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Juwita Endrawati, Komang
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Health Professions Medicine & Pharmacology Public Health

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Respons Sistem Imun pada Epilepsi Juwita Endrawati, Komang
Cermin Dunia Kedokteran Vol 45, No 11 (2018): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (723.697 KB) | DOI: 10.55175/cdk.v45i11.561

Abstract

Epilepsi merupakan kondisi kronis dengan penyebab multifaktorial. Jumlah pasien resisten obat sekitar 20-40% diduga akibat keterlibatan peran imun dalam epileptogenesis. Beberapa komponen imunitas neuron berperan pada patogenesis epilepsi dan penggunaan obat anti epilepsi berpengaruh pada sistem imun. Obat anti epilepsi bersifat imunosupresan; imunitas innate dan adaptif berubah bermakna saat dan setelah kejang.Epilepsy is a chronic condition with multifactorial causes. Aproximately 20-40% patients are drug resistant thought to be due to role of immunity in epileptogenesis. Some components of immunity in neurons play a role in the pathogenesis of epilepsy. Anti-epilepsy drugs are immunosuppressive; innate; adaptive immunity changes significantly during and after seizures.
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