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All Journal International Journal of Clinical Inventions and Medical Sciences (IJCIMS) Jurnal Pengabdian Kepada Masyarakat Sisthana
Zulfah, Khairina
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Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Superoxide Dismutase from Marine as a Cytotoxic Agent Apriani, Dwi Wulan; Indrayati, Ana; Herdwiani, Wiwin; Rendati, Hema Novita; Zulfah, Khairina
International Journal of Clinical Inventions and Medical Sciences (IJCIMS) Vol 6 No 2: September 2024
Publisher : Lamintang Education and Training Centre, in collaboration with the International Association of Educators, Scientists, Technologists, and Engineers (IA-ESTE)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36079/lamintang.ijcims-0602.680

Abstract

The prevalence of cancer in Indonesia has shown an increase from 1.4 per 1000 population in 2013 to 1.79 per 1000 population in 2018. 70% of our planet is covered by unparalleled air and marine biodiversity. Therefore, medical researchers have focused on the marine world which has great potential, in the last six decades (Sagar et al. 2010). To find out other uses of biota, it is necessary to study the SOD of marine biota that reacts with their metal cofactors, to determine the specific SOD of some biota, to determine the SOD cytotoxic activity of several marine biota, to determine the mechanism of SOD of marine biota as anticancer. This literature review was carried out in several stages: formulating problems, collecting, evaluating, analyzing, and synthesizing data. The data sources used are international journals from publishers such as Science Direct, Elseiver, and SpringerLink between 2010 and 2021. The literature results obtained for the SOD classification of marine biota based on metal cofactors are 1,092 articles. The articles obtained will be selected and 52 articles that meet the inclusion criteria will be reviewed. The results of the search for specific SOD activities from marine biota were obtained by 1,243 articles. 13 articles that meet the inclusion criteria and will be reviewed. The results of the search for SOD cytotoxic activity from marine biota obtained 2,199 articles. 7 articles that met the inclusion criteria will be reviewed. The search results for specific SOD activities from marine biota were 2,496 articles. 8 articles that meet the inclusion criteria and will be reviewed. The results showed that SOD from marine biota had cytotoxic activity.
PENGARUH PENYULUHAN KESEHATAN TERHADAP TINGKAT PENGETAHUAN PENYAKIT OSTEOARTHRITIS Damayanti, Dyah Ayu Kusuma; Syafiq, Bakri As; Fauziyah, Atina; Ardhiani, Miftah Rizky; Zulfah, Khairina; Setiarahmawati, Farah Hanifah; Herawati, Isnaini; Pristianto, Arif
JURNAL PENGABDIAN KEPADA MASYARAKAT SISTHANA Vol. 4 No. 2 (2022): Desember : Jurnal Pengabdian Kepada Masyarakat Sisthana
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/pkmsisthana.v4i2.142

Abstract

Osteoartritis lutut adalah penyakit degeneratif kronis yang banyak diderita orang dewasa yang lebih tua, dan ditandai dengan kerusakan tulang rawan pada sendi lutut. Pasien mungkin mengalami nyeri sendi, kekakuan, dan deformitas sendi. Harapan diadakannya penyuluhan ini agar masyarakat bisa memahami bagaimana cara penanganan saat mengalami keluhan. Kegiatan pengabdian Masyarakat ini berupa penyuluhan dan pemberian terapi latihan dengan kompres air hangat dan isometric exercise dengan menggunakan media leaflet dan demo teknik pencegahan nyeri. Penyuluhan ini dilakukan di Kelurahan Kauman, Kabupaten Batang, kepada ibu-ibu Dawis RT 01/ RW10 yang berjumlah 10 orang. Berdasarkan data yang diperoleh, menunjukkan bahwa lebih dari 6 orang ibu-ibu dawis mengeluhkan nyeri lutut. Peningkatan pemahaman dan pengetahuan masyarakat tentang fisioterapis dan nyeri lutut atau osteoarthritis diukur dengan kuesioner pre test dan post test. Hasil penelitian ini menunjukkan bahwa pada pre test pemahaman peserta hanya 21% dan mengalami peningkatan menjadi 54% setelah dilakukan post test atau setelah pemberian materi tentang osteoarthritis. Disimpulkan bahwa kegiatan penyuluhan yang telah dilakukan mampu meningkatkan pemahaman masyarakat tentang osteoarthritis.
Co-Authors Ana Indrayati Apriani, Dwi Wulan Ardhiani, Miftah Rizky Arif Pristianto Damayanti, Dyah Ayu Kusuma Fauziyah, Atina Isnaini Herawati Rendati, Hema Novita Setiarahmawati, Farah Hanifah Syafiq, Bakri As Wiwin Herdwiani