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All Journal Jurnal Mandala Pharmacon Indonesia Journal of Pharmaceutical and Sciences. Jurnal Pengabdian Masyarakat Panacea Strada Journal of Pharmacy
Julianti, Tri Budi
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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Edukasi Penyakit Asam Urat di Desa Dawung Wetan Surakarta Wikantyasning, Erindyah Retno; Wahyuni, Arifah Sri; Julianti, Tri Budi; Amalia, Nastity Zhahwa; Astuti, Devi Dwi
Jurnal Pengabdian Masyarakat Panacea Vol 2, No 4 (2024): Jurnal Pengabdian Masyarakat Panacea
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jpmp.v2i4.14143

Abstract

Prevalensi penyakit tidak menular, termasuk asam urat, semakin meningkat di Indonesia. Pengabdian kepada masyarakat ini menguraikan pelaksanaan kegiatan pengabdian kepada masyarakat yang difokuskan pada penyuluhan penyakit asam urat di Kelurahan Dawung Wetan, Kota Surakarta, Provinsi Jawa Tengah. Penyuluhan ini bertujuan untuk meningkatkan pemahaman masyarakat tentang penyakit asam urat dan mendorong praktik hidup sehat. Metodologi yang digunakan adalah penyuluhan tentang faktor risiko penyakit asam urat kepada ibu-ibu PKK. dan pencegahan penyakit, dilanjutkan dengan sesi tanya jawab, pemberian pretest sebelum penyuluhan, dan posttest setelah penyuluhan untuk menilai tingkat pengetahuan masyarakat. Hasil penelitian menunjukkan bahwa 66,7% peserta memiliki pemahaman yang komprehensif tentang asam urat, sedangkan 33,3% menunjukkan pengetahuan yang memadai. Temuan ini menunjukkan bahwa edukasi yang disampaikan memberikan pemahaman ibu-ibu PKK tentang asam urat meningkat terlihat dari jawaban pretest dan posttest yang diberikan. Meskipun demikian, temuan ini juga memberikan arahan untuk meningkatkan inisiatif edukasi dan pencegahan. Upaya pengabdian masyarakat ini secara efektif meningkatkan pengetahuan masyarakat tentang asam urat dan mendorong penerapan gaya hidup sehat. untuk mewujudkan masyarakat yang lebih sejahtera dan berkualitas. Kata Kunci: Edukasi, Asam Urat, Gaya Hidup Sehat, Kesehatan The prevalence of non-communicable diseases, including gout, is rising in Indonesia. This community service outlines the execution of community service initiatives centred on gout education in Dawung Wetan Village, Surakarta City, Central Java Province. This counselling seeks to enhance public comprehension of gout and encourage healthy lifestyle practices. The methodology entails instructing PKK moms on risk factors and disease prevention, succeeded by a question and answer session, the administration of a pretest prior to counselling, and a posttest subsequent to counselling to assess the community's knowledge level. The findings indicated that 66.7% of participants possessed a comprehensive awareness of gout, whilst 33.3% demonstrated adequate knowledge. These findings suggest educational initiatives aimed at enhancing public comprehension of gout. Nonetheless, these findings also offer direction for enhancing educational and preventive initiatives. This community service effort effectively enhances public knowledge about gout and promotes the adoption of healthy lifestyles to cultivate a more prosperous and quality society.
Water Hyacinth Extract in Herbal Medicine Development: Literature Review Sayutri, Zelvisya; Rahmawati Safitri; Raodhatul Jannah; Rahma Azkiah; Julianti, Tri Budi
Strada Journal of Pharmacy Vol. 7 No. 2 (2025): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v7i2.242

Abstract

Indonesia is a country with an extraordinary wealth of flora, one of which is water hyacinth (Eichhornia crassipes) which has been known as an invasive aquatic weed. Recent studies have shown this plant has potential as a raw material for herbal medicine. The purpose of this review is to evaluate the pharmacological activity and phytochemical content of water hyacinth based on current scientific literature. The method used was journal search and selection from 2021 to 2025 through PubMed, Google Scholar and ResearchGate databases with the keywords “Eichhornia crassipes”, ‘pharmacology’, and “bioactivity”. The results review showed water hyacinth extract has anti-inflammatory activity through decreasing proinflammatory cytokines, antidiabetic through activating SUR-1, GLP-1R, AMPK, and OCT-1 receptors and antibacterial against Prevotella intermedia and Staphylococcus aureus. In addition, anticancer activity was demonstrated through binding of active compounds to MCF-7 cancer cell receptors, as well as cytoprotective activity against oxidative stress in rat liver cells.
Uji Efektivitas Antihiperurisemia Ekstrak Etanol Kencur (Kaempferia galanga L.) dan Jahe Hitam (Kaempferia parviflora) terhadap Tikus yang Diinduksi Jus Hati Ayam dan Potassium Oxonate Wikantyasning, Erindyah Retno; Wahyuni, Arifah Sri; Julianti, Tri Budi; Putri, Nastity Zhahwa Amalia; Astuti, Devi Dwi
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 3 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i3.497

Abstract

Hyperuricemia is caused by excessive production and/or poor elimination of uric acid. Kencur (Kaempferia galanga L.) and black ginger (Kaemperia parviflora) can be utilised as antihyperurisemic alternatives because their flavonoids block xanthin oxidase (XO). The study determine the efficacy of black ginger ethanol extract (EEJH) as an in vivo antihyperuricemic agent. This research was conducted to determine the effectiveness of kencur ethanol extract (EK) dan black ginger ethanol extract (EEJH) as an antihyperuricemia in vivo. A complete random design used involving 32 mice in 8 groups. Negative control (CMC Na 0.5%); positive control (Allopurinol 10 mg/kgBW); EK and EEJH respectively 12.5; 25; and 50 mg/kgBW. Hyperurisemia was induced by chicken liver juice 4 mL/200 gBB p.o. and potassium oxonate 250 mg/kgBB i.p. UA monitoring was carried out before induction, 0, 7, and 14 days after treatment. Tukey post hoc tests and ANOVA were used to evaluate the data. The results indicate that both of EK and EEJH can reduced UA (p<0.05) however the reduction is significant with Allopurinol (P<0.05). Thus, it can be inferred that the EK and EEJH have potential for enhanced antihyperurysemic in decreasing the UA.
Formulasi dan Evaluasi Fisik Granul Effervescent Kombinasi Ekstrak Stenochlaena palustris dan Psidium guajava L. dengan Variasi Konsentrasi Asam sebagai Suplemen Ibu Hamil Hairunisa, Indah; Nurjunnah, Rika; Julianti, Tri Budi
Jurnal Mandala Pharmacon Indonesia Vol. 11 No. 2 (2025): Jurnal Mandala Pharmacon Indonesia 
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v11i2.889

Abstract

Angka kematian ibu hamil di Indonesia masih tinggi, disebabkan oleh anemia dan komplikasi kehamilan akibat malnutrisi, seperti kekurangan zat besi, asam folat, dan kalsium. Suplemen yang tersedia umumnya memiliki rasa kurang menyenangkan dan bentuk yang kurang praktis, sehingga mengurangi kepatuhan konsumsi. Penelitian ini bertujuan untuk melakukan formulasi dan evaluasi sediaan granul effervescent kombinasi ekstrak Stenochlaena palustris (daun kelakai) dan Psidium guajava L. (jambu biji merah) dengan variasi konsentrasi asam sebagai suplemen zat besi dan asam folat alternatif untuk ibu hamil. Penelitian dilakukan secara eksperimental laboratorium dengan metode granulasi basah dan evaluasi fisik granul meliputi uji organoleptik, waktu alir, kecepatan alir, sudut diam, kandungan lembab, pH, waktu larut, ketinggian busa, dan waktu hilang buih. Hasil uji fitokimia menunjukkan bahwa kedua ekstrak kelakai dan jambu biji merah mengandung senyawa flavonoid, fenolik, tanin, dan alkaloid. Berdasarkan hasil yang didapatkan, Formula III (perbandingan asam sitrat dan asam tartrat (9:3)) menunjukkan hasil yang terbaik dalam beberapa parameter, seperti waktu larut tercepat (2,22±0,07 menit), waktu hilang buih tercepat (2,12±0,05 menit), kandungan lembab  0,60±0,20%, serta sudut diam 36,29±0°. Namun meskipun lebih unggul, terdapat parameter yang masih belum memenuhi syarat seperti waktu alir yang masih 25,15 ± 2,88 detik serta ketinggian busa 1,63±0,15 cm. Berdasarkan hal ini, formula III merupakan formula suplemen effervescent paling optimal namun masih perlu dilakukan optimasi lebih lanjut. Penelitian ini diharapkan dapat menjadi dasar awal pengembangan suplemen herbal untuk ibu hamil, namun perlu dilakukan uji lanjutan, seperti uji kandungan Fe  dan Ca2+, serta uji in vivo pada hewan uji untuk menilai keamanan (termasuk uji teratogenisitas) dan khasiatnya. Selain itu, perlu dilakukan uji stabilitas sediaan untuk memastikan mutu dan kestabilan produk.
Water Hyacinth Extract in Herbal Medicine Development: Literature Review Sayutri, Zelvisya; Rahmawati Safitri; Raodhatul Jannah; Rahma Azkiah; Julianti, Tri Budi
Strada Journal of Pharmacy Vol. 7 No. 2 (2025): October
Publisher : Universitas STRADA Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30994/sjp.v7i2.242

Abstract

Indonesia is a country with an extraordinary wealth of flora, one of which is water hyacinth (Eichhornia crassipes) which has been known as an invasive aquatic weed. Recent studies have shown this plant has potential as a raw material for herbal medicine. The purpose of this review is to evaluate the pharmacological activity and phytochemical content of water hyacinth based on current scientific literature. The method used was journal search and selection from 2021 to 2025 through PubMed, Google Scholar and ResearchGate databases with the keywords “Eichhornia crassipes”, ‘pharmacology’, and “bioactivity”. The results review showed water hyacinth extract has anti-inflammatory activity through decreasing proinflammatory cytokines, antidiabetic through activating SUR-1, GLP-1R, AMPK, and OCT-1 receptors and antibacterial against Prevotella intermedia and Staphylococcus aureus. In addition, anticancer activity was demonstrated through binding of active compounds to MCF-7 cancer cell receptors, as well as cytoprotective activity against oxidative stress in rat liver cells.
Co-Authors Amalia, Nastity Zhahwa Arifah Sri Wahyuni Astuti, Devi Dwi Erindyah Retno Wikantyasning Indah Hairunisa Nurjunnah, Rika Putri, Nastity Zhahwa Amalia Rahma Azkiah Rahmawati Safitri Raodhatul Jannah Sayutri, Zelvisya