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All Journal Cermin Dunia Kedokteran Jurnal Ilmiah Kesehatan (JIKA)
Suseno, Endy
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Health Professions Medicine & Pharmacology Nursing Public Health

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Peran Vaksinasi dalam Pencegahan Herpes Zoster Adiwinata, Randy; Suseno, Endy
Cermin Dunia Kedokteran Vol 43, No 6 (2016): Metabolik
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (89.29 KB) | DOI: 10.55175/cdk.v43i6.71

Abstract

Herpes zoster lebih sering terjadi pada kelompok usia di atas 50 tahun. Neuralgia pascaherpetika menjadi salah satu komplikasi tersering dan dapat menetap selama bertahun-tahun. Pengobatan neuralgia pascaherpetika saat ini belum adekuat. Pemberian vaksin herpes zoster menjadi strategi efektif untuk mengurangi insidens herpes zoster dan neuralgia pascaherpetika. Di Indonesia, vaksin herpes zoster telah direkomendasikan untuk seluruh individu berusia lebih dari 50 tahun.
Blood Urea Nitrogen-Serum Albumin Ratio As a Predictor of Clinical Outcome in Acute Ischemic Stroke Suseno, Endy; Akbar, Muhammad; Bintang, Andi Kurnia; Soraya, Gita Vita; Lotisna, Mimi; Sompa, Andi Weri
Jurnal Ilmiah Kesehatan (JIKA) Vol. 6 No. 1 (2024): Volume 6 Nomor 1 April 2024
Publisher : Sarana Ilmu Indonesia (salnesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36590/jika.v6i1.573

Abstract

Stroke is a global health issue with high morbidity and fatality rates. Treatment decisions for ischemic stroke rely on clinical outcome prediction. The NIHSS score is commonly used to predict the AIS's clinical outcomes. However, its use is hindered by its complexity, which requires the assessment of many variables. Therefore, there is an urgent need to develop a simpler yet still effective evaluation tool in assessing the AIS’s clinical outcome. The study aimed to predict AIS outcomes using the blood urea nitrogen to albumin serum ratio (RBA). This study was a prospective cohort study design, with subjects being first-time AIS patients hospitalized at RSUP Dr. Wahidin Sudirohusodo and several hospitals in Makassar from December 2022–April 2023. Demographic and clinical data were collected, assessing RBA and comparing it according to the good (mRS 0-2) and poor (mRS 3-6) outcome groups. RBA performance was assessed by receiver operating characteristic curve (ROC) analysis to assess the AIS's clinical outcome. The study's findings on 62 participants meeting the criteria revealed a significant association between RBA and the AIS's clinical outcome (p-value=0,0004). The mean RBA differed significantly between the good and poor AIS outcome groups (p-value =0,006). In the ROC analysis, the area under the curve (AUC) was 0,75 with an optimal cut-off value was 2,05, yielding a sensitivity of 41,67%, a specificity of 98%, and a likelihood ratio of 20,83 (p-value=0,007). In conclusion, RBA can be used as a simple and objective tool to determine the clinical outcome predictors of AIS.
Co-Authors Andi Kurnia Bintang, Andi Kurnia Lotisna, Mimi Muhammad Akbar Randy Adiwinata, Randy Sompa, Andi Weri Soraya, Gita Vita