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Characteristics of Patients with Acute Respiratory Infections Using Antibiotics at Hospital X Haryani, Mega; Sormin, Ida Paulina; Liandhajani, Liandhajani
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1527

Infection channel Respiratory acute (ARI) includes a number involving infections various part channel breath, of nose and throat until bronchi and lungs. Use antibiotics often required For treat ARI, though approach prevention like promotion cleanliness hands, management environment, and education society is also very important. Factors like type gender, age, education, occupation, marital status, and smoking status join in role in increase risk affected by ISPA. Study This aim For identify characteristics patients suffering from ARI with various aspect covers type gender, range age, level education, type employment, marital status, and smoking status. Study This use design descriptive observational that utilizes secondary data from notes document medical ARI patients at the center record Hospital. Total samples observed in study This is as many as 110 patients. Analysis show domination patient women (56.3%), which is possible influenced by factors biological, hormonal, and social. Age patients at Hospital X are dominated by groups age 18-30 years (50%), which is likely big influenced by style life and activities population on a range age This. Majority patient in study This own education undergraduate level (33.6%). Patients with work as employee private reached 30%, meanwhile percentage patients who smoke reached 54.5%, which shows significant prevalence in population This. In research This, of the total 110 patients at Hospital X, the majority is Woman. Group age the most is 18-30 years old, which is often active in a way social and productive. By education, in part big patient own background behind education high.

EDUKASI DAGUSIBU (DAPATKAN, GUNAKAN, SIMPAN, BUANG) OBAT DI KALIBARU RW.10, KECAMATAN CILINCING, JAKARTA UTARA Astiani, Rangki; Liandhajani, Liandhajani; Halim, Guntoro; Susilowati, Sri Endah; Hakim, Muhammad Lukman; Firman, Firman; Kristina, Eka
BERDIKARI Vol 7, No 2 (2024): Jurnal Berdikari
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/berdikari.v7i2.7944

Obat berperan penting dalam perawatan kesehatan, namun penggunaannya yang tidak tepat dapat berisiko bagi kesehatan dan lingkungan. Untuk mengatasi masalah ini, program DAGUSIBU (Dapatkan, Gunakan, Simpan, Buang) disosialisasikan untuk meningkatkan pengetahuan masyarakat tentang pengelolaan obat yang benar. Tujuan kegiatan ini adalah memberikan edukasi tentang penggolongan obat, serta cara memperoleh,menggunakan, menyimpan, dan membuang obat dengan benar, guna mengurangi kesalahan penggunaan. Metode pelaksanaan melibatkan penyuluhan dan distribusi brosur pada 10 Agustus 2024 di Kalibaru RW 10, Kecamatan Cilincing, Jakarta Utara. Kegiatan dilakukan dengan presentasi materi menggunakan PowerPoint selama 120 menit, diikuti oleh diskusi interaktif dan sesi tanya jawab. Materi yang disampaikan mencakup pengertian obat, penggolongan obat (obat bebas, obat keras, dll.), serta prosedur yang benar untuk pengelolaan obat. Hasil kegiatan menunjukkan partisipasi aktif dari masyarakat dalam diskusi dan tanya jawab. Pengetahuan peserta meningkat tentang cara mendapatkan obatyang benar, penggunaan yang tepat, penyimpanan yang sesuai, dan pembuangan yang aman. Diskusi interaktif mengungkapkan rasa ingin tahu peserta dan kesadaran akan pentingnya pengelolaan obat yang benar. Kegiatan ini berhasil mencapai tujuannya, meningkatkan pemahaman masyarakat, dan diharapkan dapat membantu mencegah kesalahan penggunaan obat di lingkungan keluarga.

The Effect Of N-Hexane, Ethyl Acetate, And Water Fractions Of Peanut Seeds (Arachis Hypogaea L.) On Antioxidant Activity With The Dpph Method Retno, Kumoro; Liandhajani, Liandhajani; Putra, Andriansyah Mas Jaya
Al Makki Health Informatics Journal Vol. 3 No. 4 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i4.58

Free radicals are one of the causes of various degenerative diseases, for example cardiovascular, high blood pressure, stroke, cirrhosis of the liver, cataracts, diabetes mellitus, and cancer. Antioxidants are compounds that can absorb or neutralize free radicals so that they are able to prevent disease due to damage to body cells, one of the plants that can be used as a natural source of antioxidants is peanut seeds. Peanut seeds contain flavonoid compounds that have the ability to act as antioxidants. The purpose of this study is to determine the presence of antioxidant activity, maximum concentration, EC50(ppm), and differences in antioxidant activity of n-hexane fraction, ethyl acetate fraction, and water fraction in peanut seeds in vitro. The method used in peanut seed extraction is remaceration with 96% ethanol solvent for 3 days. This study used solvents of n-hexane fraction, ethyl acetate fraction, and water fraction. Fractionation process for separation of compounds. The results of each fraction were tested by phytochemical screening and tested by thin layer chromatography (KLT). Quantitative analysis of antioxidants using the DPPH method at a maximum wavelength of 517.5 nm. The results of the study showed that the average yield from the extract was 24.15%. The n-hexane fraction, ethyl acetate fraction, and water fraction of peanut seed extract were 20.33%, 25.61%, 33.28%, respectively. The results of phytochemical screening obtained the results that were positive for flavonoids containing antioxidants in vitro. An average of EC50(ppm) was obtained in the standard quercetin, n-hexane fraction, ethyl acetate fraction, water fraction of 12.02 ppm; 10.62 ppm; 12.25 ppm; 11.75 ppm. The results of the statistical test according to ANAVA I showed that the significance was more than 0.05 which was 0.105 so that it can be concluded that the difference was not significant between the concentration groups of n-hexane, ethyl acetate, and water fractions of peanut seed extract in invitro antioxidant activity.

The Effect Of N-Hexane, Ethyl Acetate, And Water Fractions Of Peanut Seeds (Arachis Hypogaea L.) On Antioxidant Activity With The Dpph Method Retno, Kumoro; Liandhajani, Liandhajani; Putra, Andriansyah Mas Jaya
Al Makki Health Informatics Journal Vol. 3 No. 4 (2025): Al Makki Health Informatics Journal
Publisher : Al Makki Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57185/hij.v3i4.58

Free radicals are one of the causes of various degenerative diseases, for example cardiovascular, high blood pressure, stroke, cirrhosis of the liver, cataracts, diabetes mellitus, and cancer. Antioxidants are compounds that can absorb or neutralize free radicals so that they are able to prevent disease due to damage to body cells, one of the plants that can be used as a natural source of antioxidants is peanut seeds. Peanut seeds contain flavonoid compounds that have the ability to act as antioxidants. The purpose of this study is to determine the presence of antioxidant activity, maximum concentration, EC50(ppm), and differences in antioxidant activity of n-hexane fraction, ethyl acetate fraction, and water fraction in peanut seeds in vitro. The method used in peanut seed extraction is remaceration with 96% ethanol solvent for 3 days. This study used solvents of n-hexane fraction, ethyl acetate fraction, and water fraction. Fractionation process for separation of compounds. The results of each fraction were tested by phytochemical screening and tested by thin layer chromatography (KLT). Quantitative analysis of antioxidants using the DPPH method at a maximum wavelength of 517.5 nm. The results of the study showed that the average yield from the extract was 24.15%. The n-hexane fraction, ethyl acetate fraction, and water fraction of peanut seed extract were 20.33%, 25.61%, 33.28%, respectively. The results of phytochemical screening obtained the results that were positive for flavonoids containing antioxidants in vitro. An average of EC50(ppm) was obtained in the standard quercetin, n-hexane fraction, ethyl acetate fraction, water fraction of 12.02 ppm; 10.62 ppm; 12.25 ppm; 11.75 ppm. The results of the statistical test according to ANAVA I showed that the significance was more than 0.05 which was 0.105 so that it can be concluded that the difference was not significant between the concentration groups of n-hexane, ethyl acetate, and water fractions of peanut seed extract in invitro antioxidant activity.

Cost Effectiveness Analysis Therapeutic Outcome Antihipertensi Kombinasi A ( Valsartan, Amlodipin, Furosemid) Dan Kombinasi B (Valsartan, Hidroklortiazid, Amlodipin) Pasien Rawat Jalan Di Rumah Sakit Umum Pendidikan Jakarta Malasari, Wahyuni; Sormin, Ida Paulina; Liandhajani, Liandhajani; Lukas, Stefanus
Jurnal Ners Vol. 10 No. 2 (2026)
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jn.v10i2.55970

Hipertensi merupakan penyakit tidak menular yang memerlukan terapi jangka panjang, sehingga biaya pengobatan menjadi faktor krusial dalam keberhasilan terapi. Pemilihan kombinasi antihipertensi yang efektif secara klinis dan efisien secara ekonomi sangat penting untuk mengoptimalkan manajemen pasien. Penelitian ini bertujuan untuk menganalisis efektivitas biaya antara dua terapi, yaitu Kombinasi A (Valsartan, Amlodipin, Furosemid) dan Kombinasi B (Valsartan, Hidroklortiazid, Amlodipin) pada pasien rawat jalan di Rumah Sakit Umum Pendidikan Jakarta periode Januari-Juni 2025. Penelitian ini menggunakan desain studi potong lintang (Cross-Sectional) dengan pengambilan data secara retrospektif dari rekam medis. Sampel penelitian berjumlah 216 pasien yang dibagi rata menjadi 108 pasien per kelompok. Efektivitas terapi diukur berdasarkan persentase ketercapaian target tekanan darah terkontrol (MAP). Analisis ekonomi dihitung berdasarkan biaya medis langsung yang meliputi biaya obat, jasa dokter, dan pemeriksaan laboratorium menggunakan parameter Average Cost-Effectiveness Ratio (ACER) dan Incremental Cost-Effectiveness Ratio (ICER). Hasil penelitian menunjukkan mayoritas pasien adalah perempuan (51,4%) dengan kelompok usia terbanyak 50-59 tahun (32,4%). Kombinasi A memiliki efektivitas klinis lebih tinggi (93,5%) dibandingkan Kombinasi B (72,2%). Total biaya medis langsung Kombinasi A (Rp392.326.893) lebih rendah daripada Kombinasi B (Rp452.799.996). Nilai ACER Kombinasi A adalah Rp4.038.777/MAP, lebih rendah dari Kombinasi B (Rp4.498.311/MAP). Perhitungan ICER menghasilkan nilai negatif (-2.839.112) yang menunjukkan posisi dominan Kombinasi A. Kesimpulannya, terapi Kombinasi A lebih efektif secara klinis dan biaya dibandingkan Kombinasi

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