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All Journal Majalah Kesehatan FKUB Jurnal Penelitian Pendidikan IPA (JPPIPA) Cermin Dunia Kedokteran Indonesian Andrology and Biomedical Journal
Gonius, Andry
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Education Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Physics Public Health

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The Role of Vitamin D in Enhancing Immunity and Its Recommendations Nagara, Adianto Jaya; Gonius, Andry
Cermin Dunia Kedokteran Vol 48, No 2 (2021): Farmakologi - Vitamin D
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (219.416 KB) | DOI: 10.55175/cdk.v48i2.1304

Abstract

Vitamin D is a fat-soluble vitamin with a very important role in regulating the body's calcium balance. It also plays an important role in cell growth, even optimizing the immune system. American Academy of Dermatology recommends supplementation of oral vitamin D to meet daily vitamin D requirements.Vitamin D adalah vitamin larut dalam lemak yang penting untuk mengatur kadar kalsium tubuh, juga berperan dalam pertumbuhan sel dan sistem imun. Untuk memenuhi kebutuhan vitamin D dalam tubuh, American Academy of Dermatology menganjurkan suplementasi oral vitamin D. 
KORELASI PROFIL HEMATOLOGI DAN TROMBOPOIETIN DENGAN TERJADINYA PERDARAHAN PADA PASIEN SIROSIS HEPATIS Firani, Novi Khila; Fatonah, Siti; Wardhani, Shinta Oktya; Supriono; Gonius, Andry; Mustofa Aidid
Majalah Kesehatan Vol. 11 No. 3 (2024): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/majalahkesehatan.2024.011.03.2

Abstract

Sirosis hepatis adalah penyakit kronis hati yang ditandai adanya fibrosis hati yang dapat menyebabkan abnormalitas fungsi hati baik pada metabolisme maupun sintesis faktor koagulasi. Perdarahan akut saluran cerna atas merupakan akibat hipertensi portal dan kegagalan fungsi hati memproduksi faktor pembekuan darah pada sirosis hepatis. Belum diketahui bagaimana korelasi parameter hematologi dan trombopoietin dengan terjadinya perdarahan pasien sirosis hepatis. Tujuan penelitian ini untuk mengetahui korelasi kadar hemoglobin, leukosit, trombosit dan trombopoietin dengan terjadinya perdarahan pada pasien dengan sirosis hepatis. Desain studi ini adalah observasional analitik pada pasien sirosis hepatis yang dirawat di RSUD dr. Saiful Anwar Malang, yang memenuhi kriteria inklusi dan eksklusi. Analisis statistik menggunakan uji komparasi dan uji korelasi Spearman. Hasil penelitian didapatkan sejumlah 35 orang pasien sirosis hepatis. Kadar trombopoietin yang lebih tinggi pada pasien sirosis yang mengalami perdarahan dibandingkan pasien sirosis tanpa perdarahan. Kadar hemoglobin lebih rendah pada pasien sirosis yang mengalami perdarahan dibandingkan yang tanpa perdarahan. Terdapat ko relasi yang bermakna antara kadar hemoglobin (r = -0,653; p < 0,05) dan kadar trombopoietin (r = 0,355; p < 0,05) dengan terjadinya perdarahan pasien sirosis hepatis. Tidak ada perbedaan yang signifikan kadar leukosit dan trombosit pada pasien sirosis yang mengalami perdarahan dan tanpa perdarahan. Dari penelitian ini dapat disimpulkan bahwa kondisi perdarahan pada pasien sirosis hepatis berkorelasi dengan penurunan kadar hemoglobin dan peningkatan kadar trombopoietin.
The Impact of a Web-Based Educational Initiative in Malang Regency: Enhancing Late Onset Hypogonadism (LOH) Awareness Through Community Service Irnandi, Dicky Faizal; Hanggara, Dian Sukma; Khotimah, Husnul; Rifqi, Mochamad Shalahudin; Evangelista, Bernike Azza; Gonius, Andry; Kusdijanto, Amanda Yuanita
Indonesian Andrology and Biomedical Journal Vol. 4 No. 2 (2023): December
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/iabj.v4i2.51414

Abstract

Late Onset Hypogonadism (LOH), commonly known as andropause, poses significant hormonal challenges for elderly men, impacting their overall quality of life. With testosterone levels naturally declining from the age of 30 and accelerating beyond 40, this hormonal imbalance can manifest in symptoms that degrade the well-being of men. This community service initiative aimed to improve understanding and early detection of LOH among the Indonesian male population. A web-based application, "Skrining Andropause" was developed, allowing individuals to self-assess their LOH risk through the validated Androgen Deficiency in the Aging Male (ADAM) questionnaire. The application included educational videos to enhance public awareness of andropause. Pre- and post-tests were conducted as success indicators, involving 40 male participants aged 40 and above in Malang Regency. Statistical analyses were performed to assess the impact on knowledge related to andropause across different educational backgrounds and age groups. Significant improvement in public understanding of andropause was observed (p=0.000). While educational backgrounds were not significantly associated with initial knowledge (p=0.100), nor with the increase in pre-to-post-test scores (p=0.100). When associating age groups with initial knowledge (p=0.308) and the increase in pre-to-post-test scores (p=0.308), results were not statistically significant. The observed substantial improvement in andropause understanding highlights the efficacy of our educational approach. Respondents, irrespective of educational background, shared a baseline understanding, with those with basic education showing the most significant improvement. Notably, the youngest age group displayed the highest baseline awareness. However, the oldest age group exhibited the least responsiveness to our educational media.
STUDI IMPEDANSI LISTRIK PADA DIABETES MELLITUS` Putri, Laily Ardhianti; Retnaningtyas, Ekowati; Kurniawan, Shahdevi Nandar; Susianti, Hani; Gonius, Andry; Sari, Atika Windra; Widodo, Chomsin Sulistya
Jurnal Penelitian Pendidikan IPA Vol 10 No 7 (2024): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i7.7043

Abstract

Diabetes mellitus has raised concerns about structural and functional changes in blood cells, as well as changes in blood impedance. The purpose of this study is to investigate the relationship between electrical impedance values measured with the Bioelectrical Impedance Analyzer (BIA) in diabetes patients. Blood samples were collected from 5 healthy people and 5 diabetes patients for the study. Electrical impedance testing with a BIA. The impedance method determines the electrical properties of blood by measuring its resistance and reactance at various frequencies. The results of the BIA are analyzed and compared to body health parameters such as the blood glucose level index. The average electrical impedance value in diabetes mellitus patients measured at a frequency of 100 Hz to 100 kHz with a current injection of 10 μA was found to be lower than the average electrical impedance value in healthy people. This study shows that the electrical impedance value of diabetes mellitus patients is lower than the impedance value of healthy people. This is consistent with diabetes mellitus patients' blood glucose levels, which are higher than healthy people's blood glucose levels.
Co-Authors Chomsin Sulistya Widodo Dicky Faizal Irnandi Ekowati Retnaningtyas Evangelista, Bernike Azza Hanggara, Dian Sukma Hani Susianti Heni Pujiastuti Kusdijanto, Amanda Yuanita Mustofa Aidid Nagara, Adianto Jaya Novi Khila Firani Putri, Laily Ardhianti Rifqi, Mochamad Shalahudin Sari, Atika Windra Shahdevi Nandar Kurniawan, Shahdevi Nandar Shinta Oktya Wardhani, Shinta Oktya Siti Fatonah Supriono