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All Journal CRJIM (Clinical and Research Journal in Internal Medicine)
Raharjo, Fajar Maulana
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Education Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Other

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The Outcome of Primary Hyperaldosteronism in Resistant Hypertension with Efficiency Cost in Clinical Practices A Case Report Raharjo, Fajar Maulana; Lil Alamin, Rahmatan; Gunawan, Michelle; Nur Samsu
Clinical and Research Journal in Internal Medicine Vol. 6 No. 1 (2025): Volume 6 No 1, May 2025
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2025.006.01.13

Abstract

Aldosterone as a major mineralocorticoid has an important role in regulating circulating volume and potassium homeostasis, especially in the kidney. Manifestation of hypertension and hypokalemia in the young age population must be considered about the role of Aldosterone. This case report will discuss a patient with uncontrolled hypertension with severe hypokalemia who was treated with 3 kinds of antihypertensive drugs but the blood pressure is still high. After performing several diagnostic tests, the Aldosterone level was significantly high and left an adrenal tumor from an abdominal MRI. The patient treated with mineralocorticoid receptor antagonists or Spironolactone 25mg daily and show controlled blood pressure.
Pellagra Syndrome in Geriatric Patient: Insights from Pathogenesis and Diagnosis Raharjo, Fajar Maulana; Soenarti, Sri; Winoto, Eden Suryoiman; Adriansyah, Vito; Aditya, Muhammad Reva
Clinical and Research Journal in Internal Medicine Vol. 7 No. 1: Volume 7 No 1, May 2026
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2026.007.01.14

Abstract

Pellagra syndrome is a chronic niacin deficiency disease that is often underdiagnosed. We report a case of an 83-year-old woman presenting with the four classic symptoms (4D) of pellagra: dermatitis (Casal’s necklace), diarrhea, dementia, and a risk of death if left untreated. The patient also had severe malnutrition, multiple infections, and a history of stroke for five years. The diagnosis was established based on clinical findings and a history of inadequate nutritional intake. Management included fluid therapy, antibiotics, medical rehabilitation, enteral and parenteral nutrition, as well as niacin supplementation. Following treatment, the patient showed clinical improvement, including stabilization of hemoglobin levels. This case highlights the importance of early detection and understanding the pathogenesis of Pellagra syndrome to improve patient outcomes and quality of life. Keywords: Casal’s Necklace, Dementia, Malnutrition, Niacin, Pellagra syndrome
Co-Authors Aditya, Muhammad Reva Adriansyah, Vito Lil Alamin, Rahmatan Michelle Gunawan, Michelle Nur Samsu Sri Soenarti Winoto, Eden Suryoiman