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All Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) The Journal of Society Medicine (JSOCMED)
Pangaribuan, Jessica Patricia
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Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Effect of Glycemic Parameters on Mortality of Type 2 Diabetes Mellitus Patients with COVID-19 Infection in Haji Adam Malik Hospital Medan Pangaribuan, Jessica Patricia; Syafril, Santi; Lubis, Dian Anindita; Isnanta, Rahmad; Rey, Imelda
Journal of Society Medicine Vol. 2 No. 8 (2023): August
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v2i8.81

Abstract

Introduction: Diabetes Mellitus Type 2 (DM T2) is a major health problem, especially in people in developing countries. DM T2 is the most frequently reported comorbid disease in patients with COVID-19. The relationship between DM T2 and poorer outcome in COVID-19 infection is thought to be because hyperglycemia and chronic inflammation impair control of viremia and inflammation by weakening the immune response. This research aim to determine the effect of glycemic parameters on the mortality of DM T2 patients with COVID-19. Method: This research is a descriptive analytic study with a retrospective design which was carried out at the H. Adam Malik General Hospital in Medan. The data obtained was analyzed statistically and said to be statistically significant if p <0.05. Results: Based on the results of the study, there were significant differences in the values of inflammatory markers such as leukocytes, neutrophils, NLR, PCT, LDH, D-dimer, ferritin, SGOT, urea and creatinine in the severity of COVID-19 patients and there were significant differences in the mean fasting blood sugar, blood sugar 2PP, in moderate, severe and critical COVID-19 patients. Conclusion: Glycemic parameters in patients who died were worse than patients who recovered, although the statistical results were not significantly different.
Postpartum Thyroiditis: A Case Report Pangaribuan, Jessica Patricia; Santi Syafril
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (536.002 KB) | DOI: 10.32734/jetromi.v3i2.5476

Abstract

ABSTRACT: Background: Postpartum thyroiditis (PPT) is a thyroid dysfunctionn syndrome which is temporary or permanent that occurs 1 year after giving birth or abortion. The occurrence of postpartum thyroiditis is 5 – 10% of postpartum women in the world. It is caused by an inflammation of the thyroid gland which leads to a destruction of the thyroid follicle and proteolysis of thyroglobulin. Case presentation: A woman, 31 years old, was admitted to the hospital complaining an enlargement on her neck. The patient said her the enlargement keeps getting larger and she also complained a feeling of something stuck in the throat. The patient also complained a hoarse voice. The patient has just given birth of her second child 5 months ago. From a hematologic examination, radiologic, and blood culture, the patient was diagnosed with Postpartum Thyroiditis. The patient was given Euthyrox therapy and will undergo repeated evaluation after 1 months of the therapy. Conclusion: We reported a case of Postpartum Thyroiditis that was treated comprehensively, and showed a good prognosis.
Correlation between HbA1C and D-dimer in Type 2 Diabetic with COVID-19 Patients Pangaribuan, Jessica Patricia; M. Aron Pase
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 4 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (783.826 KB) | DOI: 10.32734/jetromi.v3i4.7529

Abstract

Background: Coronavirus disease-19 (COVID-19) is the disease caused by 2019-nCoV/SARS-CoV-2, a novel β corona- virus of group 2B . COVID-19 has been reported to be associated with severe condition with type 2 diabetes mellitus (T2DM). D-dimer is a by product of fibrin degradation. It is widely recognized as a biomarker for thromboembolism and as a prognostic marker for critical patients. Methods: This study uses secondary data, which is obtained by looking at the contents of patient medical records at H. Adam Malik Medan Hospital between 2020-2021. The population of this study was all inpatients confirmed COVID-19 through an RT-PCR SARS-CoV-2 swab examination. The study sample was obtained by the total sampling method, where all populations that meet the criteria of inclusion and exclusion are used as research samples. Patients were triaged as per severity on basis of national guidelines: asymptomatic, Mild (respiratory rate < 24/min, SpO2 >94% at room air), moderate (respiratory rate: 24-30/min, SpO2 90-94% at room air) and severe (respiratory rate >30/min SpO2 < 90%), ARDS and septic shock [6]. HbA1c implementation using HPLC methods and D-dimer is measured by ELISA method. Result: There were 163 patients consisting of 92 men and 71 women, the average age was 56.9±10.3 years, and HbA1c, FPG and PPG remained uncontrolled. There were no differences in age parameters of blood sugar profiles and D-dimers between men and women. D-dimers are significantly negatively correlated with PPG. Conclusion: Age, blood sugar profile and D-dimer did not differ significantly between men and women, and D-dimer had a correlation significantly with PPG on T2DM with COVID-19 patients. Keywords : D-dimer, T2DM, COVID-19
Co-Authors Imelda Rey Lubis, Dian Anindita Muhammad Aron Pase Rahmad Isnanta, Rahmad Santi Syafril Santi Syafril, Santi