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All Journal JPBIO (Jurnal Pendidikan Biologi) Jurnal Kefarmasian AKFARINDO Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat
Christiyani Kusumaningrum, Serafica Btari
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Humanities Education Immunology & microbiology Medicine & Pharmacology Social Sciences Other

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SINTESIS DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA KALKON TERHADAP BAKTERI KONTAMINAN PRODUK DARAH GRAM NEGATIF DAN POSITIF Wiwit Sepvianti; Christiyani Kusumaningrum, Serafica Btari
Jurnal Kefarmasian Akfarindo Vol 7 No 1 (2022)
Publisher : Akademi Farmasi Indonesia Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37089/jofar.vi0.112

Abstract

Background: The development of chalcone-based antibiotics has been widely carried out today, variations in the location and type of functional groups were carried out to find chalcone with the best bacterial inhibitory activity. However, the obstacle faced was that not all variations of chalcone showed good bacterial inhibitory activity. The trend of increasing or decreasing antibacterial activity due to variations in the location and type of substituent in chalcone is difficult to detect, because comparative data on the inhibitory activity of chalcone are not current or are no longer relevant to current conditions where the test bacteria have mutation as a form of adaptation or resistance to antibiotics. Objective: This research was conducted to provide current data on the antibacterial activity of chalcone against gram-positive and gram-negative bacteria. Methods: Chalcone was synthesized by Claisen-Schmidt condensation and activity test by diffusion method. Results: The yield of chalcone obtained in this study was 96.15%, with the percent purity based on the results of GC-MS was 100%. Inhibitory activity of chalcone on gram-negative bacteria Escherichia coli is in the strong category with an inhibitory value of 81.30% while Acinetobacter is weak with a percentage of 43.0%. In gram-positive bacteria Staphylococcus aureus the inhibitory ability is moderate with a percentage of 64.0%, while in Staphylococcus epidermidis and Bacillus sp the inhibitory activity is weak with a percentage of 35.5% and 43.0%, respectively. Conclusion: Chalcone have strong activity on Gram-negative bacteria and tend to be moderate on Gram-positive bacteria.
In House Training Metodologi Penelitian Pendidikan untuk Meningkatkan Kemampuan Guru Menghasilkan Artikel Ilmiah Ramadani, Shefa Dwijayanti; Christiyani Kusumaningrum, Serafica Btari
Darmabakti : Jurnal Pengabdian dan Pemberdayaan Masyarakat Vol 5 No 01 (2024): Darmabakti : Junal Pengabdian dan Pemberdayaan Masyarakat
Publisher : Lembaga Peneliian dan Pengabdian Masyarakat (LPPM) Universitas Islam Madura (UIM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31102/darmabakti.2024.5.01.39-45

Abstract

Publikasi ilmiah menjadi sangat penting peranannya dalam pengembangan keilmuan maupun pengembangan profesionalisme dan karir guru. Sayangnya, kemampuan guru dalam merumuskan ide penelitian, menentukan desain penelitian, menetapkan dan melakukan pengambilan data, mengembangkan instrumen penelitian, serta melalukan analisis data yang sesuai dengan jenis penelitian menjadi faktor penghambat yang utama untuk menghasilkan karya ilmiah. Pengabdian ini bertujuan untuk meningkatkan pengetahuan metodologi penelitian pendidikan guru di SMAN 1 dan SMAN 2 Grabag, Kabupaten Magelang. Metode pengabdian menggunakan model In House Training yang meliputi 3 fase kegiatan yaitu fase perencanaan, pelaksanaan, dan evaluasi kegiatan. Hasil kegiatan menunjukkan bahwa pemahaman peserta mengenai pentingnya memahami metodologi penelitian untuk menghasilkan karya ilmiah meningkat sebesar 39,79%. Selain itu, terdapat peningkatan sebanyak 43,81% pada aspek pemahaman peserta terhadap ragam metodologi penelitian pendidikan. Dengan demikian, kegiatan pengabdian yang dilakukan mampu memberikan ruang dan kesempatan bagi guru untuk merefresh kembali pengetahuan teoritis dan praktis dalam mengembangkan kemampuannya dalam meneliti.
Booklet development based on identification of medicinal plants in cempaka lake and hill, kebumen regency Darmawan, Ericka; Christiyani Kusumaningrum, Serafica Btari; Yufita, Andira
JPBIO (Jurnal Pendidikan Biologi) Vol 9, No 2 (2024): November 2024
Publisher : STKIP Persada Khatulistiwa Sintang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31932/jpbio.v9i2.3500

Abstract

This research aims to develop information media in the form of a booklet of medicinal plants found in Cempaka Lake and Hill, how to use medicinal plants for traditional medicine, assessing the feasibility of the developed booklet, and the community's response to the developed booklet. The research method used is Exploration and R&D (Research and Development) with the ADDIE development model, which consists of 5 stages: Analysis, Design, Development, Implementation, and Evaluation. Based on the results of exploration by walking along the hiking trail via Purwonegoro Banjarnegara, and the hiking trails via Sempor, and Kebumen, 21 species of medicinal plants were identified which were grouped into 7 classes including Magnoliopsida, Liliopsida, Lycopodiinae, Dycotyledoneae, Angiospermae, Monocotyledonae, and Asteridae. Methods for processing medicinal plants include boiling, pounding, brewing, grating, crushing, and also without processing (used directly). The developed booklet is included in the very valid category with an average percentage of 83.3% on the material aspect validity assessment and 97.72% (very valid) on the media aspect validity assessment. The community's response results showed that the booklet was convenient to use with an average total percentage of 95.93% (very feasible category) used as a source of information for around Cempaka Lake and Hill.
Co-Authors Ericka Darmawan Sepvianti, Wiwit Shefa Dwijayanti Ramadani Yufita, Andira