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POTENSI ANTIJAMUR EKSTRAK KAYU MANIS TERHADAP JAMUR Candida albicans PENYEBAB ORAL CANDIDIASIS Yuditha, Solva; Larasati, Lisya Bella Putri
M-Dental Education and Research Journal Vol 2, No 2 (2022): M-Dental Education and Research Journal
Publisher : Fakultas Kedokteran Gigi Universitas Prof. Dr. Moestopo (Beragama)

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ABSTRAKLatar Belakang: Suatu penelitian menyatakan sebanyak 20-75% Candida albicans pada populasi umum menjadi Candida carriers atau tanpa menimbulkan gejala. Candida albicans pada keadaan patogen menjadi agen penyebab primer oral candidiasis. Terapi oral candidiasis yang paling sering adalah menggunakan obat antijamur seperti flukonazol dan nystatin. Penggunaan antijamur konvensional dalam jangka panjang dan ekstensif memicu peningkatan resistensi sehingga dilakukan pencarian agen pengobatan alternatif dengan toksisitas yang lebih rendah seperti kayu manis. Kayu manis (Cinnamomum burmannii) mengandung senyawa kimia flavonoid yang berpotensi sebagai agen antijamur alami terhadap Candida albicans. Tujuan: Menganalisis potensi antijamur ekstrak kayu manis terhadap jamur Candida albicans penyebab oral candidiasis. Metode: Menganalisis delapan (8) jurnal dari database PubMed, Google Scholar, dan NCBI. Penelitian yang dianalisis mengenai potensi antijamur kayu manis terhadap jamur Candida albicans penyebab oral candidiasis. Kesimpulan: Kayu manis berpotensi sebagai agen antijamur terhadap Candida albicans dengan cinnamaldehyde dari golongan flavonoid sebagai senyawa kimia aktif yang paling berperan. Konsentrasi minimum kayu manis dapat menghasilkan zona hambat yang cukup besar terhadap Candida albicans. Kayu manis sebagai bahan herbal ternyata juga memiliki efek samping, sehingga keamanan dari agen antijamur alami ini tetap harus diperhatikan. ABSTRACTBackground: According to research, as many as 20-75% of Candida albicans in the general population become Candida carriers or asymptomatic. Candida albicans in pathogenic conditions becomes the primary causative agent of oral candidiasis. The most common treatment for oral candidiasis is the use of antifungal drugs such as fluconazole and nystatin. Long-term and extensive use of conventional antifungals leads to increased resistance, so the search for alternative medicinal agents with lower toxicity, such as cinnamon. Cinnamon (Cinnamomum burmannii) contains flavonoid chemical compounds that have the potential as natural antifungal agents against Candida albicans. Objective: To analyze antifungal potency of cinnamon extract against Candida albicans fungus that causes oral candidiasis. Methods: Analyzed eight (8) journals from the database like PubMed, Google Scholar, and NCBI. The study analyzed theantifungal potential of cinnamon against Candida albicans fungus that causes oral candidiasis. Conclusion: Cinnamon has potential as antifungal agents against Candida albicans with cinnamaldehyde from the flavonoid group as the most active chemical compound. The minimum concentration of cinnamon can produce a large enough zone of inhibition against Candida albicans. Cinnamon as an herbal ingredient also has side effects, so the safety of this natural antifungal agent remains to be considered.

THE EFFECT OF BLACK CUMIN (NIGELLA SATIVA L.) ON THE IMMUNE SYSTEM FOR ORAL HEALTH Dewi, Komang Krisna; Yuditha, Solva; Kusparmanto, Lukas; Purwoko, Winda Asha
Moestopo International Review on Social, Humanities, and Sciences Vol. 4 No. 2 (2024)
Publisher : Universitas prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/mirshus.v4i2.82

The immune system is a system that is able to protect the body from microorganisms that cause disease. This system can limit microbial colonization in the oral cavity and prevent the penetration of harmful substances. The immune system is related to health problems in the oral cavity. Black cumin (Nigella sativa L.) has the main active component, namely thymoquinone. Thymoquinone has an immunomodulatory, anti-inflammatory, analgesic, and antioxidant effect that shows an important role in oral disease management and also in oral health. Research shows that the substance thymoquinone in black cumin has an effect on increasing the immune system in the oral cavity. The research analyzed was research on the effect of black cumin on the immune system for oral health. The use of black cumin containing thymoquinone is effective for increasing the immune system in the oral cavity, if used at a concentration of 0.1%-0.2% and applied directly to the area that is experiencing inflammation. So it can be concluded that black cumin has an effect on increasing the immune system in the oral cavity.

LCMS ANALYSIS OF ROSELLA EXTRACTS (HIBISCUS SABDARIFFA LINN) Yuditha, Solva; Pakpahan, Evie Lamtiur; Kusparmanto, Lukas
Moestopo International Review on Social, Humanities, and Sciences Vol. 5 No. 1 (2025)
Publisher : Universitas prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/mirshus.v5i1.107

Rosella (Hibiscus sabdariffa Linn) is a traditional medicinal plant with more than 300 species distributed in tropical and subtropical regions. The plant is grown for its fibre as a medicinal ingredient. Rosella has various benefits due to its diverse chemical compounds, such as alkaloids, anthocyanins, flavonoids, tannins, steroids, and sterols. This study discussed the potential of rosella as an anti-inflammatory, antioxidant, antibacterial, antihypertensive, antidiabetic, and anticholesterol. To observe the chemical compound content of rosella flower extract. Methods: LCMS (Liquid Chromatography-Mass Spectrometry) test to see the content of chemical compounds in rosella flower extract. LCMS test showed that rosella flower extract contains flavonoids, tannins, phenolic-quinic acid, phenolic, and alkaloid chemical compounds. Rosella flower extract contains chemical compounds such as flavonoids, tannins, phenolics, quinic acid, and alkaloids, which have antibacterial, antioxidant, anti-inflammatory properties, as well as diuretic, anticholesterol, antidiabetic, and antihypertensive effects. These compounds give rosella great potential as a natural ingredient with various pharmacological applications. Although the results showed that rosella has many pharmacological benefits, further research is still needed to understand the deeper mechanisms and potential clinical use of rosella for the treatment of various diseases, especially in dentistry.

Penyuluhan Kesehatan Gigi dan Mulut Bagi Siswa di Kecamatan Sembalun, Lombok Timur, Nusa Tenggara Barat Yuditha, Solva; Kusparmanto, Lukas; Dewi, Komang Krisna
Jurnal Pustaka Dianmas Vol 2, No 2 (2022)
Publisher : Universitas Prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/dianmas.v2i2.2499

Dental and oral health is an important indicator to determine overall body health. Dental and oral health can affect the health of a person's body so efforts are needed to maintain good dental and oral health. This problem will result in the metabolic activity of bacteria and plaque which causes tooth decay, in the long term it will cause tooth loss and will eventually cause masticatory function disorders. Dental Alumni Association, Faculty of Dentistry, University of Prof. Dr. Moestopo (Beragama) Jakarta has the idea to carry out social service activities with the aim of participating in the success of government programs, especially the Ministry of Health to create caries free Indonesian society at the age of 12 which is targeted for 2030. Social service activities are carried out at SDN 1 and SMPN 1 Sembalun, East Lombok, West Nusa Tenggara with a target of 200 elementary school students and 207 junior high school students. The implementation method used is in the form of dental and oral health counseling, distribution of toothbrushes and toothpaste as well as joint tooth brushing activities in an effort to prevent dental caries by brushing the teeth properly.

EFFECTIVENESS OF USING VIDEO COMPARED TO OTHER MEDIA FOR DENTAL AND ORAL HEALTH EDUCATION Kusparmanto, Lukas; Yuditha, Solva
Moestopo International Review on Social, Humanities, and Sciences Vol. 3 No. 1 (2023)
Publisher : Universitas prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/mirshus.v3i1.48

Dental health education for children aims to introduce them to the world of dental health and address issues related to teeth. One of the recommended method is through video viewing, which can captivate children's attention, particularly when animated videos are used. This study analyzes the effectiveness of video viewing in improving target knowledge and compares it with other methods. This research involved analyzing national and international books and journals that explore the use of videos as a teaching tool for dental health education among elementary school-age children. Results show videos are highly effective in enhancing children's knowledge of proper teeth brushing. They outperform other methods such as flip charts, leaflets, and posters. When compared to alternative educational methods, videos are almost as effective as hand puppets. However, flip charts, leaflets, and posters remain viable options for dental and oral health education among elementary school children, as they have proven to be effective.

OVERVIEW OF KNOWLEDGE OF HALITOSIS AMONG EMPLOYEES IN FACULTY OF DENTISTRY, MOESTOPO UNIVERSITY Yuditha, Solva; Kusparmanto, Lukas; Maharani, Hairunisza Putri
Moestopo International Review on Social, Humanities, and Sciences Vol. 3 No. 2 (2023)
Publisher : Universitas prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/mirshus.v3i2.57

Background: Halitosis is an unpleasant mouth odor exhaled during breathing. Approximately 80% of halitosis can originate from the oral cavity, while about 10-20% may arise from sources outside the oral cavity. Halitosis has psychological impacts on individuals, leading to poor social communication and reduced social activities. Objective: To assess the overview of knowledge and information regarding halitosis among employees in the environment of Faculty of Dentistry, Moestopo University. Methods: This study employs a descriptive research design with a cross-sectional approach. The sampling technique employed is Purposive sampling, the sample size consists of 58 respondents who participated in the study through a questionnaire distributed using Google Forms and paper-based formats, consisting of 15 closed-ended questions. Respondents’ knowledge is categorized into three levels: good, fair, and poor. Results: Based on the distributed questionnaires, 30 respondents (51.7%) demonstrated good knowledge, 18 respondents (31%) had fair knowledge, and 10 respondents (17.2%) exhibited poor knowledge of halitosis. Conclusion: the analysis data concerning the overview of halitosis knowledge among employees in the environment of Faculty of Dentistry, Moestopo University, it can be concluded that the knowledge of halitosis among employees in the Faculty of Dentistry, Moestopo University environment is categorized as good, with a percentage (51.7%).

STUDY IN THE POTENTIAL OF CHEMICAL COMPOUNDS OF ROSELLA FLOWER (HIBISCUS SABDARIFFA LINN) EXTRACT AS A PREVENTION OF RELAPSE AFTER ORTHODONTIC TREATMENT Kusparmanto, Farhany Sefina; Pakpahan, Evie Lamtiur; Yuditha, Solva; Kusparmanto, Lukas
Moestopo International Review on Social, Humanities, and Sciences Vol. 4 No. 1 (2024)
Publisher : Universitas prof. Dr. Moestopo (Beragama)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32509/mirshus.v4i1.71

In dentistry, we can correct malocclusion and malposition by moving the teeth with orthodontic treatment. After the orthodontic treatment is done there’ll still be a possibility of relapse. Relapse is when the teeth return to their original position before the orthodontic treatment was done. The prevalence of relapse after orthodontic treatment is still quite high. Relapse prevention can be achieved through the use of mechanical devices but, they have some limitations. Natural materials can be used as an alternative as the prevention method that can prevent the relapse from happening. Roselle extract contains chemical compounds that have the potential to prevent relapse after the orthodontic treatment is done. To observe the potential of chemical compounds in roselle flower extract as a relapse prevention method after orthodontic treatment. This research was a laboratory experiment. The research phase began with the extraction of rosella flowers (Hibiscus sabdariffa Linn), then continued with the second stage, namely the phytochemical screening of rosella flowers (Hibiscus sabdariffa Linn) using the color reaction method. The phytochemical tests showed that the roselle flower extract contains chemical compounds such as flavonoids, tannins, and saponins. Conclusion: The roselle flower extract contains chemical compounds such as flavonoids, tannins, and saponins, which have anti-inflammatory and antioxidant properties, making it potentially effective in preventing relapse after orthodontic treatment.

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