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All Journal Humantech : Jurnal Ilmiah Multidisiplin Indonesia Innovation in Health for Society
Naripradnya, Putu Saradevi
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Religion Economics, Econometrics & Finance Education Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

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Review: Tablet Effervescent dari Ekstrak Daun Alpukat (Persea americana Mill.) sebagai Peluruh Batu Ginjal pada Tikus Jantan Galur Wistar (Ratus norvegicus) Naripradnya, Putu Saradevi; Eka Indra Setyawan; I Gusti Ngurah Agung Dewantara Putra
Humantech : Jurnal Ilmiah Multidisiplin Indonesia Vol. 2 No. Spesial Issues 3 (2022): Humantech : Jurnal Ilmiah Multidisiplin Indonesia
Publisher : Program Studi Akuntansi IKOPIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/ht.v2iSpesial Issues 3.1507

Abstract

Kidney stones are a health disorder characterized by the appearance of stones in the uropoetic system. Kidney stones can cause infection and cause inflammation so that they can interfere with the smooth flow of urine. If urine flow is obstructed and there is accumulation of urine in the kidneys, it will cause a decrease in the physiological function of the kidneys. The purpose of this review journal is to determine the formulation and evaluation of avocado leaf effervescent tablets (Persea americana Mill.), The method of kidney stone decay test from avocado leaf effervescent tablets (Persea americana Mill.) In test animals, kidney stone decay test results from tablets. avocado leaf effervescent (Persea americana Mill.) in test animals, as well as the most effective dose used in the decay of kidney stones from avocado leaf effervescent tablets (Persea americana Mill.). Avocado leaves can be made as effervescent tablets to shed kidney stones because they dissolve more easily, are absorbed more quickly, and are more stable when compared to liquid preparations. Therefore, avocado leaf extract can be made into effervescent tablets to treat kidney stones.
Application D-Optimal method on the optimization of green tea (Camellia sinensis L.) formulation Andina, Ni Kadek Devi Pradnya; Darmawan, Fiki Dwi; Dewi, Ni Putu Intan Satya; Naripradnya, Putu Saradevi; Wijaya, Hendra; Parta, I Putu Rizki Karisma; Sutri, Wiratama Kadek; Angelina, Ariyanthini Elisabeth; Setyawan, Eka Indra
Innovation in Health for Society Vol 1 No 2 (2021): July - December
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ihs.6331

Abstract

Green tea leaves contain many polyphenols and antioxidants that can reduce cell damage and prevent premature ageing. Green tea extract is made in gel preparation to make it easier to use and increase convenience. HPMC base with propylene glycol additives can increase drug release and penetration into the skin. This study aims to optimize HPMC and propylene glycol levels in green tea extract gel formulations using the D-optimal method and calculate the total release of polyphenols using the Franz diffusion cell method. The extract is produced by infundation. The gel preparation was formulated by varying HPMC and propylene glycol levels in the manufacturing process. Each gel was evaluated for its physical properties, namely viscosity test, pH test, and dispersion test. The physical properties data obtained were then analyzed using Design-Expert software in the mixture design program to get the optimum formula. The optimum procedure brought was HPMC with a concentration of 6% and propylene glycol with a concentration of 17%, resulting in the best correlation between viscosity, dispersion, and pH, with a desirability value of 0.921. In the green tea gel preparation, the resulting concentration was 8.00 GAE/g sample, and the gel content was released at 360 min. was 3.30 GAE/g sample. Keywords: D-Optional mixture design; green tea; HPMC; polyphenols; pharmacy care
Co-Authors Andina, Ni Kadek Devi Pradnya Angelina, Ariyanthini Elisabeth Darmawan, Fiki Dwi Dewi, Ni Putu Intan Satya Eka Indra Setyawan Eka Indra Setyawan Hendra Wijaya I Gusti Ngurah Agung Dewantara Putra Parta, I Putu Rizki Karisma Sutri, Wiratama Kadek