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All Journal Cermin Dunia Kedokteran Makara Journal of Health Research The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Penyakit Dalam Indonesia
Randy Adiwinata, Randy
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Health Professions Medicine & Pharmacology Public Health

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Masalah Virus Zika pada Kehamilan Richard, Timoteus; Kristanto, Andi; Adiwinata, Randy; Stephanie, Aurelia; Christianty, Finna; Belinda Phang, Beatrice; Adiwinata, Sheila
Cermin Dunia Kedokteran Vol 43, No 5 (2016): Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (129.895 KB) | DOI: 10.55175/cdk.v43i5.57

Abstract

Wabah Virus Zika (ZIKV) merebak pada tahun 2015 hingga 2016 terutama di benua Amerika dan mendapat perhatian dunia. ZIKV merupakan penyakit yang ditularkan oleh nyamuk Aedes, umumnya self limiting dan jarang fatal pada dewasa. Perhatian lebih kepada ibu hamil karena potensi janin mikrosefalus. Centers for Disease Control and Prevention (CDC) telah mengeluarkan beberapa rekomendasi diagnosis dan manajemen ZIKV baik pada ibu hamil maupun pada bayi baru lahir. Pencegahan dan diagnosis dini ZIKV menjadi kunci utama penanganan.
Peran Vaksinasi dalam Pencegahan Herpes Zoster Adiwinata, Randy; Suseno, Endy
Cermin Dunia Kedokteran Vol 43, No 6 (2016): Metabolik
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (89.29 KB) | DOI: 10.55175/cdk.v43i6.71

Abstract

Herpes zoster lebih sering terjadi pada kelompok usia di atas 50 tahun. Neuralgia pascaherpetika menjadi salah satu komplikasi tersering dan dapat menetap selama bertahun-tahun. Pengobatan neuralgia pascaherpetika saat ini belum adekuat. Pemberian vaksin herpes zoster menjadi strategi efektif untuk mengurangi insidens herpes zoster dan neuralgia pascaherpetika. Di Indonesia, vaksin herpes zoster telah direkomendasikan untuk seluruh individu berusia lebih dari 50 tahun.
A Clinical Profile of Hepatitis A Patients in Jakarta, Indonesia Adiwinata, Randy; Kristanto, Andi; Richard, Timoteus; Edbert, Daniel; Angelina, Frida; Eppy, Eppy; Mauleti, Ifael Y; Lardo, Soroy; Firmansyah, Iman; Bur, Rika; Ahimsa, Titos; Nelwan, Erni J
Makara Journal of Health Research Vol. 21, No. 1
Publisher : UI Scholars Hub

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Abstract

Background: To determine the incidence of hepatitis A infections and the clinical profiles of adult patients admitted to public hospitals in Jakarta, Indonesia. Methods: This was a cross-sectional study that utilised consecutive secondary data from internal medicine wards of seven public hospitals in Jakarta between 2011 and 2013. Eligibility criteria included patients over the age of 18 years and an ICD-10 diagnosis code of B15, acute hepatitis A. Case proportion was reported per 1000 people by dividing incidence per year to total in-ward patients. Clinical profiles were reported descriptively. Laboratory results were compared and categorised into groups of patients aged below and above 25 years old. Results: Data revealed that hospitalisations of patients with hepatitis A had decreased from 2011 to 2013. 289 patients were studied, the majority were young adults (18-25 years old) and their common chief complaints were nausea (36%), fever (24%), and jaundice (21%). Higher bilirubin levels were seen in older patients. There were 13 patients coinfected with hepatitis B, one patient coinfected with hepatitis C, and one patient coinfected with HIV. Conclusions: The proportion of hepatitis A infection amongst adults admitted to public hospitals in Jakarta was low and had decreased during the study period. Most of the patients reported classical clinical manifestations. This study found that the targeted age group may benefit from receiving routine hepatitis A vaccinations.
Tatalaksana Terkini Perlemakan Hati Non Alkoholik Adiwinata, Randy; Kristanto, Andi; Christianty, Finna; Richard, Timoteus; Edbert, Daniel
Jurnal Penyakit Dalam Indonesia Vol. 2, No. 1
Publisher : UI Scholars Hub

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Abstract

Perlemakan Hati Non Alkoholik (Non Alcoholic Fatty Liver Disease/NAFLD) merupakan salah satu penyebab utama dari penyakit hati kronis di negara berkembang. NAFLD dapat berkembang menjadi menjadi penyakit hati yang lebih berat seperti Non Alcoholic Steatohepatis (NASH), sirosis hepatis, dan karsinoma hati. Tatalaksana NAFLD terus berkembang, dan saat ini klinisi dihadapkan dengan berbagai pilihan alternatif baik dari segi nonfarmakoterapi maupun farmakoterapi. Tulisan ini akan membahas berbagai pilihan terapi NAFLD terkini tersebut berdasarkan bukti terbaru.
Manajemen Koinfeksi Malaria Berat dengan HIV Belum Mendapat Terapi Antiretrovirus di Era Pandemi COVID-19: Sebuah Laporan Kasus Harijanto, Paul; Mawuntu, Rosye; Rusli, Novia; Adiwinata, Randy; Nugroho, Agung
Jurnal Penyakit Dalam Indonesia Vol. 10, No. 3
Publisher : UI Scholars Hub

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Abstract

Severe malaria is a serious infectious disease that required immediate diagnosis and prompt treatment. Severe malaria may result several organ failures which is similar with other infectious diseases like SARS-CoV-2, sepsis, dengue, and HIV infection. Most of those infection have similar symptoms such as fever, myalgia, and headache, therefore physician should have high suspicion regarding co-infection with other infectious agents. The overlapping symptoms of co-infections may become a challenge for physician in diagnosing and delivering prompt therapy. Failure to deliver prompt treatment may lead to fatal outcome such as in severe malaria case. Stigmatization of all patients with fever and cough for COVID-19, may lead to misdiagnosis, moreover in some facilities which SARS-COV-2 PCR testing may not readily available to rule out infection. Therefore, it is importance to have broad differential diagnosis of fever during COVID-19 pandemic era, including the possibility of malaria infection in immunocompromised patients This can be achieved by comprehensive history taking and physical examination in evaluating patients with fever. We report antiretroviral naïve HIV infected patient with severe malaria indicated by several multi organ damage that successfully treated.
Asparaginase-Induced Acute Necrotizing Pancreatitis Resulting in Chronic Pancreatitis and Pseudocyst in an Adult with Acute Lymphocytic Leukemia Adiwinata, Randy; Waleleng, Bradley Jimmy; Haroen, Harlinda; Rotty, Linda; Gosal, Fandy; Rotty, Luciana; Hendratta, Cecillia; Lasut, Pearla; Winarta, Jeanne; Waleleng, Andrew; Tendean, Michael
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 1 (2023): VOLUME 24, NUMBER 1, April, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/241202398-101

Abstract

L-Asparaginase is one of the main chemotherapy regiments for acute lymphocytic leukemia (ALL) management. Acute pancreatitis is one of the serious side effects of l-asparaginase administration and may lead to interruption of chemotherapy cycle. Long term complications may be devastating for patients which include of pseudocyst pancreas and chronic pancreatitis. Asparaginase induced pancreatitis is rare among adult due to the nature of ALL which commonly occurred in children population. The pathophysiology of asparaginase induced pancreatitis is still unclear. Here we present 18-year-old male with ALL and asparaginase induced acute necrotizing pancreatitis which complicated to chronic pancreatitis and pseudocyst. 
The Prevalence and Risk Factors of Gastric Polyp in Endoscopy Unit at Prof. Dr. R.D. Kandou Hospital Adiwinata, Randy; Andriani, Janette; Soetanto, Raynold; Waleleng, Andrew; Winarta, Jeanne; Rotty, Luciana; Gosal, Fandy; Tendean, Nelly; Waleleng, Bradley Jimmy
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 24, No 1 (2023): VOLUME 24, NUMBER 1, April, 2023
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/241202335-40

Abstract

Background: Gastric polyps are usually asymptomatic; they are often incidentally discovered during an esophagogastroduodenoscopy (EGD) for other indication. Most of gastric polyps are benign, however, some have malignant potential. Therefore, identifying gastric polyp risk factors are crucial. This article aims to determine the prevalence and risk factor of gastric polyp in Endoscopy Unit at Prof. Dr. R.D. Kandou Hospital between April 2021-2022.Method: The retrospective study was using medical record data of all patients who underwent EGD between April 2021-2022. Data regarding patient’s characteristic, endoscopic finding, and risk factors were collected. Data was analyzed using SPSSv25.0 with Mann-Whitney, Chi-square-test, and logistic-regression.Results: There were 241 patients included, 56.4% were males. The median age was 53 years old. The most common symptom was epigastric pain (69.3%). The main indication of EGD was dyspepsia with alarm symptoms (79.25%). We found 24.1% of patients had gastric polyps. Most polyps were found in corpus (93.1%) and 70.7% were fundic gland polyp. We found that older age (p=0.001), female (p=0.003), gastritis (p=0.037), active-smoker (p=0.000), and one-year-PPI-usage (p=0.000) were significantly associated with gastric polyp. Logistic-regression analysis showed active smoking was the most significant risk factor (OR=9.3), followed by female gender (OR=6.4), and PPI-usage (OR=3.4). We found no significant association between esophagitis, bile-reflux, gastric ulcer, H. pylori infection, NSAID use, and alcohol abuse with gastric polyp.Conclusions: We found 24.1% gastric polyp prevalence with significant risk factors such as older age, female gender, gastritis, smoking, and long-term-PPI-usage.
Co-Authors Adiwinata, Sheila Adiwinata, Sheila Ahimsa, Titos Andi Kristanto Andriani, Janette Angelina, Frida Ari Fahrial Syam Belinda Phang, Beatrice Benny N Kurniawan, Benny N Bradley Jimmy Waleleng Daniel Edbert, Daniel Eppy Eppy Erni J Nelwan, Erni J Fandy Gosal Finna Christianty, Finna Harijanto, Paul Harlinda Haroen Hendratta, Cecillia Iman Firmansyah Linda Rotty Luciana Rotty, Luciana Marcellus Simadibrata Mauleti, Ifael Y Mawuntu, Rosye Nugroho, Agung Pearla Lasut Phang, Beatrice Belinda Rasidi, Josephine Rika Bur Robert Sinto Rusli, Novia Silvia Suminto, Silvia Simatupang, Emerson Patulahon Soetanto, Raynold Soroy Lardo Stephanie, Aurelia Suseno, Endy Tendean, Michael Tendean, Nelly Timoteus Richard, Timoteus Waleleng, Andrew Willy Brodus Uwan, Willy Brodus Winarta, Jeanne