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All Journal PROSIDING SEMINAR NASIONAL Pharmaciana: Jurnal Kefarmasian Journal of Fundamental and Applied Pharmaceutical Science JURNAL JAMU KUSUMA Indonesian Journal of Jamu
Ana Mardiyaningsih
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Education Health Professions Immunology & microbiology Medicine & Pharmacology

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ANALISIS PENGARUH PROGRAM KEWIRAUSAHAAN BERBASIS IPTEKS TERHADAP KESIAPAN BERWIRAUSAHA PADA MAHASISWA DI POLTEKKES BHAKTI SETYA INDONESIA Ana Mardiyaningsih; Nur Ismiyati; Rina Widiastuti
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2015: Prosiding Bidang Sosial Ekonomi dan Psikologi The 2nd University Research Colloquium
Publisher : Universitas Muhammadiyah Semarang

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Abstract

Graduates students mostly oriented into a job seeker, not the job creators. There is an assumption that the preparations become entrepreneurs during college, lead to failure in passing study on university. Science and technology-based entrepreneurship education can change those assumption, so it can affect a student's readiness for entrepreneurship on 3 aspect: affective (attitude), cognitive (knowledge), and psychomotor (skills). This research aimed to analyzed the effect of science and technology-based entrepreneurship programs to changes in student readiness.This research was quasy experimental by intervented 20 tenants, the participant of Ipteks bagi Kewirausahaan (Science and Technology for Entrepreneurship) at the Polytechnic of Health Bhakti Setya Indonesia. Students attended a series of science and technology-basedentrepreneurship education program especially by approaching of herbal saintification in various kinds of products that lead to supporting therapy. The intervention consist of a motivational training program, training on creating products, internships in industry partners, and comparative study. Data was collected by questionnaire test in pre and post treatment to determine the student’s readiness changing. Data was analyzed by paired T-test. The result showed that the intervention of science and technology-based entrepreneurship programs can improve student’s readiness in entrepreneurship.Keywords: entrepreneurship, entrepreneurship readiness, student, science and technology
PENGEMBANGAN POTENSI EKSTRAK DAUN PANDAN (Pandanus amaryllifolius Roxb) SEBAGAI AGEN ANTIBAKTERI Ana Mardiyaningsih; Resmi Aini
Pharmaciana Vol 4, No 2 (2014): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (140.377 KB) | DOI: 10.12928/pharmaciana.v4i2.1577

Abstract

Pandanus amayllifolius Roxb which commonly used as a flavoring and food coloring waspotentially have antibacterial activity. It should be an effort to develop a safe naturalpreservatives to reduce cases of food poisoning (foodborne disease) which mainly caused bybacterial pathogens. This study aims to determine the antibacterial potency of the water extract,ethanol, ethyl acetate, and a mixture of ethanol-ethyl acetate (1:1 v/v) extract againstStaphylococcus aureus and Escherichia coli based on the value of MIC (Minimum InhibitoryConcentration) and MBC (Minimum Batericidal Activity). The antibacterial activity wasevaluated by the Kirby-Bauer diffusion method by making the extract concentration of 25 and50 %, as well as the loading dose tested was 2.5 mg and 5 mg/disc. MIC and MBC wasevaluated by solid dilution method. The results showed that the ethanol extract and water extractdon’t have antibacterial activity against Staphylococcus aureus and Escherichia coli, whereasthe ethyl acetate extract and a mixture of ethanol-ethyl acetate (1:1 v/v) have an antibacterialactivity. Ethyl acetate extract showed the highest inhibitory potency. The MIC and MBC was 186 Pharmaҫiana, Vol. 4, No. 2, 2014: 185-192obtained at a level of 1.1% w/v and 6.7% w/v against Staphylococcus aureus, and 0.5% w/v and4.5% w/v against Escherichia coli.
UJI AKTIVITAS EKSTRAK ETANOL DAUN PEPAYA (Carica papaya) TERHADAP WAKTU KEMATIAN CACING Ascaridia galli Schrank SECARA IN VITRO Rina Widiastuti; Ana Mardiyaningsih; Yunisa Djayanti Putri
PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2015: Prosiding Bidang MIPA dan Kesehatan The 2nd University Research Colloquium
Publisher : Universitas Muhammadiyah Semarang

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Abstract

The prevalence of intestinal worms in Indonesia is still very high. Worming treatment can be performed using traditional medicine like papaya (Carica papaya). The purpose of this study to determine whether the ethanol extract of papaya (Carica papaya) concentration of 5% w / v, 10% w / v, 15% w / v has an influence on the time of death Ascaridia galli Schrank in vitro, knowing LC50 and LC90 , and knowing the chemical constituents in the ethanol extract of papaya (Carica papaya). Type of research is experimental because the use of treatment with the study design Posttest Only Control Groups Design. The sample used is Ascaridia galli Schrank females taken from chicken intestine. How it works in this research Ascaridia galli Schrank soak in a solution of NaCl 0.9% as negative control, a solution of piperazine citrate 0.9% as positive control, and a solution of ethanol extract of papaya (Carica papaya) with various concentrations. Each treatment group consisted of 15 worms were divided into five pots. Observations were made every 4 hours for 48 hours. Data were analyzed with the time of death worm SPSS 17 Kruskal Wallis method. Calculation LC50 and LC90 were analyzed by linear regression. Results of processing by Kruskal Wallis showed the ethanol extract of papaya (Carica papaya) concentration of 5% w / v, 10% w / v, and 15% w / v has an influence on the time of death Ascaridia galli Schrank in vitro. The results of calculations based on linear regression analysis showed LC50 ethanol extract of papaya (Carica papaya) at a concentration of 4.42% and LC90 at a concentration of 7.68%. Chemical identification results showed that ethanol extracts of leaves of papaya (Carica papaya) contain alkaloids, saponins, and tannins.Keywords: Carica papaya, Ascaridia galli Schrank.
STUDI TINGKAT PENGETAHUAN DAN POLA PENGGUNAAN OBAT TRADISIONAL SEBAGAI TERAPI KOMPLEMENTER PENYAKIT DEGENERATIF DI KAUMAN NGANJUK Iramie Duma Kencana Irianto; Vertika Susandy; Ana Mardiyaningsih
Jurnal Jamu Kusuma Vol. 2 No. 2 (2022): JURNAL JAMU KUSUMA
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (341.575 KB) | DOI: 10.37341/jurnaljamukusuma.v2i2.38

Abstract

Obat tradisional merupakan bahan alam dengan khasiat empiris yang telah dibuktikan secara turun temurun. Berdasarkan studi pendahuluan yang dilakukan pada tanggal 16-23 Januari 2022 terhadap 190 responden di RW 03 Kauman, Nganjuk diperoleh hasil yakni 52,63% obat tradisional untuk pengobatan degeneratif, 28,42% untuk pengobatan batuk, pilek, serta diare, sedangkan 18,95% sebagai kosmetik. Penelitian ini bertujuan untuk mengetahui tentang tingkat pengetahuan dan pola penggunaan obat tradisional sebagai terapi komplementer penyakit degeneratif di RW 03 Kauman, Nganjuk. Pengambilan sampel menggunakan total populasi yakni 100 orang dengan instrumen berupa kuesioner tertutup. Hasil penelitian diperoleh bahwa pola penggunaan obat tradisional sebagai terapi komplementer penyakit degeneratif pada warga RW 03 Kauman Nganjuk dengan keluhan terbanyak yakni penyakit hiperurisemia 34%, waktu penggunaan rutin tercatat 38%, jenis bahan obat tradisional yang paling sering digunakan daun salam (Eugenia polyantha) 31%, jenis sediaan berupa bahan segar/kering 85%. Sumber perolehan bahan obat tradisional dari membeli di pasar 42%, sumber informasi penggunaan obat tradisional paling banyak di dapat dari keluarga 41%. Cara pembuatan dengan direbus 65%, penggunaan obat tradisional karena telah merasakan manfaatnya mulai membaik 94%. Responden yang tidak mengalami efek samping obat tradisional 98%. Tingkat pengetahuan baik sebanyak 8%, sedang 79% dan rendah 13%.
Formulation and Organoleptic Evaluation of Roselle (Hibiscus sabdariffa) Jamu Godog with Stability and Microbial Quality Assessment Irianto, Iramie Duma Kencana; Purwanto; Nurhaeni, Farisya; Ana Mardiyaningsih; Bangkit Ary Pratama; Fiqoh, Latifah Nisa; Febriana Ardiyanti
Journal of Fundamental and Applied Pharmaceutical Science Vol. 6 No. 1 (2025): August
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/jfaps.v6i1.22102

Abstract

Jamu is a traditional medicinal preparation proven to have many pharmacological properties and is widely used in Indonesian society. Unfortunately, many people do not like herbal medicine because of its unpleasant taste and odor. This phenomenon has driven much research in modifying the organoleptic parameters of jamu to make it more acceptable to the tongues and noses of consumers while still having a potent effect on health. This study, thus, aimed to formulate a roselle (Hibiscus sabdariffa)-enhanced jamu godog (traditional Indonesian herbal decoction) and evaluate its organoleptic properties, physical stability, and microbial quality. Jamu godog was prepared by sequentially boiling and mixing ground ginger, turmeric, lemongrass, roselle, rock sugar, and lime, with roselle concentrations set at 0%, 0.3%, and 0.6%. Organoleptic attributes and pH stability were assessed before and after storage at 4°C and 25°C for seven days. Microbial contamination was measured via total plate count (TPC) after storage at 4°C for three and seven days. A hedonic test with 40 participants across two age groups evaluated sensory acceptance. Results indicate that the addition of roselle at 0.3% concentration optimized taste and overall acceptability while maintaining pH stability and microbial safety within BPOM standards throughout the storage period. This formulation demonstrates potential as a palatable and microbiologically safe herbal preparation with enhanced consumer acceptance.  
Antibacterial Activity of Ethanolic Extract, n-Hexane Fraction, and Chloroform Fraction of Binahong Leaves (Anredera Cordifolia) on Escherichia Coli and its Phytochemical Screening Pramita Yuli Pratiwi; Ana Mardiyaningsih; Nur Ismiyati; Hery Setiyawan
Jurnal Jamu Indonesia Vol. 6 No. 2 (2021): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v6i2.207

Abstract

Binahong leaves (Anredera cordifolia (Ten.) Steenis) are known to contain antibacterial activity compounds. The compounds contained in binahong leaves include flavonoids, alkaloids, saponins, and tannins. Escherichia coli is a gram-negative bacteria that often causes infections such as diarrhea. The purpose of this study was to determine the effect of ethanolic extract, n-hexane fraction, and chloroform fraction of binahong leaves on the growth of Escherichia coli bacteria and its phytochemical screening This research used ethanolic extract, hexane fraction and chloroform fraction of binahong leaves against Escherichia coli bacteria with concentrations of 12.5, 25 and 50% The positive control was chloramphenicol and the negative control was DMSO The method used disk diffusion technique, marked the presence of clear areas around the paper disc that showed an obstacle to bacterial growth phytochemical screening of alkaloids, flavonoids, saponins and tannins using a test tube. The result showed antibacterial activity against the growth of Escherichia coli with the diameter of the inhibition zone at concentrations of 12.5, 25, and 50%, namely the hexane fraction of 8.16; 9.73 and 12.93 mm. At the chloroform fraction 7.67; 8.47 and 9.87 mm. and the ethanolic extract of 7.33; 9.95 and 13.32 mm. The result of the largest inhibition zone was the ethanolic extract of binahong leaves with a concentration of 50%. The results of phytochemical screening using a test tube showed that the compounds contained in the ethanolic extract were flavonoids, alkaloids, saponins, and tannins.
Co-Authors Bangkit Ary Pratama Farisya Nurhaeni Febriana Ardiyanti Fiqoh, Latifah Nisa Hery Setiyawan Iramie Duma Kencana Irianto Nur Ismiyati Pramita Yuli Pratiwi Purwanto Resmi Aini Rina Widiastuti Vertika Susandy Yunisa Djayanti Putri