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All Journal Jurnal Mahasiswa Farmasi Fakultas Kedokteran dan Ilmu Kesehatan UNTAN Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional Pharmascience Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Jurnal Ilmu Kedokteran dan Kesehatan Jurnal Ilmu Kefarmasian Indonesia Journal Syifa Sciences and Clinical Research (JSSCR) Medical Sains : Jurnal Ilmiah Kefarmasian Media Farmasi Indonesia Pharmaceutical Sciences and Research (PSR) Medical Sains : Jurnal Ilmiah Kefarmasian Journal Pharmacy of Tanjungpura
Mohamad Andrie
Departement Of Pharmacy, Faculty Of Medicine, Tanjungpura University, Pontianak, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health Other

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Journal : Indonesian Journal of Pharmaceutical Science and Technology

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The Effect of BHA as an Antioxidant to the Accelerated Stability Test of Snakehead Fish and Kelulut Honey Ointment Taurina, Wintari; Andrie, Mohamad; Mukkaromah, Siti
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 1 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i1.37776

Abstract

The ointment of snakehead fish extract and kelulut honey has a synergistic potential to boost the wound recuperation process. This ointment is formulated for topical use to be easily applied to the wound area. The ointment base used in this preparation is adeps lanae. Adeps lanae is an easily oxidized substance that can cause the preparation to become unstable. The addition of antioxidants is one way to prevent the oxidation process in the preparation. This has a look at aims to decide the impact of the addition of BHA as an antioxidant in the ointments of snakehead fish extract (Channa striata) and kelulut honey (Heterotrigona itama) at 28 days of storage with an accelerated stability test method with a temperature 40 ± 20C and RH 75 ± 5%. The ointment was made with various concentrations of BHA 0.005% (F1), 0.01% (F2), and 0.02% (F3) then tested the physical properties of the ointment and analyzed by SPSS. Results of spreadability test analysis showed an increase of the spread and significant differences between F1, F2, and F3 to F0. The adhesion test analysis results showed a decrease in the stickiness of time bonding strength and a significant difference. The test results showed a decrease in acid number on the acid number F2 and F3. Results of the organoleptic test, homogeneity, and power protection showed that all formulas have good stability. F2 is the best formula to prevent oxidization of the dosage indicated by the smallest value of the acid number.
Co-Authors Agung Endro Nugroho Agung Endro Nugroho Anggareni, Anggareni Anjeli, Lea Annisa Mutia Yusran Argo, Septian Fernando Arifani, Nata Hadiati Aulia, Yunita Hananda Bambang WIJIANTO Dies Sihombing Dies Sihombing, Dies Dwi Wulandari Dyah Ayuningtias Ely lisnawati Emy OKTAVIANI Firda M. Hadad Fransisca Daisa Hedaya, Angelina Putri Ignatius Ryan Adriawan Ignatius Ryan Adriawan, Ignatius Ryan Juliferd Gredi Lea Anjeli Mardiansyah, Furqaan Maya Widya Astuti Wulandari Mukkaromah, Siti Naziella Naziella Nur Firdiena Titian Ratu Nurlaila Afriliah Nurmainah Nurmainah Nurmainah Nurmainah Pinondang Simaremare Pinondang Simaremare, Pinondang Pratama, Taufik Nanda Prisilla, Salma Rahmawati . Rina Susilowati Rinaldy, Iqmal Arfan Risma Dwi Anugerah Rizqa Ayunda Rizqa Ayunda, Rizqa Rusmini Rusmini Saragi, Restian Rony Suprawijaya, Perianus Suwidjiyo Pramono Suwidjiyo Pramono Taufik Nanda Pratama Wintari , Wintari Wintari Taurina