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All Journal JMM (Jurnal Masyarakat Mandiri) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Journal of Social Research Jurnal Kedokteran Hewan Jurnal Penyakit Dalam Indonesia
Murzalina, Cut
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Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences Veterinary Other

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Karakteristik Pasien Rinitis Alergi dengan Hasil Uji Cukit Kulit Positif yang Berobat di Poliklinik THT-KL Rumah Sakit Umum Daerah Zainoel Abidin Banda Aceh T.R, T. Husni; Murzalina, Cut; Elvia, Elvia; Alia, Dina; Razali, Rezania; Annisa, Siti Nur; Putra, Teuku Romi Imansyah; Farhana, Rika
Jurnal Penyakit Dalam Indonesia Vol. 11, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Introduction. Allergic rhinitis is an inflammatory disease mediated by IgE in the nasal mucosa, resulting from allergen sensitization and causing various clinical symptoms. The skin prick test is the primary diagnostic technique used to detect specific IgE antibodies against allergenic proteins and peptides. The incidence of allergic rhinitis in Indonesia ranges from approximately 1.5% to 12.4% and increases every year. This study aims to determine the characteristics of allergic rhinitis sufferers with positive skin prick test results who received treatment at the ENT outpatient service of Zainoel Abidin Regional General Hospital (RSUDZA) Banda Aceh from January 2019 to March 2020. Methods. This was a retrospective descriptive study with a cross-sectional design that utilized secondary data from patient medical records. The samples were collected using the total sampling technique, encompassing a total of 62 patients in this study. Results. This study revealed that allergic rhinitis sufferers with positive skin prick test results were predominantly in the age group 17-25 years (27.4%), female (69.4%), and from Banda Aceh (56.5%). Most of the rhinitis patients were students (41.9%), with the highest level of education being high school (43.5%). Allergic rhinitis is frequently caused by house dust mites (24.2%) as inhalant allergens and shrimp (26.3%) as ingested allergens. Most allergic rhinitis patients who visited complained most frequently of sneezing more than five times (26.3%). Conclusions. This study concluded that the characteristics of allergic rhinitis sufferers with positive skin prick test results in RSUDZA are predominantly in the late adolescent age group (17-25 years), female, with house dust mites and shrimp as the main allergens, and the most common clinical symptom is sneezing more than 5 times.
Analisis Nilai Anthropometri Dan Malnutrisi Pada Laki-Laki Dan Perempuan Usia 17-22 Tahun: Suatu Studi Cross-Sectional Yusni, Yusni; Yusuf, Hanifah; Murzalina, Cut; Rahman, Safrizal
Majalah Kedokteran Indonesia Vol 74 No 6 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.6-2024-928

Abstract

Introduction: Malnutrition is a worldwide problem that has yet to be resolved, and its prevalence in Indonesia has increased in tandem with changes in people’s lifestyles. Method: This study aims to determine nutritional status based on anthropometric values and investigate malnutrition in male and female aged 17–22 years. The research was conducted using a cross-sectional study. The subjects were male and female, aged 17–22 years, and healthy, with a total of 1,669 male (n=210) and female (n=1459). A questionnaire was used to obtain data. The data was analyzed using a chi-square test (p less than 0.05) and an independent sample t-test (p less than 0.05). Result: Malnutrition was found in subjects who were underweight (male=28.10% and female=26.39%), overweight (male=8.10% and female=9.32%), and obese (male=8.57% and female=6.85%). Total malnutrition in male and female was 27.25% underweight, 8.71% overweight, and 7.71% obese. Nutritional status was not related to gender (p greater than 0.05): underweight (p=0.74), normo-weight (p=0.48), overweight (p=0.34), and obesity (p=0.74). Conclusion: The double burden of malnutrition in males and females aged 17-22 years in Banda Aceh, Aceh, Indonesia is undernutrition and overnutrition, cases of undernutrition were more numerous than overweight and obesity, even though the number of malnutrition cases did not show any difference between men and women in all categories.
Sport Students' Hematology Profiles as Detected By The Automatic Sysmex XP-300 at Keberkatan Olahraga Senior High School In Aceh Munadi, Munadi; Desiana , Desiana; Murzalina, Cut
Journal of Social Research Vol. 4 No. 3 (2025): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v4i3.2462

Abstract

Physical activity has long been linked to modifications in hematologic profiles as the body's compensating response to the stress of physical training. Several earlier research studies have discovered that physical activity impacts red blood cells, leukocytes, and platelets, while the findings remain contentious. Monitoring an athlete's hematologic profile is critical for effective training management. The purpose of this study is to analyze the hematologic profile of young adults who attend sports-specialized schools. This cross-sectional study included 30 students (15 males and 15 females). Blood samples were collected using standard venipuncture methods and examined on an automatic Sysmex XP-300 analyzer. The analytical results revealed that all participants had mean or median values for each complete blood count (CBC) parameter and leukocyte differential count that were normal for the general population. Females showed greater mean/median values for all CBC indices except hemoglobin, hematocrit, erythrocytes, MCHC, and RDW. For ESR (erythrocyte sedimentation rate), all participants exhibited normal levels, with females having greater levels. The leukocyte differential count showed that the results for male and female patients were comparable. Sport students' hematologic profiles are normal for the overall community. However, it is critical to remember that physical activity alters the blood and its components, prompting the need for hematologic indices specific to athletes or sports students.
MENJAGA KESEHATAN DAN KEBUGARAN KARDIORESPIRASI MELALUI PEMERIKSAAN KOMPREHENSIF SEBAGAI UPAYA PREVENTIF HIPERTENSI Yusni, Yusni; Idayati, Ratna; Zakiaturrahmi, Zakiaturrahmi; Murzalina, Cut; Nugraha, Gartika Setiya; Shidqi, Muhammad
JMM (Jurnal Masyarakat Mandiri) Vol 9, No 2 (2025): April
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jmm.v9i2.29565

Abstract

Abstrak: Pemeriksaan kebugaran jantung paru (kardiorespirasi) merupakan suatu upaya meningkatkan kesehatan dan deteksi dini terhadap penyakit jantung termasuk hipertensi pada masyarakat. Mengingat hipertensi merupakan penyakit lifetime risk dan silent killer sehingga kegiatan deteksi dini ini penting untuk menurunkan risiko kematian akibat komplikasi. Kegiatan Pengabdian Kepada Masyarakat (PKM) ini bertujuan untuk melakukan pemeriksaan kesehatan dan tingkat kebugaran kardiorespiratori pada masyarakat khususnya kelompok usia muda. Kegiatan ini dilakukan dengan metode pemeriksaan kesehatan (anamnesis, pemeriksaan denyut nadi istirahat, dan tekanan darah (TD)) dan pemeriksaan kebugaran kardiorespirasi dengan mengukur nilai Volume Oksigen Maksimum (VO2 maks). Mitra pada kegiatan PKM ini adalah kelompok anak muda laki-laki (usia 19-22 tahun) yang berjumlah sebanyak 12 orang, Banda Aceh. Evaluasi hasil pemeriksaan tekanan darah adalah normal jika nilai sistolik <120 mmHg dan diastolik <80 mmHg. Hasil kegiatan PKM ini menunjukkan bahwa total sebanyak 12 orang memiliki tekanan darah dan denyut nadi normal. Nilai VO2maks menunjukkan 1 orang (8,33%) memiliki kebugaran kardiorespirasi yang baik, sebanyak 10 orang (83,34%) memiliki kebugaran kardiorespirasi pada kategori cukup. Didapatkan sebanyak 1 orang (8,33%) yang memiliki kebugaran kardiorespirasi buruk dan sudah kami sarankan untuk melakukan pemeriksaan lanjutan ke pelayanan kesehatan. Kami menyarankan untuk perlu adanya pengontrolan kebugaran kardiorespirasi secara teratur dan juga dibutuhkan pemberian edukasi kepada masyarakat tentang pentingnya melakukan pemeriksaan kardiorespirasi dan aktivitas fisik agar resiko terjadinya hipertensi rendah.Abstract: Cardiorespiratory fitness examinations are an effort to improve health and early detection of heart disease, including hypertension, in the community. Considering that hypertension is a lifetime risk disease and a silent killer, early detection activities are essential to reduce the risk of death due to complications. This Community Service Activity (CSA) aims to conduct health checks and cardiorespiratory fitness levels in the community, especially the young age group. This activity is carried out using the health check method (anamnesis, resting pulse rate, and blood pressure (BP)) and cardiorespiratory fitness checks by measuring the Maximum Oxygen Volume (VO₂ max) value. The partners in this CSA activity are a group of young men (aged 19-22 years) totaling 12 people in Banda Aceh. Evaluation of blood pressure examination results is normal if the systolic value is <120 mmHg and diastolic <80 mmHg. The results show that twelve people have normal blood pressure and pulse. The VO2max value shows that one person (8.33%) has good cardiorespiratory fitness, and ten people (83.34%) have cardiorespiratory fitness in the sufficient category. It was found that one person (8.33%) had poor cardiorespiratory fitness, and we have recommended further examination to health services. We suggest that regular cardiorespiratory fitness monitoring is needed, and public education is also needed about the importance of conducting cardiorespiratory examinations and physical activity to reduce the risk of hypertension.
ANTICANCER ACTIVITY OF ETHANOL EXTRACT OF YELLOW ROOT (Arcangelisia flava) ON HEPG2 HEPATOCELLULAR CANCER CELLS Yusuf, Hanifah; Fahriani, Marhami; Murzalina, Cut
Jurnal Kedokteran Hewan Vol 16, No 1 (2022): March
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v16i1.23615

Abstract

This study aimed to evaluate anticancer activity and apoptosis induction of ethanolic extract of Arcalengisia flava (AF) roots on HepG2 cancer cell lines. The AF roots were extracted by maceration using ethanol 80%. MTT assay method was used to evaluate the anticancer activity and the proliferation of HepG2 cells. Flow cytometry method was used to assess the induction of HepG2 cells apoptosis. This study showed that the IC50 of AF ethanol extract against HepG2 cells was 109.14 g/ml. With IC50 treatment, the apoptosis assay showed a significant decrease in intact cells (80.101.7%) and a significant increase in early apoptosis (7.90.7%) and late apoptosis cells of HepG2 cancer cells (4.90.35%) compared to control cells. Moreover, the proliferation of HepG2 cells was declined significantly in 48 and 72 hours after treatment with IC50 (77.55.76% and 64.35.37%, respectively) and 2xIC50 of the extract (75.91.79% and 70.54.27%, respectively). This research suggests that the ethanolic extract of AF roots can potentially be used for hepatocarcinoma treatment.
Co-Authors Alia, Dina Annisa, Siti Nur Desiana , Desiana Elvia, Elvia Fahriani, Marhami Farhana, Rika Gartika Setiya Nugraha Hanifah Yusuf Munadi Munadi Ratna Idayati, Ratna Razali, Rezania Safrizal Rahman, Safrizal Shidqi, Muhammad T.R, T. Husni Teuku Romi Imansyah Putra Yusni Yusni Zakiaturrahmi, Zakiaturrahmi