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Nur Rahmi Amma
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EFEK HIPOGLIKEMIK EKSTRAK DAUN MURBEI (MORUS MULTICAULIS) TERHADAP KADAR GLUKOSA DARAH TIKUS DIABETES MELITUS Amma, Nur Rahmi
Sainstek Vol 6, No 1, 2011
Publisher : Jurnal Sainstek

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Abstract

Diabetes mellitus is one of the health problem in community. The research was aimed to analysis the hypoglycemic effect of extract Mullberry leaves in blood glucose levels diabetic rats. Completely Randomized Design was used in this research. 45 rats Sprague dawley aged 70 days were administered alloxan by intraperitonial (125 mg/kg body weight) to induced diabetes. Treatment randomly assigned to: (MKA) an extract water provided by ripe mulberry dry leaves, (MSA) an extract water provided by green mulberry fresh leaves, (MSL) an extract hexane provided by green mulberry fresh leaves, (TSA) an extract water provided by green mulberry fresh leaves, (TSL) an extract hexane provided by ripe mulberry fresh leaves, (MKL) an extract hexane provided by ripe mulberry dry leaves,(TKL) an extract hexane provided by ripe mulberry dry leaves), (TKA) an extract water provided by ripe mulberry dry leaves, and control without extract. Effect of extracts from nine treatment on blood glucose levels of diabetic rats was determined at various time interval for 1,3,5 hour after oral administration of the extract at 0,01 mg dose /g body weight rat. The results showed that the glucose levels of diabetic rats treated with extract mulberry leaves significantly decrease, respectly, at 1hour , 3 hours and 5 hours administration (p
PENGARUH PEMBERIAN GARAM SODIUM RENDAH TERHADAP PENURUNAN TEKANAN DARAH PENDERITA HIPERTENSI RAWAT JALAN DI BLUD RUMAH SAKIT UMUM PROF.DR.H. ALOE SABOE GORONTALO ., Salman; Talibo, Sofyawati; Amma, Nur Rahmi
Sainstek VOL 07, NO 02, 2013
Publisher : Sainstek

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Tujuan penelitian : Mengetahui pengaruh pemberian garam sodium rendah terhadap penurunan tekanan darah penderita hipertensi rawat jalan di BLUD Rumah Sakit Umum Prof. Dr. H. Aloe Saboe Gorontalo. Metode penelitian : Jenis penelitian yaitu quasi eksperimen dengan rancangan Pre and post test control group design. Subjek penelitian yaitu pasien hipertensi rawat jalan. Subjek dibagi dalam 2 kelompok, yaitu kelompok intervensi (perlakuan) dan kelompok kontrol (tanpa perlakuan). Analisa data menggunakan komputer dengan program SPSS. Analisis perbedaan mean tekanan darah sebelum dan sesudah intervensi dari masing-masing kelompok menggunakan t-test. Hasil penelitian menunjukkan karakteristik responden; umur: frekuensi terbanyak kelompok umur 55-60 tahun (49,0%); jenis kelamin terbanyak perempuan (62,5%); status/jenis pekerjaan terbanyak ibu rumah tangga/tidak bekerja (41,3%); tingkat pendidkan terbanyak tamat SLTP (45,2%). Gambaran pengaruh pemberian garam sodium rendah pada penderita hipertensi; Rata-rata penurunan tekanan darah: kelompok intervensi; sistolik 14,62 mmHg, diastolik 7,50 mmHg. Kelompok kontrol ; sistolik 5,19 mmHg dan diastolik 6,35 mmHg. Uji t pada 0,01; terdapat perbedaan signifikan rata-rata penurunan tekanan darah sistolik antara kelompok intervensi dengan kelompok kontrol (p value < 0,01) dan tidak terdapat perbedaan signifikan rata-rata penurunan tekanan darah diastolik antara kelompok intervensi dengan kelompok kontrol (p value > 0,01). Kesimpulan pemberiam garam sodium rendah berpengaruh nyata terhadap penurunan tekanan darah sistolik penderita hipertensi dan tidak berpengaruh nyata terhadap penurunan tekanan darah diastolik penderita hipertensi.
Co-Authors Salman . Sofyawati Talibo