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All Journal IDJP (Indonesian Journal of Pharmaceutics) Indonesian Journal of Biological Pharmacy
Afinasari, Auliya
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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Uji Efektivitas Ekstrak Turbinaria ornata Dalam Sediaan Hidrogel Dikombinasikan Dengan Human Epidermal Growth Factor (hEGF) Firdaus, Muhammad Fahd; Apriali, Kirka Dwi; Rahmawati, Adira; Afinasari, Auliya; Aulia, Safira; Zuhrotun, Ade
Indonesian Journal of Biological Pharmacy Vol 1, No 2 (2021): IJBP (Desember)
Publisher : Department of Biological Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (590.57 KB) | DOI: 10.24198/ijbp.v1i2.37398

Abstract

Luka bakar merupakan kondisi dimana suatu jaringan rusak atau hilang akibat kontak kulit dengan panas.Turbinaria ornata mengandung senyawa yang memiliki aktivitas sebagai penutup luka serta antimikroba yaitu Neophytadiene dan 4,8,12,16-Octadecatetraen-1-ol,4,9,13,17-tetramethyl. Dalam hidrogel ini diformulasikan ekstrak dengan kombinasi hEGF sebagai faktor pertumbuhan yang sangat berpotensi dalam proses penyembuhan luka.Tujuan dari riset ini yaitu memperluas pemanfaatan ekstrak T. ornata untuk pengobatan jenis luka lain yaitu luka bakar. Metode yang digunakan dalam penelitian ini adalah riset empirik. Dalam satu formula sediaan ini, terdapat ekstrak kental turbinaria dengan kadar 200mg/10ml. Penelitian ini menghasilkan sediaan hidrogel kombinasi ekstrak T. ornata  dengan hEGF yang baik karena homogen dan memiliki pH menyerupai pH kulit yaitu 6.
Nanoparticle Drug Delivery System Afinasari, Auliya; Amalia, Eri
Indonesian Journal of Pharmaceutics Vol 4, Issue 3, Sep - November, 2022
Publisher : Universitas Padjadjaran (Unpad)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/idjp.v4i3.44254

Abstract

Drug Delivery System is a method of drug formulation, which aims to deliver the active substance to achieve a therapeutic effect in the body. Along with the development of science in the field of drug manufacturing technology, drug delivery systems have evolved from conventional to targeted delivery systems and even nanorobots, gene therapy, biological products, and long-term delivery systems.Among the drug delivery systems that have been developed, nanotechnology has been applied as a targeted delivery system such as in cancer treatment. This review is focused on nanotechnology especially in nanoparticle dosage forms, including liposomes, dendrimers, niosomes, micelles, solid-lipid nanoparticles, nanospheres, nanocapsules, and gold nanoparticles. The data were collected from 41 primary published journals and 20 supporting literatures. The basic principles, strategies, and carrier systems used in the manufacture of each preparation will be presented in this article, including prospects in the future for SOPs.
Co-Authors Ade Zuhrotun Amalia, Eri Apriali, Kirka Dwi Aulia, Safira Firdaus, Muhammad Fahd Rahmawati, Adira