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All Journal Jurnal AFAMEDIS Jurnal Ilmu Kesehatan dan Gizi
Ismu dwi supangkat
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Health Professions Medicine & Pharmacology

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COST-EFFECTIVENESS ANALYSIS BIAYA PENGOBATAN EPILEPSI JENIS GRAND MAL DENGAN BEBERAPA OBAT ANTI EPILEPSI DI RAWAT INAP RSUD SIDOARJO Andri Priyoherianto; Ismu dwi supangkat
AFAMEDIS Vol. 2 No. 2 (2021): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (212.912 KB)

Abstract

Epilepsy is a neurological disoder that arises suddenly and periodically, ussualy with change in consciousesness. Different use of anti-epileptic drugs by patients results in patient’s medical cost increase. The use expensive anti-epileptic drugs does not guarantee the effectiveness of patient care, therefore a research needs to be done to determine which anti-epileptic drugs therapy is more cost-effective between Valproic Acid, Na Fenitoin, and combination Na Fenitoin + Valproic Acid in hospitalized epileptic patients in RSUD Sidoarjo. The Research was a retrospective observational study with retrospective data retrieval. The research was conducted a medical Record retrieval at SIM RS from January 2020- December 2020. The samples in this study were 30 patients with 7 patients using Valproic Acid, 6 patients using Na Fenitoin, and 17 patient using combination Na Fenitoin + Valproic Acid. The results showed that the more cost- effective therapy between Valproic Acid, Na Fenitoin and combination Na Fenitoin + Valproic Acid in the treatment of epileptic in RSUD Sidoarjo was therapy with combination Na Fenitoin + Valproic Acid, which can be seen from ACER ( Average Cost-Effectiveness Ratio) combination Na Fenitoin + Valproic Acid Rp Rp. 880.854 /effectiveness compared with Valproic Acid ACER value of Rp. 977.307/effectiveness and Na Fenitoin Rp. 979.546/effectiveness. The lowest ICER value on combination Na Fenitoin + Valproic Acid was Rp.-994.290. Keywords : Cost-effectiveness analysis, Combination Na Fenitoin + Valproic Acid, Epileptic
Uji Aktivitas Antibakteri Ekstrak Akar Kuning (Arcangelisia Flava Merr.) Terhadap Bakteri Escherichia Coli Siti Marita Ubaid; Zakiyatul Hamidah; Erliyananda Pretty Desi; Panji Ratih Suci; Ismu Dwi Supangkat
Jurnal Ilmu Kesehatan dan Gizi Vol. 2 No. 2 (2024): April : Jurnal Imu Kesehatan dan Gizi
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/jikg.v2i2.2841

Abstract

Arcangelisia flava Merr, which has been known empirically by the Dayak community in Central Kalimantan as natural herbs. This study aimed to determine the antibacterial effect of the Arcangelisia flava Merr extract against Escherichia coli. This study used two concentration of 25% and 50%, Ciprofloxacin as a positive control and water for injection as a negative control. The existence of the effect of the Arcangelisia flava Merr. extract against bacteria Escherichia coli is characterized by the formation of inhibition zone at a concentration of 25% obtained by the mean 2,005 mm, concentration of 50% obtained by the mean 2,435 mm, positive control obtained mean 7,975 mm, while for the negative control has no effect on Escherichia coli. The results showed that the Arcangelisia flava Merr. can significantly inhibit the growth of Escherichia coli bacteria. And there was the tendency of an increase in the concentration of Arcangelisia flava Merr. The higher concentration of Arcangelisia flava Merr. Extract the higher the resulting inhibit zone.
Co-Authors Andri Priyoherianto Erliyananda Pretty Desi Panji Ratih Suci Siti Marita Ubaid Zakiyatul Hamidah