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All Journal Cermin Dunia Kedokteran Indonesian Health Journal Bali Dermatology Venereology and Aesthetic Journal Cermin Dunia Kedokteran
Saraswati, Putu Dyah Ayu
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Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Peran dan Fungsi Pelembap pada Tatalaksana Dermatitis Atopi Martalova AJ, Adelia; Saraswati, Putu Dyah Ayu
Cermin Dunia Kedokteran Vol 47, No 2 (2020): Penyakit Infeksi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (698.492 KB) | DOI: 10.55175/cdk.v47i2.367

Abstract

Dermatitis atopi merupakan inflamasi kulit yang sering terjadi pada berbagai kelompok usia. Defek fungsi barier kulit, genetik, disregulasi sistem imun, dan lingkungan saling berinteraksi sebagai faktor penyebab. Manajemen meliputi perawatan kulit optimal, salah satunya dengan penggunaan rutin pelembap. Makalah ini akan memaparkan peran dan fungsi pelembap dalam dermatitis atopi.Atopic dermatitis is a common skin inflammation in any age group. Many factors, such as skin barrier function defect, genetic, immune system dysregulation, and environment, are related as contributing factors. Management includes optimal skin care, including routine moisturizer use. This article discuss the moisturizer’s role in atopic dermatitis.
Peran dan Fungsi Pelembap pada Tatalaksana Dermatitis Atopi Martalova AJ, Adelia; Saraswati, Putu Dyah Ayu
Cermin Dunia Kedokteran Vol 47, No 3 (2020): Dermatologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (698.492 KB) | DOI: 10.55175/cdk.v47i3.368

Abstract

Dermatitis atopi merupakan inflamasi kulit yang sering terjadi pada berbagai kelompok usia. Defek fungsi barier kulit, genetik, disregulasi sistem imun, dan lingkungan saling berinteraksi sebagai faktor penyebab. Manajemen meliputi perawatan kulit optimal, salah satunya dengan penggunaan rutin pelembap. Makalah ini akan memaparkan peran dan fungsi pelembap dalam dermatitis atopi.Atopic dermatitis is a common skin inflammation in any age group. Many factors, such as skin barrier function defect, genetic, immune system dysregulation, and environment, are related as contributing factors. Management includes optimal skin care, including routine moisturizer use. This article discuss the moisturizer’s role in atopic dermatitis.
Adult-onset Henoch-Schonlein purpura: A case report Ruslan, Lettisia Amanda; Saraswati, Putu Dyah Ayu
Bali Dermatology Venereology and Aesthetic Journal BDVAJ - Volume 7, Issue 2 (July 2024)
Publisher : Explorer Front

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/balidervenaesthj.v7i2.99

Abstract

Background: Henoch-Schönlein purpura (HSP) is a cutaneous small vessel vasculitis that typically affects children under ten but may also occur in adults. This study aims to report a rare instance of an adult patient with HSP to expand our knowledge and prevent delayed diagnosis and treatment. Case: A 21-year-old female patient presented with palpable purpuric lesions on the lower abdomen, buttocks, and lower limbs. In addition, the patient complained of abdominal pain and joint pain. The patient had suffered an upper respiratory tract infection with spontaneous resolution three days before the skin lesions. Laboratory tests showed leukocytosis and elevated anti-Streptolysin O titer. The patient was diagnosed with HSP and given oral methylprednisolone, antibiotics, and symptomatic treatment. She showed clinical improvement after taking medication. Conclusion: Henoch-Schönlein purpura is typically a self-limiting disease and infrequent in adults, but it has the potential to manifest into life-threatening conditions such as end-stage renal failure. An integrated multidisciplinary approach is needed for early diagnosis and management.  
Disseminated Herpes Zoster Subsequent to Ocular Shingles in an Immunocompetent Young Man Following Facial Trauma: A Case Report Grady, Grady; Rahayu, Dewa Ayu Putu Mitha Paramitha; Saraswati, Putu Dyah Ayu
Indonesian Health Journal Vol. 4 No. 2 (2025): Indonesian Health Journal
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/ihj.v4i2.726

Abstract

Herpes zoster (HZ) results from the reactivation of latent varicella-zoster virus (VZV), typically triggered by aging or immunosuppression. Herpes zoster ophthalmicus (HZO) affects the ophthalmic branch of the trigeminal nerve (V1), posing a risk of ocular complications. Disseminated herpes zoster (DHZ), a rare form of HZ, is defined by ?20 vesicular lesions beyond the primary and adjacent dermatomes, potentially leading to systemic complications and increased morbidity. Case Presentation: A 36-year-old immunocompetent male presented with disseminated vesicular eruptions across the body, sparing the knees and lower legs, four days after the initial appearance of vesicles along the left ophthalmic (V1) branch of the trigeminal nerve. Notably, the patient had a history of minor trauma at the same site one week prior. A comprehensive evaluation and multidisciplinary management were undertaken, involving ophthalmologists, dermatologists, and neurologists. By the third day of treatment, his pain had significantly subsided, no new lesions had developed, and was discharged. Conclusion: DHZ can occur in immunocompetent individuals at any age, but is more common in older patients. A meticulous history and physical examination are essential, as dermatomal herpes zoster may progress to dissemination. Additionally, the potential link between recent trauma and zoster reactivation may play a contributory role, highlighting the importance of early recognition for prompt intervention.
Tato dan Risiko Komplikasinya Putri, Putu Ayu Krisna Cahyaning; Saraswati, Putu Dyah Ayu
Cermin Dunia Kedokteran Vol 52 No 8 (2025): Agustus 2025
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i8.1584

Abstract

Tattoos are a form of body modification that involves inserting indelible ink into the dermis to alter skin pigmentation. Based on the duration of pigment retention, tattoos are classified into two types: temporary tattoos and permanent tattoos. The increase in the prevalence of tattooing has raised awareness of the adverse reactions associated with tattoos, which are not limited to the risk of dermatological complications, but also systemic complications. Adverse reactions related to tattoos are classified into infection, inflammatory, and neoplastic complications. Risks of infection and neoplasia are only observed in permanent tattoos. Hypersensitivity reactions to tattoo pigments are the most common adverse effects for both permanent and temporary tattoos. Risk of infection during permanent tattooing varies based on the causative pathogens, which may include bacterial, viral, fungal, and parasitic infections, manifesting as both localized and systemic issues. Adverse reactions have also been reported in relation to the pigment colors used in tattoos, suggesting that certain pigment components may be associated with harmful effects. A standardized regulatory framework is necessary to ensure the safety of tattoo inks and to prevent adverse health outcomes.
Penyakit Bulosa Autoimun pada Lanjut Usia: Tinjauan Pustaka Putra, Gilang Widratama; Saraswati, Putu Dyah Ayu
Cermin Dunia Kedokteran Vol 52 No 11 (2025): November 2025
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v52i11.1572

Abstract

The increase in cases of bullous diseases in the elderly is related to various factors. Aging causes a decline in skin structure and integrity, making it more susceptible to bullous diseases. This disease occurs because the aging process causes immune system dysregulation, which increases the risk of autoimmune conditions. Bullous diseases that commonly occur in the elderly are usually bullous pemphigoid (an autoimmune bullous condition) and pemphigus vulgaris (a skin disease that causes blisters), which are associated with significant morbidity and mortality. Bullous pemphigoid is characterized by tense subepidermal blisters, while pemphigus vulgaris is characterized by loose suprabasal blisters that rupture easily. Histopathological examination and direct immunofluorescence are the gold standard for diagnosis. The management of autoimmune bullous diseases in the elderly is generally the same as for bullous diseases in general, such as corticosteroids and immunosuppressive agents. However, appropriate and effective management is necessary, along with increased attention to the risks of polypharmacy and drug side effects that may cause new problems in elderly patients, including an increased risk of infection, osteoporosis, and metabolic complications.
Tata Laksana Vaskulitis Kulit: Tinjauan Pustaka Devina, Wilona; Saraswati, Putu Dyah Ayu
Cermin Dunia Kedokteran Vol 53 No 03 (2026): Maret 2026
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v53i03.1591

Abstract

Cutaneous vasculitis represents a heterogeneous group of inflammatory disorders characterized by inflammation of the cutaneous blood vessel walls and surrounding perivascular tissue, with highly variable clinical manifestations depending on the size and anatomical location of the affected vessels. This condition may present as a disease limited to the skin or as part of a systemic disorder. Epidemiologically, cutaneous vasculitis can occur at all ages but is more frequently observed in adults, whereas in children it is generally self-limiting, with IgA vasculitis being the most common subtype. The etiology of cutaneous vasculitis is predominantly idiopathic; however, infections, medications, autoimmune diseases, and malignancies may also contribute. The pathogenesis involves immune complex deposition and mechanisms mediated by anti-neutrophil cytoplasmic antibodies (ANCA), leading to endothelial injury and vascular inflammation. The main clinical manifestation is palpable purpura, typically distributed symmetrically on the lower extremities, accompanied by various additional skin lesions such as papules, nodules, vesicles, and ulcers. Diagnosis is established through skin biopsy, which remains the gold standard, including histopathological examination and direct immunofluorescence. Most cases are mild and resolve spontaneously; however, systemic therapy is required in severe, chronic, or recurrent conditions. Overall, the prognosis of cutaneous vasculitis is favorable, with a low risk of progression to systemic vasculitis when appropriate diagnosis and management are implemented.
Co-Authors Devina, Wilona Grady, Grady Martalova AJ, Adelia Putra, Gilang Widratama Putri, Putu Ayu Krisna Cahyaning Rahayu, Dewa Ayu Putu Mitha Paramitha Ruslan, Lettisia Amanda