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All Journal Jurnal Hortikultura Indonesia (JHI) Indonesian Journal of Pharmacology and Therapy
Dewa Ngurah Suprapta
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Agriculture, Biological Sciences & Forestry Immunology & microbiology Medicine & Pharmacology

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Pertumbuhan dan Produksi Bunga Marigold (Tagetes erecta L.) pada Berbagai Frekuensi Pinching dan Jenis Pupuk: Growth and Flower Yield of African Marigold (Tagetes erecta L.) under Different Pinching Frequencies and Fertilizer Types Dewi Sukma; Syarifah Iis Aisyah; Muhamad Syukur; Dewa Ngurah Suprapta; Muthi'ah Khairun Nisa
Jurnal Hortikultura Indonesia (JHI) Vol. 14 No. 3 (2023): Jurnal Hortikultura Indonesia
Publisher : Indonesian Society for Horticulture / Department of Agronomy and Horticulture

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jhi.14.3.141-148

Abstract

Pengaruh frekuensi pinching dan jenis pupuk terhadap pertumbuhan dan produksi T. erecta varietas (var.) Sudamala Oranye 1 perlu diketahui karena pelepasan varietas umumnya diiringi sistem budidaya yang sesuai dengan karakteristik tanaman. Penelitian dilaksanakan di Kebun Percobaan CV. Benih Dramaga, Desa Sinar Sari, Kecamatan Dramaga, Kabupaten Bogor, Jawa Barat pada bulan Maret hingga Juli 2023. Percobaan dilakukan pada T. erecta var. Sudamala Oranye 1 dengan bahan tanam setek menggunakan Rancangan Kelompok Lengkap Teracak (RKLT) faktorial dengan frekuensi pinching sebanyak 3 taraf, yaitu setiap 2 hari (F1), 4 hari (F2) dan 6 hari (F3) serta jenis pupuk sebanyak 2 taraf yaitu AB Mix 1000 ppm (J1) dan NPK 16-16-16 5000 + Gandasil 2000 (J2) sebagai faktor. Hasil penelitian menunjukkan frekuensi pinching berpengaruh nyata terhadap bobot kuntum serta sangat nyata terhadap diameter kuntum, sedangkan jenis pupuk berpengaruh nyata terhadap persentase tanaman terserang layu bakteri dan tanaman hidup, serta sangat nyata terhadap masa panen Sudamala Oranye 1 Pengamatan secara kualitatif pada kedua varietas menunjukkan adanya perbedaan warna daun dan mahkota bunga akibat jenis pupuk. Pinching setiap 2 hari memiliki komponen hasil tertinggi pada T. erecta varietas Sudamala Oranye 1 walaupun tidak berbeda nyata dengan frekuensi lainnya. Pemberian pupuk AB Mix 1000 ppm menghasilkan produksi tertinggi pada T. erecta varietas Sudamala Oranye 1.Kata kunci: AB Mix, gandasil, NPK, pembuangan kuncup, setek
The potential of polyphenols from natural ingredients against SARS-CoV-2 infection: A review Hendrayana, Made Agus; I Made Jawi; Dewa Made Sukrama; Dewa Ngurah Suprapta
Indonesian Journal of Pharmacology and Therapy Vol 2 No 3 (2021): Special Issue: COVID-19
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.2310

Abstract

All countries in the world are facing the coronavirus disease-19 (COVID-19) pandemic which has resulted in various crises. To date, there is no effective treatment in controlling COVID-19. Many clinical trials of approved drugs against COVID-19 were conducted. However, the results were inconclusive, even severe adverse effects were reported. The new effective drugs are therefore urgently needed. Herbal medicines have been widely used by community to enhance the body immune system during COVID-19 pandemic. Polyphenols are large group of active compounds found in the natural ingredients. These compounds have been proven to have biological activity against various pathogen infections including viral infection. During COVID-19 pandemic, various polyphenol compounds from various medicinal plants have been investigated for their activity against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) both in silico and in vitro. Among the polyphenols investigated, some of them namely papyriflavonol, catechin gallate, gallocatechin gallate, luteolin, quercetin, tangeretin, naringenin, herbacetin, emodin, eriodyctiol, fenoterol, baicalin, myricetin, quercetagetin exhibited strong activity against SARS-CoV-2. The possibilities of mechanism of actions as antiSARS-CoV-2 of these polyphenols were 1) bind to the N protein causing the inhibition of viral transcription and replication; 2) inhibit the binding of S protein to ACE2 receptors preventing the entry of the virus into the host cells; 3) inhibit 3CLpro function inhibiting the viral transcription and maturation; and 4) bind directly to the ACE2 receptor. In conclusion, some polyphenol compounds from nature ingredients are potential to develop to be future antiSARS-CoV-2. However, further the pre-clinical and clinical studies are required to strengthen existing evidence.
Co-Authors Dewi Sukma I Dewa Made Sukrama I Made Jawi Made Agus Hendrayana Muhamad Syukur Muthi'ah Khairun Nisa Syarifah Iis Aisyah