Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Pharmaceutical Sciences and Research (PSR) Makara Journal of Science
Tambunan, Usman Sumo Friend
Unknown Affiliation

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Optimasi Biotransformasi Total Sterol Limbah Tahu Menggunakan Mycobacterium phlei DSM 43286 Menjadi 1,4-Androstadien-3,17-Dion, Dengan Pengaruh Variasi Konsentrasi Inhibitor A, A’- Dipiridil Kurniadi, Maryati; Tambunan, Usman Sumo Friend; Harmita, Harmita
Majalah Ilmu Kefarmasian Vol. 1, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Isolation of total sterol from waste product of soy bean cake has been conducted, followed by biotransformation to 1,4-androstadien-3,17-dione (ADD). The waste product consist of; β-sitosterol, stigmasterol, kaemfesterol, which are isolated by column chromatography technique using silica gel as stationary phase and chloroform as mobile phase. Biotransformation was conducted by using Mycobacterium phlei DSM 43286 in the present of α, α’- dipiridil as an inhibitor with concentration of 0,5; 1; 1,5; 2,0 mM. The main product of biotransformation were ADD and pregnenolon. The optimum yield of ADD 0,48% is achieved by adding 1,5 mM α, α’- dipiridil are two hours after addition of substrate and 72 hours of incubation time.
STUDI IN SILICO MODIFIKASI POS TRANSLASI DISAIN VAKSIN CHIMERIC BERBASIS VIRUS LIKE PARTICLES HUMAN PAPILLOMAVIRUS DENGAN KAPSID VIRION L1 Tambunan, Usman Sumo Friend; Parikesit, Arli Aditya; Tochary, Theo A.; Sugiono, Dedy
Makara Journal of Science Vol. 11, No. 2
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Computational Study of Post Translation Modification in Chimeric Virus Like Particles Vaccine of Human Papilloma Virus with Virion Capsid L1. The Human Papillomavirus (HPV) infection has a tight correlation with the incidence of cervical cancer. Chimeric virus like particles (cVLP) has been developed as vaccine candidate for preventing cervical cancer. cVLPs are improvement of Virus Like Particles (VLP) by substituting the epitope of L1 HPV -18 and -52 protein to L1 HPV -16 protein. They are ANN1, ANN2, HMM1, and HMM2. The impact of post translation modification will be determined. Based on In Silico study, the dominant post translation modification is glycosylation
Co-Authors Arli Aditya Parikesit Harmita Harmita, Harmita KRISTIAWAN, ONIE Maryati Kurniadi Sugiono, Dedy Tochary, Theo A.