifatus Solicha Rizky Darmawan, Rizky Rozalina Loebis, Rozalina Salamun Salamun Salamy, Ahmed Zaiyan Nahel Salamy, M. Fath Alhaqqi Sanis Santoso, Kohar Hari Santoso Hari Yuani Setiawati