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All Journal Jurnal Biomedika dan Kesehatan Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Rachmawati Dwi Agustin
Brawijaya University
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Aktivitas Antibakteri Gel Hand SanitizerMinyak Biji Pala (MyristicafragransHoutt) Terhadap Bakteri Gram Positif dan Gram Negatif Agustin, Rachmawati Dwi; Taihuttu, Yuniasih Mulyani Jubeliene
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 11 No. 2 (2024): October
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v11i2.4285

Abstract

One of the media for spreading the bacteria the fastest in hand, so an antibacterial substance is needed. Hand sanitizers, which are more effective in killing bacteria, by quickly processing hands with airflow. However, most of the hand sanitizers' content is alcohol, which can repeatedly irritate the skin, so natural ingredients are needed to make hand sanitizers. Nutmeg is a tropical plant that is commonly found in Indonesia. Nutmeg contains active compounds as antibacterial agents. Research on the antibacterial activity test of the hand sanitizer gel formulation of nutmeg oil has been carried out. This study aimed to determine the antibacterial activity in the optimum formulation of the nutmeg oil hand sanitizer gel. Antibacterial activity test using the disc diffusion method showed that the nutmeg oil hand sanitizer gel had antibacterial activity against several pathogenic bacteria, including Escherichia coli, Staphylococcus aureus, Propionibacterium acne, and Pseudomonas aeruginosa, which were optimum concentration in nutmeg oil by 15% (F1), obtained the inhibition power of 1.42 mm; 1.35 mm; 0.56 mm; and 1.67 mm, respectively.
Analisis Aterogenik Indeks Plasma Terhadap Obesitas dan Normal Weight Obesity Pada Dewasa Muda Anwar, Rofila Asjad; de Lima, Filda Vionita Irene; Latief, Rahmi Rifany; Mus, Rosdiana; Latuconsina, Vina Zakiah; Agustin, Rachmawati Dwi
Jurnal Biomedika dan Kesehatan Vol 8 No 3 (2025)
Publisher : Fakultas Kedokteran Universitas Trisakti

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Abstract

Background Obesity is characterized by the excessive accumulation of body fat, which heightens cardiovascular risk. Normal Weight Obesity (NWO) is a recently identified phenotype of obesity. It describes individuals who have a Body Mass Index (BMI) within the normal range but a high body fat percentage (>25% for male and >30% for female). Despite its outwardly healthy appearance, NWO poses significant hidden cardiovascular risks due to this internal fat accumulation. A major biomarker for determining cardiovascular risk is the Atherogenic Indeks of Plasma (AIP), which is calculated as the logarithmic value of the ratio of triglycerides to high-density lipoprotein (HDL) cholesterol. Methods This study utilized a total sample size of 52 subjects, which were divided into two equal groups 26 students comprised the Normal Weight Obesity (NWO) group and 26 students comprised the obesity group. The classification of participants into the NWO and obesity groups was determined through measurements obtained using a Bioelectrical Impedance Analyzer (BIA) and microtoise. Measurements of triglyceride and High-Density Lipoprotein (HDL) levels were conducted using the Glycerol Phosphate Oxidase/Peroxidase (GPOP) method and the Cholesterol HDL Direct method, respectively, at the Maluku Province Health Laboratory. The resulting data were subjected to statistical analysis using the Chi-square test. Results There were no significant difference in AIP value (p value = 0.578) between NWO group (Mean=0.19; SD=0.18) and obesity group (Mean=0.26; SD=0.23). Conclusions This study concluded that there was no difference in the AIP value of the NWO and obesity groups in medical students of the Faculty of Medicine, Pattimura University. Keywords: Atherogenic Index Plasma; Normal Weight Obesity; Obesity
Co-Authors Anwar, Rofila Asjad de Lima, Filda Vionita Irene Latief, Rahmi Rifany Latuconsina, Vina Zakiah Mus, Rosdiana Taihuttu, Yuniasih Mulyani Jubeliene