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All Journal Ina Kidney Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED)
Nasution, Alwi Thamrin
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Severe Clinical Impact of Multiple Wasp Stings: A Case Report of Acute Kidney Injury Fauziyah, Hana; Nasution, Bayu Rusfandi; Nasution, Alwi Thamrin
Indonesian Journal of Kidney and Hypertension Vol 1 No 2 (2024): Volume 1 No. 2, August 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i2.137

Abstract

Wasp stings are prevalent in Indonesia and have occasionally resulted in fatalities. Wasp stings can potentially induce a small localized allergic response, systemic reactions, or even life-threatening illnesses. Receiving several stings from wasps can cause systemic inflammation, resulting in acute kidney injury. We present a case of a 51-year-old female who experienced severe renal impairment as a result of repeated wasp stings. Following the stings, the patient promptly obtained medical attention. However, on the second day after the incident, the patient's renal function declined and experienced anuria. The ultrasonography indicates the presence of nephritis. The patient presented with 103 sting wounds, which resulted in local reactions and were accompanied by systemic symptoms. The patient was administered high-dose steroids and underwent five intermittent hemodialysis sessions, which effectively restored their kidney function. Evidence of enhanced renal function was demonstrated through the restoration of normal urine production, elevated glomerular filtration rate, and significant clinical improvements in the patient. This case illustrates the severe impact on the kidney of a generalized wasp sting and the effect of promptly receiving medical treatment following an enormous wasp sting on the patient's prognosis. Initiating dialysis promptly is crucial for rapidly eliminating toxins and thus preserving renal function.
Correlation Between Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in Chronic Kidney Disease (CKD) Patients Undergoing Regular Hemodialysis at Haji Adam Malik General Hospital Medan Prianto, Dwi; Lubis, Wika Hanida; Nasution, Alwi Thamrin
Journal of Society Medicine Vol. 2 No. 5 (2023): May
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i5.49

Abstract

Introduction: Chronic Kidney Disease are related to inflammation and stress levels therefore depression is a predictor that will increase the morbidity and mortality of patients with chronic kidney disease undergoing hemodialysis. Method: This research is an analytical study with a cross-sectional design which carried out in Januari until February 2023, at Hemodialysis Installation of RSUP. H. Adam Malik. To analyze the correlation between the Depression Level and Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR), the Pearson correlation test was used if the data was normally distributed. If the data is not normally distributed, Spearman's correlation test is performed. Statistical analysis using 95% confidence level (p<0.05). Results: In this research, demographic characteristics of 85 patients with mean age of the patients was 49.56 years old with a standard deviation of 13.46. Based on Spearman rho test it was found that there was a significant correlation between RDW and the BDI II score with p value 0.003. The degree of correlation or r value was 0.318. This indicates that there is a weak correlation between the RDW score and the BD II score. Based on Pearson test it was found that there was a significant correlation between ESR and the BDI II score with p value 0.009. The degree of correlation or r value was 0.280. This indicates that there is a weak correlation between the ESR value and the BD II score. Conclusion: Level of depression were found to be correlated with Red Blood Cell Distribution Width (RDW) and Erythrocyte Sedimentation Rate (ESR) in CKD patients whose undergoing regular hemodialysis.
The Relationship Between Serum Ferritin Levels and Left Ventricular Function in Patients Undergoing Hemodialysis Harahap, Astry Amelia; Nasution, Alwi Thamrin; Isnanta, Rahmat
Journal of Society Medicine Vol. 2 No. 10 (2023): October
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i10.90

Abstract

Introduction: Left ventricular hypertrophy (LVH) is a common condition that often occurs in patients undergoing regular hemodialysis, and it is associated with a poor prognosis in these patients. The worsening of LVH symptoms in patients undergoing hemodialysis is the strongest predictor of sudden cardiac death in such individuals. The aim of this study was to determine the relationship between serum ferritin levels and left ventricular function in patients undergoing hemodialysis at RSUP Haji Adam Malik, Medan. Method: The design of this study is a cross-sectional study with consecutive sampling. The study population consists of patients undergoing regular hemodialysis, and the population includes patients who undergo regular hemodialysis in RSUP H. Adam Malik. Results: There was a significant relationship between hemoglobin, albumin, and serum ferritin levels with left ventricular function (p < 0.005). Hemoglobin showed a moderate positive correlation with LVEF (r = 0.477). The relationship between albumin and LVEF had a stronger correlation (r = 0.681). There was a strong and significant negative correlation between serum ferritin and LVEF (r = -0.961). Conclusion: A significant relationship was found between hemoglobin levels, albumin levels, mean serum ferritin level, and left ventricular function in hemodialysis patients. Hemoglobin and albumin showed a positive correlation with left ventricular function, while serum ferritin level had a significant and strong negative correlation with left ventricular function.
Correlation between Red Cell Distribution Width (RDW) with Kidney Function and Hematologic Parameters in Patients undergo Regular Hemodialysis Hutasuhut, Soraya Mourina; Nasution, Alwi Thamrin; M. Feldy Gazaly Nasution
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 2 No. 4 (2020): Journal of Endocrinology, Tropical Medicine, and Infectiouse Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (587.888 KB) | DOI: 10.32734/jetromi.v2i4.4732

Abstract

Background. Red cell distribution width (RDW) is a coefficient of variation in red blood cells that can decrease erythropoesis or increase the destructiveness of red blood cells. The objectives of research to determine the relationship of RDW as an inflammatory marker with renal function and hematological parameters in patients undergoing regular hemodialysis Method; Cross sectional research on 20 patients undergoing regular hemodialysis > 3 months in RSUP H Adam Malik Medan. Vital sign, antropometry and venous blood retrieval are performed shortly before hemodialysis. RDW measurement comes from the red blood cell distribution curve in hematological analysis and is an indicator of variation in red blood cell size. Result: out of 20 subjek studies, there were 13 men (65.0%) and 7 (35.0%) women The majority of subjects had comorbid diabetes mellitus 14 (70.0%), hypertension 4 (20.0%). The average length of time patients underwent hemodialysis was 24.45 ± 20.98 months. There is a significant correlation between RBW and creatinine, Hb, and neutropil (r: 0.519, p:0,019*; r: 0.497, p: 0.026*;r: 0.464, p: 0.039*, respectively) Conclusion: There is a significant relationship between RBW and creatinine, Hb and neutropphils in patients undergoing regular hemodialysis > 3 months.
Correlation between Erythropoietin Resistance Index and Mortality in Regular Hemodialysis Patients at Haji Adam Malik General Hospital Medan Nasution, Fakhri Amin; Nasution, Alwi Thamrin; Nasution, Feldy G
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 2 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i2.12550

Abstract

Introduction: One of the functions of the kidneys is the production of erythropoietin, a signaling molecule that stimulates the production of red blood cells, in response to reduced oxygen levels in the blood. In chronic kidney disease, there is a disturbance in the production of erythropoietin. Several previous studies have linked the index of erythropoietin resistance to mortality in patients with chronic kidney disease. The study aimed to correlate between erythropoietin resistance index (ERI) and Mortality in regular hemodialysis patients. Method: Observational analytic study with a cross-sectional method to assess the relationship between ERI and mortality in all regular hemodialysis patients at H Adam Malik Medan. The ERI was used to evaluate erythropoietin EPO by comparing the dose of EPO to the hemoglobin level. The data were tested statistically with the Chi-Square method. Results: The average study subjects suffered from anemia with Hb levels of 8.21 g/dL, serum iron levels of 63.22 mcg/dL, and increased total iron-binding capacity (TIBC) levels with an average value of 190.2 mcg/dL, low ferritin levels of 195.59 mcg/L and serum transferrin (TSAT) 19.2%, and of 2.94 g/dL. Albumin levels, transferrin saturation, and ERI were associated with the mortality rate of patients undergoing regular hemodialysis (p=0.021; p=0.011; p=0.012). Conclusion: There is a relationship between the index of erythropoietin resistance and the mortality rate of patients undergoing regular hemodialysis
Co-Authors Fauziyah, Hana Harahap, Astry Amelia Hutasuhut, Soraya Mourina Isnanta, Rahmat Lubis, Wika Hanida M. Feldy Gazaly Nasution Nasution, Bayu Rusfandi Nasution, Fakhri Amin Nasution, Feldy G Prianto, Dwi