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All Journal Jurnal Riset Informatika Media Penelitian dan Pengembangan Kesehatan
Valentino, Albert Amadeus
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Environmental Science Medicine & Pharmacology

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TINJAUAN SISTEMATIS HISPATOLOGI GOUT ARTRITIS: PERAN SEL IMUN DALAM PROSES INFLAMASI DAN KERUSAKAN JARINGAN Larasati, Veny; Parisa, Nita; Valentino, Albert Amadeus; Diba, Msy. Farah
Media Penelitian dan Pengembangan Kesehatan Vol. 34 No. 4 (2024): MEDIA PENELITIAN DAN PENGEMBANGAN KESEHATAN
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/jmp2k.v34i4.2210

Abstract

Gout arthritis is a joint inflammation caused by increased uric acid levels, leading to the formation of monosodium urate (MSU) crystals. The study aimed to deepen the understanding of the role of MSU crystals in triggering both acute and chronic inflammatory responses, as well as the formation of tophi, which damage joint and bone tissues. The method used is the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The reviewed articles were obtained from the Science Direct, Semantic Scholar, and PubMed databases using the keywords “Gout Arthritis,” “Histopathology,” “Inflammation,” and “Tophus.” The publication period was limited to 2019-2024. Out of 745 articles found, 12 were selected based on inclusion criteria, which included experimental, observational, and case study reports. The results show that MSU crystals induce inflammation through the infiltration of inflammatory cells such as neutrophils and macrophages. In chronic Gout, the formation of tophi, granulomatous lesions with a crystalline core, leads to bone and joint destruction. Understanding the histopathological aspects is crucial for more accurate diagnosis and more effective management of Gout arthritis. The progression of the disease is related to acute and chronic inflammation, as well as the destructive effects of tophi on joints and bones. In conclusion, MSU crystals play a significant role in triggering inflammation and tissue damage in Gout arthritis, and understanding histopathology can improve diagnostic accuracy and therapeutic efficacy.
AN EDUCATIONAL GAME APPLICATION TO ASSIST THE COMMUNITY IN REMEMBERING ROAD DIRECTIONS AND PLACES IN PALEMBANG Angelia, Nadya; Jannah, Miftahul; Valentino, Albert Amadeus; Liu, Michelle; Ibrahim, Ali
Jurnal Riset Informatika Vol. 4 No. 1 (2021): December 2021
Publisher : Kresnamedia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1283.31 KB) | DOI: 10.34288/jri.v4i1.138

Abstract

Visuospatial processing is one of the important aspects of everyday life, whether it is to travel or to recognize the location of objects around. Visuospatial processing can be improved in various way, one of which is by using repetition. WorldVenture app was created to help its users improve their visuospatial capability by remembering landmarks in the city where they live. WorldVenture was created using flutter framework with five steps, namely literature study, data and information collection, application designing, testing, and evaluation. This app will have three main features: Flashcard, Quiz, and Notes. WorldVenture testing result, using questionnaires, showed 64,5% people out of 30 respondents rated WorldVenture excellent for improving visuospatial capabilities and as many as 35.5% of respondents rated it good.
Co-Authors Ali Ibrahim Angelia, Nadya Diba, Msy. Farah Larasati, Veny Liu, Michelle Miftahul Jannah Nita Parisa