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All Journal PROSIDING SEMINAR NASIONAL de Fermat : Jurnal Pendidikan Matematika Abdimas Universal Jurnal Ilmu Kesehatan Bhakti Setya Medika Community Service Seminar and Community Engagement (COSECANT) Indonesian Journal of Jamu
Nur Ismiyati
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Health Professions Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Social Sciences Other

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Journal : PROSIDING SEMINAR NASIONAL

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AKTIVITAS SITOTOKSIK EKSTRAK ETANOLIK DAN FRAKSI DARI EKSTRAK ETANOLIK DAUN PANDAN (Pandanus amaryllifolius ROXB) TERHADAP SEL KANKER PAYUDARA MCF-7 Nur Ismiyati; Ana Mardiyaningsing; Trilestari -
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2015: Prosiding Bidang MIPA dan Kesehatan The 2nd University Research Colloquium
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Breast cancer is the second leading cause of cancer death among women in the world. To overcome the high incidence of cancer, the discovery and development of cancer treatments continues to be pursued. Pandan leaf (Pandanus amaryllifolius Roxb) is one of natural product that had cytotoxic activity. This study investigated the cytotoxic activity on MCF-7 breast cancer cells and to identify the chemical subtance groups of pandan leaves ethanol extract and fractions as chemopreventive agent. Active contents of pandan leaves was extracted by remaceration with 70% ethanol. Variation solvent of the water, chloroform, and ethyl acetate used to fractionation of pandan leaf ethanolic extract. Qualitative test were done to identify the chemical substances of pandan leaves etanolic extracts and fractions. Cytotoxic activity of sample was measured using MTT assay. The result of the phytochemical screening showed that the etanolic extract and water fractions of pandan leaf contained alcaloids, poliphenol and saponin. Chloroform fractions contained alcaloids and poliphenol. Pandan leaves ethanol extracts and chloroform fractions showed cytotoxic activity on MCF-7 cell line with IC50 of 540 μg/ml and 160 μg/ml whereas ethyl acetate fractions and water fractions of pandan leaves showed no cytotoxic activity on MCF-7 cell line.Keywords: Pandanus amaryllifolius Roxb, MCF-7 cell line, cytotoxic activity, etanolic extract,fractionation
ANALISIS PENGARUH PROGRAM KEWIRAUSAHAAN BERBASIS IPTEKS TERHADAP KESIAPAN BERWIRAUSAHA PADA MAHASISWA DI POLTEKKES BHAKTI SETYA INDONESIA Ana Mardiyaningsih; Nur Ismiyati; Rina Widiastuti
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2015: Prosiding Bidang Sosial Ekonomi dan Psikologi The 2nd University Research Colloquium
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Graduates students mostly oriented into a job seeker, not the job creators. There is an assumption that the preparations become entrepreneurs during college, lead to failure in passing study on university. Science and technology-based entrepreneurship education can change those assumption, so it can affect a student's readiness for entrepreneurship on 3 aspect: affective (attitude), cognitive (knowledge), and psychomotor (skills). This research aimed to analyzed the effect of science and technology-based entrepreneurship programs to changes in student readiness.This research was quasy experimental by intervented 20 tenants, the participant of Ipteks bagi Kewirausahaan (Science and Technology for Entrepreneurship) at the Polytechnic of Health Bhakti Setya Indonesia. Students attended a series of science and technology-basedentrepreneurship education program especially by approaching of herbal saintification in various kinds of products that lead to supporting therapy. The intervention consist of a motivational training program, training on creating products, internships in industry partners, and comparative study. Data was collected by questionnaire test in pre and post treatment to determine the student’s readiness changing. Data was analyzed by paired T-test. The result showed that the intervention of science and technology-based entrepreneurship programs can improve student’s readiness in entrepreneurship.Keywords: entrepreneurship, entrepreneurship readiness, student, science and technology
Co-Authors Alwhan Nurrochman Ana Mardiyaningsih Ana Mardiyaningsih Ana Mardiyaningsing Hendra Rohman Hery Setiyawan Husnul Khotimah Iramie Duma Kencana Irianto Permatasari, Besse Intan Pramita Yuli Pratiwi Rangga Pramudya Saputra Rina Widiastuti Sherly Herdianti Tri Lestari Trilestari -