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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. JURNAL PENDIDIKAN GLASSER
Nimim
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Education Health Professions Medicine & Pharmacology Public Health

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Synergistic Potential Of Bioactive Compounds Of Nut Grass Tuber Extract (Cyperusrotundus) As Anti-Leukemia Herbal Medicine Agustini, S. M.; Tri Aini Fadjrin Juliani; Nimim; Patmawati
Saintika Medika Vol. 17 No. 2 (2021): December 2021
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/sm.Vol17.SMUMM2.18805

Abstract

Leukemia treatment strategies have developed rapidly. Both the intensity of the dose and the duration of intensive treatment have been maximized after decades of trials optimizing chemotherapy options, dose intensity, and duration of treatment. The emergence of multidrug-resistant cancer cells (MDR) results in the higher costs needed in the treatment of AML patients. The purpose of this study was to identify and evaluate the potential of active compounds from Cyperus rotundus on the activity of the Acute Myeloid Leukemia (AML) cell line HL-60 APL through inhibition of proliferation, cell cycle, differentiation, and induction of apoptosis in the treatment of AML. The bioavailability of the compound to be taken orally was analyzed by Human Intestine Absorption (HIA+). Potential pathways inhibiting proliferation, cell cycle, differentiation, and induction of apoptosis in the treatment of AML were analyzed using a Structure-Activity Relationship approach with the PASS SERVER program. Pathway analysis was carried out using STITCH and Cytoscape v.3.5.1 programs. The study results showed that nutgrass has six active compounds quercetin, luteolin, apigenin, camphor, sitosterol, and gallic acid, synergizing the main pathway of cell activity (Pa>0.7).Conclusion of Cyperus rotundus extract has a high potential synergistically as an anti-leukemia herbal medicine.
ISLAMIC RELIGIOUS EDUCATION TEACHER STRATEGIES IN DEVELOPING STUDENT CHARACTER EDUCATION Haluti, Farid; Mufarrihah, Anik; Nimim
JURNAL PENDIDIKAN GLASSER Vol. 8 No. 1 (2024)
Publisher : Fakultas Keguruan dan Ilmu Pendidikan Universitas Muhammadiyah Luwuk

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32529/glasser.v8i1.3265

Abstract

Islamic religious education teachers' strategies in developing character education in students may involve a deep understanding of Islamic religious values that include ethics, morals and manners. These teachers may understand that strong character in accordance with Islamic teachings can form individuals who are religious, responsible, disciplined and honest. The purpose of this study is to analyze the role and strategies used by Islamic Religious Education teachers in developing students' character education at SDN Bulungkobit. The method used is qualitative type, where data collection is done through documentation, interviews, and observation. Data analysis was carried out through the stages of collecting data, reducing data, presenting data and concluding and verifying. From the results of the study, it can be concluded that the strategies carried out by Islamic Religious Education teachers in shaping character are through integration, through daily activities which include modeling, habituation, reprimand, advice, and environmental conditioning that supports the formation of student character
Co-Authors Agustini, S. M. HALUTI, FARID MUFARRIHAH, ANIK Patmawati Tri Aini Fadjrin Juliani