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All Journal Biology, Medicine, & Natural Product Chemistry Indonesian Journal of Chemistry Aplikasia: Jurnal Aplikasi Ilmu-Ilmu Agama Kaunia: Integration and Interconnection of Islam and Science Journal Bulletin of Chemical Reaction Engineering & Catalysis
Widiakongko, Priyagung Dhemi
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Religion Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Other

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PARTISIPASI MASYARAKAT DALAM PEMBUATAN RUMAH KACA (GREEN HOUSE) SEBAGAI SARANA PEMBENIHAN BERWAWASAN EKOEDUWISATA DI KEBUN BUAH BENDOSARI Widiakongko, Priyagung Dhemi
Aplikasia: Jurnal Aplikasi Ilmu-ilmu Agama Vol. 23 No. 2 (2023):
Publisher : UIN Sunan Kalijaga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/aplikasia.v23i2.3220

Abstract

The construction of a greenhouse as a nursery facility with an ecotourism perspective has been carried out at the Bendosari Orchard, Sumbersari Moyudan, Sleman. The purpose of making this greenhouse is as a means of seeding fruit plants which are a source of income for the Bendosari Orchard, namely guava and avocado and as a tourist attraction to attract more visits to the fruit garden. This research was carried out using the Rural Rapid Appraisal (RRA) approach with 6 stages, namely socialization, interviews, workshops on equalizing perceptions about fruit plant breeding using the grafting method and about greenhouses, surveys of prospective greenhouse construction locations, workshops on planning and building greenhouses and home supervision. glass. With this research, the perception and awareness of garden managers regarding fruit plant nurseries has increased as proven through questionnaires and the success of building a Greenhouse at the Bendosari Orchard. Apart from that, park managers have also realized the need to build greenhouses independently. The greenhouse that was built was made of galvalum, UV plastic and insect-proof glass. This is done to maintain ecological aspects in the greenhouse and in the Bendosari Orchard.
Preparation of Ni/Bentonite Acid-Activated using Dragon Fruit Peel Extract (Hylocereus polyrhizus) As a Reductor for One Pot Synthesis of Menthol Marhayuni, Yuni; Widiakongko, Priyagung Dhemi
Biology, Medicine, & Natural Product Chemistry Vol 13, No 2 (2024)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2024.132.523-530

Abstract

Ni/Bentonite is acid-activated has been synthesized using dragon fruit peel extract (Hylocereus polyrhizus) as a reductor through an impregnation method. This research aims to characterize Ni/Bentonite acid-activated using dragon fruit peel extract as a reductor based on FTIR and XRD instruments and to analyze the product obtained in one pot synthesis of menthol from citronellal using Ni/Bentonite acid-activated catalyst. Preparation of Ni/Bentonite acid-activated catalyst was carried out using a wet impregnation method with dragon fruit peel extract as a natural reductor. The successful synthesis of Ni/Bentonite acid-activated was confirmed by FTIR spectrum identification, showing absorptions at wavelengths of 1049.28 cm?¹ and 694.37 cm?¹, indicating Si-O groups in the bentonite, and XRD diffractogram indicating the presence of Ni at diffraction peaks of 2? = 40.5° and 2? = 47.74°. The catalyst was able to convert menthol by 0.77% through one pot synthesis without using H? sources such as potassium formate.
Development of Graphene Oxide-Based Antibacterial Agents via ZnO/Eugenol Modification: Experimental and Computational Analysis Triatmaja, Karisma; Kunarti, Eko Sri; Suyanta, Suyanta; Widiakongko, Priyagung Dhemi
Indonesian Journal of Chemistry Vol 25, No 2 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.97866

Abstract

The development of new antibacterial agents is proposed to solve the problem of drug-resistant bacterial strains caused by antibiotic misuse. The aim of this study was to improve the antibacterial activity by modifying graphene oxide (GO) using ZnO/eugenol and analyzing the interaction computationally. The study was started with GO synthesis using the modified Hummer method, followed by the dispersion of ZnO/eugenol through the mechanochemical method to GO to form GO/ZnO/eugenol composite. The composite was characterized using XRD, FTIR, UV-vis, SEM, and TEM. Results showed that the sonochemical method successfully prepared the GO/ZnO/eugenol composite. This material has better antibacterial E. coli activity than GO, with an inhibition zone of 11.5 mm in diameter, while pure GO showed no inhibition zone. MIC test presented that GO/ZnO/eugenol composite with 25 mg/mL suspension effectively prevented bacterial colony growth, while GO could only inhibit with 50 mg/mL suspension. Additionally, computational analysis through molecular docking suggested that the GO/ZnO/eugenol mechanism of action involves interference with DNA replication by hydrogenously interacting with the active site of DNA gyrase of E. coli bacteria. These findings highlight the potential of GO/ZnO/eugenol as a promising antibacterial agent for combating drug-resistant bacterial strains.
Molecular Docking Study of Eugenol and Its Derivatives as Potential Anti-Ischemia Agents for Angiotensin Converting Enzyme (ACE) Inhibition Prabawati, Susy Yunita; Triatmaja, Karisma; Widiakongko, Priyagung Dhemi
Indonesian Journal of Chemistry Vol 25, No 3 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.101791

Abstract

Mortality due to ischemic stroke has increased significantly, especially during the COVID-19 pandemic. Preventive measures are urgently needed to reduce the severity of ischemic stroke, which is mainly caused by blood vessel blockage due to increased secretion of angiotensin II (ANG II) by angiotensin-converting enzyme (ACE). This study investigated the potential of eugenol and its derivatives as ACE inhibitors using molecular docking, an in silico approach for drug discovery by using PLANTS software. The results showed that several eugenol derivatives, including (E)-1-(2-(4-allylphenoxy)acetyl)-4-cinnamoylthiosemicarbazide, exhibited potent ACE inhibition, with docking scores comparable to the native ligand (lisinopril) and superior to several commercial drugs. Physicochemical evaluation revealed that derivatives such as 5a, 5b, 7, and 9a had favorable molecular weight, total polar surface area, and lipophilicity (log P), thereby enhancing their permeability and bioavailability. Drug-likeness analysis confirmed that the compound meets several criteria, including Lipinski, Pfizer, and Golden Triangle rules, highlighting its potential safety and efficacy. Key binding interactions, including hydrogen bonds, hydrophobic interactions, and electrostatic interactions in the ACE active site, further support its candidacy as an ACE inhibitor. These findings suggest that eugenol derivatives are promising candidates for the development of therapies targeting ischemic stroke through ACE inhibition.
Synthesis of NiO/Zeolite Catalyst and Its Performance in Renewable Biomass Gasification Electric Generator Niyartama, Thaqibul Fikri; Widiakongko, Priyagung Dhemi
Kaunia: Integration and Interconnection Islam and Science Journal Vol. 21 No. 1 (2025)
Publisher : Fakultas Sains dan Teknologi UIN Sunan Kalijaga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/kaunia.5266

Abstract

Research on NiO/Zeolite catalytic biomass gasification to produce electricity has been completed. This study aims to study the effect of the NiO/Zeolite catalyst on the voltage and current generated in the gasification process. This research was carried out by making NiO/Zeolite catalysts using the wet impregnation method, followed by contructing a gasification device plus installing a batch of catalysts in the reactor, and then testing the electrical parameters produced by the gasification equipment. The results obtained are NiO/Zeolite catalysts which have been successfully synthesized using FTIR spectral indicators and XRD diffractograms with the appearance of NiO and Ni peaks at angles of 2θ 28o and 63o. The resulting catalyst was also reported to have succeeded in increasing voltage stability compared to the gasification process without a catalyst with a maximum value of 250 V and an average value of 225 V. The NiO/Zeolite catalyst also succeeded in increasing the current value and stabilizing the current value compared to the non-reaction gasification process with a maximum of 50 A and an average of 44 A.
Green Synthesis of ZnO Nanoparticles using Aloe Vera Extract and Xanthan Gum as Modifier for Photocatalytic Degradation of Anionic and Cationic Dye in Aqueous Solution Fajriati, Imelda; Widiakongko, Priyagung Dhemi; Krisdiyanto, Didik; Hermawati, Heti
Bulletin of Chemical Reaction Engineering & Catalysis 2025: Just Accepted Manuscript and Article In Press 2025
Publisher : Masyarakat Katalis Indonesia - Indonesian Catalyst Society (MKICS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9767/bcrec.20495

Abstract

This research employed a green synthesis approach to produce zinc oxide (ZnO) nanoparticles, using Aloe vera latex extract as both the natural reducing and stabilizing agent. To improve particle dispersion and suppress agglomeration, Xanthan gum was employed as a biopolymeric modifier. The ZnO nanoparticles were synthesized under ambient conditions without the need for surfactants or hazardous chemicals. Characterization through FTIR, XRD, SEM, TEM, and UV–Vis diffuse reflectance spectroscopy demonstrated that the synthesized ZnO nanoparticles were highly crystalline and adopted a hexagonal wurtzite structure. The incorporation of xanthan gum significantly reduced the crystallite size, enhanced surface homogeneity, and increased the optical band gap energy from 3.19 eV to 3.39 eV. Photocatalytic activity was evaluated using Remazol Yellow (anionic dye) and Rhodamine B (cationic dye) under UV light irradiation. The ZnO-AL/XG nanocomposite exhibited superior photocatalytic performance compared to ZnO synthesized without xanthan gum. This enhanced activity was attributed to improved nanoparticle dispersion, reduced recombination rates of photogenerated charge carriers, and better surface interaction with dye molecules. From the recycling study of ZnO-AL/Xg and ZnO-AL, it has been observed that the photocatalyst is still able to remove the color of the RY and RB solution up to 3 times of use with results above 50% of photodegradation percentage. The findings highlight the potential of Aloe vera–xanthan gum–based synthesis as a sustainable and efficient strategy for producing ZnO nanomaterials applicable in wastewater treatment.
Co-Authors Didik Krisdiyanto Eko Sri Kunarti Hermawati, Heti Imelda Fajriati Marhayuni, Yuni Susy Yunita Prabawati Suyanta Suyanta Thaqibul Fikri Niyartama Triatmaja, Karisma