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All Journal Indonesian Journal of Medicine Oto Rhino Laryngologica Indonesiana Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Askaroellah Aboet
Bagian Ilmu Kesehatan Telinga Hidung Tenggorok Bedah Kepala Leher Fakultas Kedokteran Universitas Sumatera Utara
Health Professions Medicine & Pharmacology Public Health

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The Diffrentiation of the Angles of Eustachian Tubes In the Patient Chronic Suppurative Otitis Media With and without Cholesteatoma Nasution, Rissa Ardika; Zahara, Devira; Aboet, Askaroellah
Indonesian Journal of Medicine Vol 2, No 1 (2017)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Chronic Suppurative Otitis Media (CSOM) is one of the major health problems found in many populations in the world and a cause of high morbidity and high mortality. However, there is no single theory that explains how and why chronic otitis media occurs. There are many studies on the function of Eustachian tube. However, the role of the Eustachian tube angle and the relationship with the occurrence of CSOM has not been widely studied. This study aimed to evaluate the mean of Eustachian tube angle and to examine the diffrentiation between angle of Eustachian tube in Chronic Suppurative Otitis Media (CSOM) patient with and without cholesteatoma. Subjects and Methods: This research is a case-control study. Study group consist of 27 patients of CSOM with cholesteatoma and 27 patients of CSOM without cholesteatoma included as controlling. All patients are examined by using CT temporal and measured the angle of Eustachian tube using Multiplanar Reconstruction (MPR) technique on osirix program. The data was analyzed using independent T testResults: The mean of the Eustachian tube angle in CSOM with cholesteatoma in female patients was 28.690 and male 27.780 whereas in the CSOM group without cholesteatoma in female patients was 33.810 and men 31.870. The mean of Eustachian tube angle in CSOM patients with cholesteatoma is 28.220 and CSOM without cholesteatoma is 33.000. In independent T test, the result showed significant differentiation (p= 0.001) between the angle of Eustachian tube in patients CSOM with and without cholesteatoma.Conclusion: The advance of technology makes easier to measure of Eustachian tube angle. In men found that the Eustachian tube angle is more horizontal than women. There is diffrence between the angle of the Eustachian tube with the occurrence of cholesteatoma in CSOM.Keywords: angle of Eustachian tube, CSOM Correspondence: Rissa Ardika Nasution. RSUP H. Adam Malik, Medan.  FK USU, Jln. Sembada Pasar V no. 27 P. Bulan Medan. Email: nrissaardika@yahoo.com. Mobile: 082277767660.Indonesian Journal of Medicine (2017), 2(1): 73-78https://doi.org/10.26911/theijmed.2017.02.01.08
Hubungan ekspresi RANKL dengan derajat destruksi tulang akibat kolesteatoma pada otitis media supuratif kronik Yarisman, Lilia; Asroel, Harry Agustaf; Aboet, Askaroellah; Zaluchu, Fotarisman
Oto Rhino Laryngologica Indonesiana Vol 47, No 1 (2017): Volume 47, No. 1 January - June 2017
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (978.71 KB) | DOI: 10.32637/orli.v47i1.189

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Latar belakang: Otitis media supuratif kronik (OMSK) dengan kolesteatoma merupakan penyakitpada telinga tengah dengan salah satu komplikasi berupa destruksi tulang, yang dapat menyebabkankematian. Receptor Activator of Nuclear Factor Kβ-Ligand (RANKL) merupakan salah satu sitokinyang berperan dalam proses destruksi tulang.Tujuan: Mengetahui hubungan ekspresi RANKL denganderajat destruksi tulang akibat kolesteatoma pada penderita OMSK tipe bahaya.Metode: Penelitian inibersifat analitik dengan desain cross sectional. Sebanyak 40 sampel kolesteatoma dilakukan pemeriksaanimunohistokimia untuk dinilai ekspresi RANKL pada kolesteatoma.Hasil: Terdapat hubungan yangsignifikan antara ekspresi RANKL dengan derajat destruksi tulang dan komplikasi yang terjadi (p<0,05).Tidak terdapat hubungan antara ekspresi RANKL dengan kelompok umur dan jenis kelamin (p>0,05).Kesimpulan: Terdapat hubungan yang signifikan antara derajat destruksi tulang dengan ekspresi RANKLmelalui pemeriksaan imunohistokimia.Kata kunci: RANKL, destruksi tulang, kolesteatoma, OMSK ABSTRACTBackground: Chronic suppurative otitis media (CSOM) with cholesteatoma is a middle ear disease,leading to bone structure destruction which can cause fatal case. Receptor Activator of Nuclear FactorKβ-Ligand (RANKL) is known as one of the cytokine that has important role in the process of bonedestruction.Purpose: To identify an association between RANKL expression with bone destruction leveldue to cholesteatoma in malignant CSOM patients. Method: This was an analytical study with crosssectional design. About 40 cholesteatoma sample was examinated by using immunohistochemistry tomeasure its RANKL expression. Result: There was a significant relationship (p<0.05) between RANKLexpression with bone destruction level and complication. There was no significant relationship betweenRANKL expression with age and sex (p>0.05). Conclusion: There was a significant relationship betweenbone destruction level with the RANKL expression by immunohistochemistry examination.Keywords: RANKL, bone destruction, cholesteatoma, CSOM
Profil Penderita Otitis Media Supuratif Kronis Asroel, Harry Agustaf; Siregar, Debi Rumondang; Aboet, Askaroellah
Kesmas Vol. 7, No. 12
Publisher : UI Scholars Hub

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Otitis media supuratif kronis merupakan penyakit telinga umum di negaranegara berkembang. Komplikasi otitis media supuratif kronis tipe bahaya mempunyai tanda dan gejala klinis yang khas.Tujuan penelitian ini adalah mengetahui profil penderita otitis media supuratif kronis (OMSK) tipe bahaya di RSUP H. Adam Malik. Penelitian deskriptif terhadap 119 penderita dari tahun 2006-2010. Sekitar 28,57% penderita dijumpai pada tahun 2010, sekitar 31,93% terjadi pada usia 11-20 tahun, sekitar 53,78% laki-laki, dan sekitar 38,66% pada telinga kanan. Sebanyak 68,91% terjadi akibat riwayat otitis media berulang dan 61,34% dengan keluhan utama telinga berair. Gejala dan tanda klinis yang sering terjadi adalah telinga berair (76,47%) dan perforasi membran timpani (74,79%), baik perforasi atik (0,84%), marginal (1,68%), subtotal (23,53%), dan total (48,74%). Gangguan pendengaran terbanyak adalah tuli konduktif (58,82%). Pada foto proyeksi Schuller, 62,18% dijumpai gambaran mastoiditis kronis dengan kolesteatoma. Dari hasil kultur dijumpai 21,01% Pseudomonas aeruginosa. 86,55% terjadi komplikasi mastoiditis.Profil penderita OMSK tipe bahaya di RSUP H. Adam Malik Medan sesuai dengan profil penderita OMSK tipe bahaya pada umumnya. Chronic suppurative otitis media (CSOM) is a common ear disease in developing countries. The complications of CSOM have a unique set of clinical signs and symptoms. This study aimed to identify the profile of dangerous type CSOM patients at H. Adam Malik General Hospital Medan in 2006-2010. A descriptive study of 119 patients in 2006-2010. From 119 patients, 28.57% were found in 2010, 31.93% were at age between 11-20 years old, 53.78% men and 38.66% were at right ear. 68.91% due to a history of recurrent otitis media and 61.34% with a main complaint of draining ears. The most clinical symptoms and signs were aqueous ears (76.47%) and tympanic membrane perforations (74.79%), as attic perforation (0.84%), marginal (1.68%), subtotal (23.53%), and total (48.74%). The most hearing impairments were conductive deafness (58.82%). In Schuller projections, 62.18% were found the imaging of chronic mastoiditis with cholesteatoma. From the culture results, 21.01% were Pseudomonas aeruginosa. 86.55% were mastoiditis complications. The profile of dangerous type CSOM patients at H. Adam Malik General Hospital Medan is similar with the other profile of dangerous type CSOM commonly.
Co-Authors Debi Rumondang Siregar Fotarisman Zaluchu, Fotarisman Harry Agustaf Asroel Nasution, Rissa Ardika Yarisman, Lilia Zahara, Devira