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All Journal JPBIO (Jurnal Pendidikan Biologi) Jurnal Mandala Pharmacon Indonesia Yumary: Jurnal Pengabdian kepada Masyarakat
Zainal, Tuti Handayani
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Humanities Economics, Econometrics & Finance Education Environmental Science Medicine & Pharmacology Social Sciences Other

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Uji Efektivitas Penyembuhan Luka Film Forming Gel Gentamisin pada Model Tikus Diabetes Zainal, Tuti Handayani; Nisa, Michrun; Hikma, Nurul; Astrid, Astrid; Arifin, Andi Ardiansyah
Jurnal Mandala Pharmacon Indonesia Vol. 10 No. 2 (2024): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v10i2.646

Abstract

Gentamisin paling banyak digunakan sebagai terapi infeksi pada ulkus diabetikum yaitu kelainan neurologi dan penyakit pembuluh darah arteri perifer yang merusak jaringan kulit terdalam dan menyebabkan infeksi, ulserasi, dan kerusakan kulit. Film Forming gel gentamisin memiliki keunggulan memiliki efek terapeutik, secara estetis lebih menarik bagi pasien, karakteristik yang tidak lengket, lebih oklusif dan dapat dirancang untuk menyediakan pelepasan obat yang berkelanjutan sehingga frekuensi penggunaan seminimal mungkin. Tujuan penelitian ini untuk mengetahui kandungan kadar gentamisin yang terjerap dalam polimer dan efektifitas penyembuhan luka diabetikum pada model tikus.  Tikus dibuat diabetes dengan induksi aloksan kemudian dibuat luka pada bagian punggung. Hewan uji dibagi dalam tujuh kelompok dan mendapatkan perlakuan basis film forming gel, salep gentamisin, film forming gel gentamisin dengan variasi polimer PVP dan PVA F1 (4: 10), F2 (3:11) dan F3 (2:12). Pengukuran kadar film forming gel menggunakan spektrofotometer UV-Vis dan efektifitas penyembuhan luka dilakukan dengan mengukur panjang luka dan lama penymbuhan. Hasil menunjukkan bahwa kandungan kadar film forming gel gentamisin pada F1 1,19 µg/mL, F2 1,80 µg/mL dan F3 1,44 µg/mL, efektifitas penyembuhan luka pada F 1 sembuh pada hari H-5, F2 H-6, F3 H-7 dan salep gentamisin H-10. Kesimpulan bahwa formula yang paling efektif terhadap luka diabetikus adalah F3 dengan konsentrasi PVP 2% dan PVA 12%.
Exploration of lactic acid bacteria from husk and black rice (Oryza sativa L) of toraja origin Hapiwaty, Saldi; Zainal, Tuti Handayani; Abidin, Hamdayani Lance; Utami, Yuri Pratiwi
JPBIO (Jurnal Pendidikan Biologi) Vol 10, No 2 (2025): November 2025
Publisher : STKIP Persada Khatulistiwa Sintang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31932/jpbio.v10i2.5529

Abstract

Lactic acid (LAB) is a bacteria involved in food fermentation and can be used as a probiotic to provide health benefits for those who consume it. This research aims to bring innovation and added value, and improve the community's utilization of probiotics (LAB) from husks and black rice from Toraja. The method used is collecting and processing samples, isolation and purification of LAB, microscopic and macroscopic identification, testing the activity/potential of LAB (Kirby Bauer), and molecular identification of 16S rRNA (sequencing). This study has confirmed that fermented rice has Lactococcus taiwanensis type lactic acid bacteria, while fermented husk is not a type of lactic acid bacteria. Lactococcus taiwanensis bacteria have probiotic potential and can produce antibacterial substances.
Peningkatan Keterampilan Pembuatan Sabun dan Lulur oleh Kelompok Budidaya Rumput Laut Zainal, Tuti Handayani; Maria, Maria Ulfa; Jamaludddin, Ruqayyah; Azmi, Nur; Saldy, Risky
Yumary: Jurnal Pengabdian kepada Masyarakat Vol 6 No 3 (2026): Maret
Publisher : Penerbit Goodwood

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35912/yumary.v6i3.5508

Abstract

Purpose: Seaweed possesses substantial potential but remains under-processed and underutilized. One of the products derived from seaweed is soap and body scrub. This community service activity aims to increase public understanding of seaweed, stimulate creative ideas, and equip participants with the basic skills for manufacturing seaweed-based products. Methodology/approach: The partner for this community service is the Pelita Makkio Baji Seaweed Cultivation Group in Ujung Baji Village, Takalar District, which involves 15 participants. The activity was conducted through training and mentoring in the production of soap and body scrub products. The participants’ understanding was measured through pre-tests and post-tests Results/findings: The pre-test indicated that the community’s knowledge of the benefits and innovations of seaweed was approximately 20 %, and after the activity (post-test), it reached 100 %. This activity also led to the creation of social media accounts as a marketing medium. Conclusions: Based on the above results, it can be concluded that community service activities have a significant positive impact on the community’s knowledge. Limitations: This study involved only a small number of participants from a single village; thus, the findings may not be generalizable to the wider community. Further activities involving more diverse groups and locations are recommended to strengthen the results Contributions: This program contributes to community empowerment by enhancing the ability of local seaweed farmers to innovate and manufacture seaweed-based products. It also provides a practical example of sustainable economic development through local resource utilization.
Co-Authors Abidin, Hamdayani Lance Andi Ardiansyah Arifin Astrid, Astrid Hapiwaty, Saldi Hikma, Nurul Jamaludddin, Ruqayyah maria, maria ulfa Michrun Nisa Nur Azmi, Nur Saldy, Risky Yuri Pratiwi Utami