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COST-EFFECTIVENESS ANALYSIS BIAYA PENGOBATAN EPILEPSI JENIS GRAND MAL DENGAN BEBERAPA OBAT ANTI EPILEPSI DI RAWAT INAP RSUD SIDOARJO Andri Priyoherianto; Ismu dwi supangkat
AFAMEDIS Vol. 2 No. 2 (2021): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Epilepsy is a neurological disoder that arises suddenly and periodically, ussualy with change in consciousesness. Different use of anti-epileptic drugs by patients results in patient’s medical cost increase. The use expensive anti-epileptic drugs does not guarantee the effectiveness of patient care, therefore a research needs to be done to determine which anti-epileptic drugs therapy is more cost-effective between Valproic Acid, Na Fenitoin, and combination Na Fenitoin + Valproic Acid in hospitalized epileptic patients in RSUD Sidoarjo. The Research was a retrospective observational study with retrospective data retrieval. The research was conducted a medical Record retrieval at SIM RS from January 2020- December 2020. The samples in this study were 30 patients with 7 patients using Valproic Acid, 6 patients using Na Fenitoin, and 17 patient using combination Na Fenitoin + Valproic Acid. The results showed that the more cost- effective therapy between Valproic Acid, Na Fenitoin and combination Na Fenitoin + Valproic Acid in the treatment of epileptic in RSUD Sidoarjo was therapy with combination Na Fenitoin + Valproic Acid, which can be seen from ACER ( Average Cost-Effectiveness Ratio) combination Na Fenitoin + Valproic Acid Rp Rp. 880.854 /effectiveness compared with Valproic Acid ACER value of Rp. 977.307/effectiveness and Na Fenitoin Rp. 979.546/effectiveness. The lowest ICER value on combination Na Fenitoin + Valproic Acid was Rp.-994.290. Keywords : Cost-effectiveness analysis, Combination Na Fenitoin + Valproic Acid, Epileptic
UJI AKTIVITAS ANTIDIABETES KOMBINASI EKSTRAK ETANOL DAUN ECENG GONDOK (Eichhornia crassipes (Mart.)Solms) DAN DAUN SINTRONG (Crassocephalum crepidioides (Benth.) S. Moore) PADA MENCIT Andri Priyoherianto; Panji Ratih Suci; Putri Rizki Cahya Fatimah; Atik Nur Wijayanti
Jurnal Insan Farmasi Indonesia Vol 4 No 1 (2021): Jurnal Insan Farmasi Indonesia
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jifi.v4i1.602

Abstract

Diabetes mellitus is a chronic metabolic disorder that occurs due to destruction of pancreatic ? cells characterized by blood glucose levels that exceed normal limits. The purpose of this study was to determine the therapeutic effect of the combination of water hyacinth leaf extract and Sintrong leaf in reducing blood glucose levels in alloxan-induced experimental animals. Water hyacinth leaf powder and Sintrong leaves were extracted using the maceration method with 70% ethanol as a solvent. A total of 25 mice were divided into 5 groups, namely negative control CMC-Na 0.5%, positive control glibenclamide 0.00065 mg / g BW, water hyacinth leaf extract 17.5 mg / kg BW, Sintrong leaf extract 10.5 mg/ kg BW and a combination of water hyacinth leaf extract 17.5 mg / kg BW and sintrong leaf 10.5 mg / kg BW. The results showed that a single extract of water hyacinth and Sintrong leaves was able to reduce blood sugar levels for 7 days. The combination dose was effective in reducing blood sugar levels with a combination dose of 17.5 mg/ kg water hyacinth leaf extract in combination for 7 days.
PENENTUAN AKTIVITAS TABIR SURYA DAN ANTIOKSIDAN EKSTRAK ETANOL BENALU (Henslowia frutescens) INANG JERUK BALI SECARA IN VITRO Henny Nurhasnawati; Rusdiati Helmidanora; Yullia Sukawaty; Andri Priyoherianto; Elly Purwati
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 6 No 1 (2021): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (315.661 KB) | DOI: 10.36387/jiis.v6i1.647

Abstract

Henslowia frutescens is a semi-parasitic plant, although considered harmful, it has medicinal and cosmetic potential. This plant has secondary metabolite compounds, namely phenolic compounds, flavonoids, saponins, tannins, and steroids which have high antioxidant activity. The purpose of this study was to determine the sunscreen activity of the ethanol extract of Henslowia frutescens based on the in vitro SPF (Sun Protecting Factor) value and to determine its antioxidant activity. The research stages included sampling, sampling, maceration extraction with 95% ethanol, yield calculation, phytochemical screening, sunscreen activity test based on SPF value, and antioxidant activity test. Data analysis was carried out descriptively based on the measurement results processed according to the calculation formula. The results showed that the sunscreen activity of the ethanol extract of Henslowia frutescens based on the in vitro SPF value was 14.57 - 25.20 with moderate protection category. The antioxidant activity of the ethanol extract of Henslowia frutescens showed a very strong category with an IC value of 22.82 ± 1.33.
Gambaran Waktu Tunggu Pelayanan Resep Non Racikan di Instalasi Farmasi Rawat Jalan Rumah Sakit X Sidoarjo pada Bulan Maret Tahun 2019. Andri Priyoherianto; Abdul Ghani Rizky rahadianto
AFAMEDIS Vol. 2 No. 1 (2021): Jurnal Farmasi Indonesia Afamedis
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

One of the standard pharmaceutical services in hospitals is waiting time. The waiting time for the drug service is the grace period for the patient to submit the prescription until receiving the drug. Waiting time has an effect on service quality and patient satisfaction. This study aims to evaluate the implementation of Hospital Minimum Service Standards (SPM) with the types of pharmacy services in the old category of waiting time for outpatient prescription services at Sidoarjo X Hospital. This research is a non-experimental study with a descriptive design for patients with outpatient cooperative insurance prescriptions in Pharmacy Hospital Sidoarjo Hospital and sampling using the probability sampling method, namely simple random sampling. The time of the study was in March 2019. The calculation of the waiting time for prescription drug services was carried out and then an analysis of the suitability of service standards was carried out with a minimum length of time waiting category The number of recipes examined in this study were 379 prescriptions which were prescriptions for finished or non-concocted drugs. The average waiting time for finished or non-concocted drugs is 18.66 minutes. This is in accordance with the minimum service standards required by Kepmenkes No.129 / Menkes / SK / II / 2008 concerning prescription services for both finished drugs and concoction drugs, namely the length of waiting time for finished drugs ≤30 minutes and concoction drugs ≤60 minutes, and from the average sample studied there was no longer the waiting time as required.
Antihyperuricemic Activity Of Ficus Carica Leave Extract in Mus Musculus Andri Priyoherianto
NERSMID : Jurnal Keperawatan dan Kebidanan Vol. 1 No. 1 (2018): Mei
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Abstract

ABSTRACT Ficus carica L. is one of the many plants containing flavonoid compounds. The benefits of flavonoids here are inhibiting free radicals by inhibiting enzymes responsible for the production of superoxide radicals such as xanthine oxidase. The aim of this research is to know the effect of Tin leaf extract (Ficus carica L.) on the level of uric acid mice (Mus musculus) induced by homogenate of chicken liver, quail egg yolk, and jelanta oil. Mice as many as 30 tails divided into 6 groups, each consisting of 5 tails. Group 1 as normal control, group 2 as negative control was given 1% CMC-Na, group 3, 4, and 5 were given Tin leaf extract at consecutive doses of 140 mg, 420 mg, and 820 mg / KgBB. Group 6 as positive control was given allopurinol 13 mg / KgBB. Determination of uric acid levels using the calibrated EasyTouch®GCU digital tool. The percentage decrease uric acid level at dose 140 mg / KgBB, 420mg / kgBB, and 820mg / KgBB respectively is 10.4%; 11.4%; and 39.1%. Dose 820mg / KgBB gives the biggest decrease that is equal to 39,1%, if compared with other group hence positive control group that is Allopurinol give biggest decrease 57,8%. Based on the result of analysis using cruciate wallis test with significance value <0,05 indicates that there is difference of each group.
HUBUNGAN PENGETAHUAN PASIEN DI KLINIK BAPI KRIAN TERHADAPPENGGUNAAN SUPPOSITORIA PERIODE APRIL 2021 andri priyoherianto
AFAMEDIS Vol. 3 No. 2 (2022): Jurnal Farmasi Indonesia: AFAMEDIS
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Suppositories are solid pharmaceutical dosage forms that are administired rectally, generally, in the form of a torpedo and melt at body temperature. Lack of knowledge and education about suppository preparations is an important factor that affects the knowledge possed bythe general public on the use of suppostories. The research method used is by distirbuting questionnaires to patient who come to the BAPI Krian clinic with certain predetermained criteria. Using descriptive correlation method which is used toreveal the correlation relationship between variables. And the data analysis used the chi-square correlationtechnique with SPSS version 26.0 tool. The result showed that there was no significant relationshipbetween patient knowledge and how to use suppositories.Keywords: Suppository, Knowledge, Application, Patient, Descriptive Correlation,Relevancy, Chi-square.
Kesesuaian Penulisan Resep Pasien BPJS Dengan Formulrium Nasional Di Poli Penyakit Dalam Rumah Sakit Islam Hasanah Mojokerto Periode Oktober – Desember 2021 andri priyoherianto
AFAMEDIS Vol. 3 No. 2 (2022): Jurnal Farmasi Indonesia: AFAMEDIS
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Social security is a form of social protection that guarantees all Indonesian people to be able to meet the needs of a decent life. The Social Security Administration Agency (BPJS) is one of the institutions established to administer social security assistance programs in Indonesia. To overcome the imbalance between the contributions received from the community and the health costs incurred by BPJS, efforts are made to optimize BPJS patient prescribing based on the National Formulary as a reference. So that the hospital can control the quality and cost of treatment, and optimize services to patients. Research Methods: This research is a nonexperimental research that is descriptive in nature with retrospective data collection during the period October - December 2021, using the purposive sampling method, namely examining existing samples with certain considerations. The data are presented in tabular form and are described and calculated in percentage terms. A prescription is said to be in accordance with the National Formulary if all the drugs are included in the National Formulary. The results showed that the suitability of prescription writing with the National Formulary based on prescription sheets was 74.19% which was in accordance with the National Formulary and 25.81% which was not according to the National Formulary, while the conformity of prescription writing to the National Formulary based on drug items was 93.14% which was in accordance with the Formulary. National and 6.86% which is not in accordance with the National Formulary. Conclusion: The results of this study indicate that the recipes studied are not fully in accordance with the National Formulary.
TINGKAT PENGETAHUAN PASIEN TERHADAP BEYOND USE DATE (BUD) OBAT RACIKAN DI APOTEK KIMIA FARMA 180 PAHLAWAN SIDOARJO andri priyoherianto; Valiandri Puspadina; Merry Patrilinilla Chresna
AFAMEDIS Vol. 4 No. 1 (2023): JURNAL FARMASI INDONESIA AFAMEDIS
Publisher : Akademi Farmasi Mitra Sehat Mandiri Sidoarjo

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Abstract

Abstrack Almost people usually spare medicine for supplies. If medicines not stored appropriately, medications can be exposed to varying environmental changes, making them lose their efficacy and it can be harmful to consumer’s health. for example, irrational drug use and cause drugrelated problems, including the risk of medication errors. When a product is opened, assigning a Beyond Use Date (BUD) often requires by the pharmacist to determine appropriate expired date of product. This research is a descriptive observational study. Method of data collection was carried out prospectively during April 2022. This study was conducted to patient’s knowledge level of the Beyond Use Date (BUD) of compounded drugs in Kimia Farma 180 Pahlawan Pharmacy Sidoarjo. From research conducted in April 2022, many recipes were found, both mixtures of powder, capsules, ointments, and syrups. This level of knowledge is obtained based on the results of the answers from the questionnaire sheet with a total of 10 questions to patients who come to redeem prescription medicine. Based on the results of the study, with a total of 171 respondents, it can be concluded that respondents have a level of knowledge that is included in the sufficient category with a value of 53.8%.
Pelatihan Sabun Herbal Tinggi Antioksidan Berbasis Ekstrak Strawberry di Desa Waru Sidoarjo Erna Fitriany; Andri Priyoherianto
Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat Vol. 3 No. 2 (2023): Maret 2023 - Jurnal Altifani Penelitian dan Pengabdian kepada Masyarakat
Publisher : Indonesian Scientific Journal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25008/altifani.v3i2.365

Abstract

Sabun merupakan salah satu kebutuhan yang terus menerus dikonsumsi dalam rumah tangga. Ekstrak stawberry memiliki aroma segar, warna menarik, serta memiliki aktivitas antioksidan, sehingga dapat lebih efektif dalam membunuh kuman dan bakteri serta melindungi tubuh dari virus di masa pandemi seperti ini. Sabun yang berkualitas memiliki harga jual yang tinggi. Untuk mengatasi hal tersebut, pelatihan ini diadakan untuk memberikan keterampilan pembuatan sabun kepada Ibu- Ibu di Desa Waru, Sidoarjo. Tujuan dari kegiatan ini adalah untuk menambah wawasan dan keterampilan Ibu- Ibu di Desa Waru  dalam pembuatan sabun yang berkualitas. Di masa mendatang, kegiatan ini dapat dimanfaatkan oleh Ibu-Ibu Desa Waru untuk meningkatkan penghasilan tambahan, sehingga memiliki kegiatan produktif yang bernilai ekonomis. Diharapkan melalui kegiatan ini, masyarakat mampu menciptakan peluang lapangan kerja baru dan berwirausaha. Pembuatan sabun home made ini sangat mudah, bahan yang digunakan juga dapat ditemui di pasaran. Pembuatan sabun homemade ini juga dapat digunakan untuk mengurangi biaya pengeluaran rumah tangga. Sabun homemade ini memiliki harga yang lebih murah, serta dalam satu kali produksi menghasilkan sabun dalam jumlah yang banyak.
Green Synthesis AgNPs menggunakan Bioreduktor Alami Ekstrak Buah Kiwi: Biosintesis, dan Karakterisasi Erna Fitriany; Andri Priyoherianto; Valiandri Puspadina; M. Rizky Arif; Alfulaila Alfulaila; Masfah Raudlotus Shofiyyah
Justek : Jurnal Sains dan Teknologi Vol 6, No 1 (2023): Maret
Publisher : Unversitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/justek.v6i1.13918

Abstract

Abstract: Green Synthesis or Green Chemistry of silver nanoparticles (AgNPs) has many advantages, one of which is fast, easy, and cheap. AgNPs have many benefits in the health sector. AgNPs are of great interest in the field of nanoparticle development because they have good biomedical and anti-bacterial activities. Bioreductors play an important role in reducing the size of AgNPs, in this study a natural bioreductor in the form of Kiwi extract (Actinida deliciosa) was used. Purpose of the study the objective of this research was the biosynthesis of AgNPs using a kiwifruit extract bioreductor. Research methods with extraction of Kiwi, synthesis of AgNPs using Kiwi extract, characterization of AgNPs formed using UV-Visible spectroscopy (UV-Vis), Fourier-transform Infrared Spectroscopy (FTIR), and Particle Size Analyzer (PSA). Research Results that AgNP formation was confirmed by optical performance using UV-VIS spectroscopy and showed an AgNP peak at 415 nm. The C-H, C-N, and C=O groups in Actinidia deliciosa were confirmed by FTIR. The size of the AgNPs was studied using PSA and a size of 65.01 nm was obtained.Abstrak: Sintesis Hijau atau Kimia Hijau nanopartikel perak (AgNPs) memiliki banyak keuntungan, salah satunya cepat, mudah, dan murah. AgNPs memiliki banyak manfaat dalam bidang kesehatan. AgNPs menjadi perhatian besar dalam bidang pengembangan nanopartikel karena memiliki aktivitas biomedis dan anti bakteri yang baik. Bioreduktor memegang peran penting dalam mereduksi ukuran AgNPs, dalam penelitian ini digunakan bioreduktor alami berupa ekstrak Kiwi (Actinida deliciosa). Tujuan penelitian ini adalah biosintesis AgNPs menggunakan bioreduktor ekstrak buah Kiwi. Metode penelitian dengan esktraksi Kiwi, sintesis AgNPs menggunakan ekstrak Kiwi, karakterisasi AgNPs yang terbentuk menggunakan instrumen spektroskopi UV-Visible (UV-Vis), Fourier-transform Infrared Spectroscopy (FTIR), dan Particle Size Analyzer (PSA). Hasil Penelitian bahwa pembentukan AgNPs dikonfirmasi oleh kinerja optik menggunakan spektroskopi UV-VIS dan menunjukkan puncak AgNP pada 415 nm. Gugus C-H, C-N, dan C=O pada Actinidia deliciosa dikonfirmasi oleh FTIR. Ukuran AgNPs dipelajari menggunakan PSA dan diperoleh ukuran 65,01 nm.